Search Results - "Smith, Hannah L."
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Sensitization of silicon by singlet exciton fission in tetracene
Published in Nature (London) (01-07-2019)“…Silicon dominates contemporary solar cell technologies 1 . But when absorbing photons, silicon (like other semiconductors) wastes energy in excess of its…”
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IL-6 secretion in osteoarthritis patients is mediated by chondrocyte-synovial fibroblast cross-talk and is enhanced by obesity
Published in Scientific reports (14-06-2017)“…Increasing evidence suggests that inflammation plays a central role in driving joint pathology in certain patients with osteoarthritis (OA). Since many…”
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3
A myelin-related transcriptomic profile is shared by Pitt–Hopkins syndrome models and human autism spectrum disorder
Published in Nature neuroscience (01-03-2020)“…Autism spectrum disorder (ASD) is genetically heterogeneous with convergent symptomatology, suggesting common dysregulated pathways. In this study, we analyzed…”
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Tri-Lineage Differentiation Potential of Osteosarcoma Cell Lines and Human Bone Marrow Stromal Cells from Different Anatomical Locations
Published in International journal of molecular sciences (01-02-2023)“…The bone cancer osteosarcoma, found mainly in adolescents, routinely forms around the growth plate/metaphysis of long bones. Bone marrow composition changes…”
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Controlled n‐Doping of Naphthalene‐Diimide‐Based 2D Polymers
Published in Advanced materials (Weinheim) (01-06-2022)“…2D polymers (2DPs) are promising as structurally well‐defined, permanently porous, organic semiconductors. However, 2DPs are nearly always isolated as closed…”
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6
Solution-Processed Organic and Halide Perovskite Transistors on Hydrophobic Surfaces
Published in ACS applied materials & interfaces (31-05-2017)“…Solution-processable electronic devices are highly desirable due to their low cost and compatibility with flexible substrates. However, they are often…”
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The Role of Pre-Clinical 3-Dimensional Models of Osteosarcoma
Published in International journal of molecular sciences (31-07-2020)“…Treatment for osteosarcoma (OS) has been largely unchanged for several decades, with typical therapies being a mixture of chemotherapy and surgery. Although…”
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Interaction of Axonal Chondrolectin with Collagen XIXa1 Is Necessary for Precise Neuromuscular Junction Formation
Published in Cell reports (Cambridge) (29-10-2019)“…Chondrolectin (Chodl) is needed for motor axon extension in zebrafish and is dysregulated in mouse models of spinal muscular atrophy (SMA). However, the…”
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Elevated Salt or Angiotensin II Levels Induce CD38+ Innate Immune Cells in the Presence of Granulocyte-Macrophage Colony Stimulating Factor
Published in Cells (Basel, Switzerland) (01-08-2024)“…Hypertension (HTN) impacts almost half of adults, predisposing them to cardiovascular disease and renal damage. Salt-sensitive HTN (SSHTN) and angiotensin II…”
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Interaction of Axonal Chondrolectin with Collagen XIXa1 Is Necessary for Precise Neuromuscular Junction Formation
Published in Cell reports (Cambridge) (25-08-2020)Get full text
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Implementing Standardized Patient Caregivers to Practice Difficult Conversations in a Pediatric Dentistry Course
Published in MedEdPORTAL (2022)“…Standardized patient (SP) methodology has been used in health professional education to help students develop communication, deeper diagnostic reasoning, and…”
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Domain binding and isotype dictate the activity of anti-human OX40 antibodies
Published in Journal for immunotherapy of cancer (01-12-2020)“…BackgroundPrevious data suggests that anti-OX40 mAb can elicit anti-tumor effects in mice through deletion of Tregs. However, OX40 also has powerful…”
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ATR, CHK1 and WEE1 inhibitors cause homologous recombination repair deficiency to induce synthetic lethality with PARP inhibitors
Published in British journal of cancer (21-09-2024)“…Purpose PARP inhibitors (PARPi) are effective in homologous recombination repair (HRR) defective (HRD) cancers. To (re)sensitise HRR proficient (HRP) tumours…”
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14
Ultrasound biomicroscopy in dogs suggests postoperative ocular hypertension may be associated with ciliary cleft changes related to cataract surgery
Published in Journal of the American Veterinary Medical Association (19-09-2024)“…To determine whether novel pre- and postsurgical ultrasound biomicroscopy (UBM) measurements of the canine ciliary cleft (CC) are associated with postoperative…”
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Treatment of equine keratomycosis, part 1: selection of appropriate therapy based on clinical presentation and diagnostic testing improves clinical outcomes
Published in Journal of the American Veterinary Medical Association (23-10-2024)“…To determine clinical outcome, treatment costs, and hospitalization duration in horses treated for keratomycosis and identify ophthalmic examination and…”
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Use of integrated metabolomics, transcriptomics, and signal protein profile to characterize the effector function and associated metabotype of polarized macrophage phenotypes
Published in Journal of leukocyte biology (01-03-2022)“…MΦs display remarkable plasticity and the ability to activate diverse responses to a host of intracellular and external stimuli. Despite extensive…”
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Clinical Characteristics and Care Trajectories of Transgender and Gender Diverse Patients With Cancer Seen in a Pediatric Gender Clinic
Published in Psycho-oncology (Chichester, England) (01-11-2024)“…ABSTRACT Background There is very little information on the experiences of transgender and gender diverse (TGD) youth with cancer. Aims To examine clinical…”
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Exploring the Synergy between PARP and CHK1 Inhibition in Matched BRCA2 Mutant and Corrected Cells
Published in Cancers (04-04-2020)“…PARP inhibition results in the accumulation of DNA SSBs, causing replication stress (RS) and lesions that can only be resolved by homologous recombination…”
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n‐Doping of a Low‐Electron‐Affinity Polymer Used as an Electron‐Transport Layer in Organic Light‐Emitting Diodes
Published in Advanced functional materials (01-04-2020)“…n‐Doping electron‐transport layers (ETLs) increases their conductivity and improves electron injection into organic light‐emitting diodes (OLEDs). Because of…”
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Update on Immune Mechanisms in Hypertension
Published in American journal of hypertension (03-10-2022)“…Abstract The contribution of immune cells in the initiation and maintenance of hypertension is undeniable. Several studies have established the association…”
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