Search Results - "Smith, Hannah J"
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Neuronal mTORC1 inhibition promotes longevity without suppressing anabolic growth and reproduction in C. elegans
Published in PLoS genetics (18-09-2023)“…mTORC1 (mechanistic target of rapamycin complex 1) is a metabolic sensor that promotes growth when nutrients are abundant. Ubiquitous inhibition of mTORC1…”
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Improving trainee engagement in science: Lessons from a virtual seminar series
Published in Translational medicine of aging (2020)“…To be a successful researcher, you are expected to have important skills beyond the bench such as being able to ask questions, talk about science with your…”
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Causal roles of mitochondrial dynamics in longevity and healthy aging
Published in EMBO reports (05-12-2019)“…Mitochondria are organized in the cell in the form of a dynamic, interconnected network. Mitochondrial dynamics, regulated by mitochondrial fission, fusion,…”
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Metabolic Communication and Healthy Aging: Where Should We Focus Our Energy?
Published in Developmental cell (20-07-2020)“…Aging is associated with a loss of metabolic homeostasis and plasticity, which is causally linked to multiple age-onset pathologies. The majority of the…”
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Parents’ sensemaking processes in the identification of developmental delays and engagement with early intervention services
Published in Social science & medicine (1982) (01-06-2020)“…•Heuristic processes influenced the Common Sense Model when identifying a delay.•Self-efficacy may facilitate transitions between stimuli and…”
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Ozone Responsive Gene Expression as a Model for Describing Repeat Exposure Response Trajectories and Interindividual Toxicodynamic Variability In Vitro
Published in Toxicological sciences (28-12-2021)“…Abstract Inhaled chemical/material exposures are a ubiquitous part of daily life around the world. There is a need to evaluate potential adverse effects of…”
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Automated Torso Contour Extraction from Clinical Cardiac MR Slices for 3D Torso Reconstruction
Published in 2022 44th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC) (01-07-2022)“…Whilst the electrocardiogram (ECG) is an essential tool for diagnosing cardiac electrical abnormalities, its characteristics are dependent on anatomical…”
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Conference Proceeding Journal Article -
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Unravelling the Mechanistic Links between Pro-Arrhythmia and Mechanical Function
Published in 2020 Computing in Cardiology (13-09-2020)“…Sudden cardiac death (SCD) from ventricular arrhythmias is a leading cause of mortality. Accurate arrhythmic risk stratification is vital for preventative…”
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Conference Proceeding -
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Metabolic Communication and Healthy Aging: Where Do We Focus Our Energy?
Published in Developmental cell (02-07-2020)“…Aging is associated with a loss of metabolic homeostasis and plasticity, which is causally linked to multiple age-onset pathologies. The majority of the…”
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Anatomical basis of human sex differences in ECG identified by automated torso-cardiac three-dimensional reconstruction
Published 21-12-2023“…Background and Aims: The electrocardiogram (ECG) is routinely used for diagnosis and risk stratification following myocardial infarction (MI), though its…”
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