Search Results - "Smith, David"
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Understanding vaccine hesitancy around vaccines and vaccination from a global perspective: A systematic review of published literature, 2007–2012
Published in Vaccine (17-04-2014)“…Highlights • Vaccine hesitancy is a complex issue driven by a variety of context-specific factors. • Most studies were conducted in Europe and the Americas,…”
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Working from home in the time of COVID-19: how to best preserve occupational health?
Published in Occupational and environmental medicine (London, England) (01-07-2020)Get full text
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A Practical Review of Proteasome Pharmacology
Published in Pharmacological reviews (01-04-2019)“…The ubiquitin proteasome system (UPS) degrades individual proteins in a highly regulated fashion and is responsible for the degradation of misfolded, damaged,…”
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Homocysteine, B Vitamins, and Cognitive Impairment
Published in Annual review of nutrition (17-07-2016)“…Moderately elevated plasma total homocysteine (tHcy) is a strong modifiable risk factor for vascular dementia and Alzheimer's disease. Prospectively, elevated…”
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A full-parameter unidirectional metamaterial cloak for microwaves
Published in Nature materials (01-01-2013)“…Metamaterials offer a unique potential to guide the propagation of light. However, existing designs of devices such as invisibility cloaks require a…”
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Analysis of the structural diversity, substitution patterns, and frequency of nitrogen heterocycles among U.S. FDA approved pharmaceuticals
Published in Journal of medicinal chemistry (26-12-2014)“…Nitrogen heterocycles are among the most significant structural components of pharmaceuticals. Analysis of our database of U.S. FDA approved drugs reveals that…”
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Coral bleaching patterns are the outcome of complex biological and environmental networking
Published in Global change biology (01-01-2020)“…Continued declines in coral reef health over the past three decades have been punctuated by severe mass coral bleaching‐induced mortality events that have…”
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Extreme nanophotonics from ultrathin metallic gaps
Published in Nature materials (01-07-2019)“…Ultrathin dielectric gaps between metals can trap plasmonic optical modes with surprisingly low loss and with volumes below 1 nm 3 . We review the origin and…”
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Espressogate
Published in EMBO reports (10-10-2024)“…A food services scandal as a sign of bigger problems that haunt universities…”
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Dynamically reconfigurable holographic metasurface aperture for a Mills-Cross monochromatic microwave camera
Published in Optics express (05-03-2018)“…We present a reconfigurable, dynamic beam steering holographic metasurface aperture to synthesize a microwave camera at K-band frequencies. The aperture…”
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Your “out of the office” email is not fooling me
Published in EMBO reports (12-06-2024)“…Don’t fool yourself to think that you are safe from emails just because you enabled the “Out of office” function. It is not an ‘Off’ button that grants you…”
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Extreme-angle broadband metamaterial lens
Published in Nature materials (01-02-2010)“…For centuries, the conventional approach to lens design has been to grind the surfaces of a uniform material in such a manner as to sculpt the paths that rays…”
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Redefining meaning and success in science, research and teaching
Published in EMBO reports (14-05-2024)“…The mid-life crisis to find meaning in life affects even academics. At the end of the day, however you redefine your goals in life, it is interactions with…”
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Finding value and beauty in obsolete scientific equipment
Published in EMBO reports (12-03-2024)“…Most scientific equipment gets heedlessly thrown away when it’s no longer of use. But these often beautiful and well-crafted tools deserve a better fate, if…”
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Small-molecule SMAC mimetics as new cancer therapeutics
Published in Pharmacology & therapeutics (Oxford) (01-10-2014)“…Apoptosis is a tightly regulated cellular process and faulty regulation of apoptosis is a hallmark of human cancers. Targeting key apoptosis regulators with…”
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A common mechanism of proteasome impairment by neurodegenerative disease-associated oligomers
Published in Nature communications (15-03-2018)“…Protein accumulation and aggregation with a concomitant loss of proteostasis often contribute to neurodegenerative diseases, and the ubiquitin–proteasome…”
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Clinical and analytical validation of FoundationOne®CDx, a comprehensive genomic profiling assay for solid tumors
Published in PloS one (01-01-2022)“…FoundationOne®CDx (F1CDx) is a United States (US) Food and Drug Administration (FDA)-approved companion diagnostic test to identify patients who may benefit…”
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Measuring vaccine confidence: analysis of data obtained by a media surveillance system used to analyse public concerns about vaccines
Published in The Lancet infectious diseases (01-07-2013)“…Summary Background The intensity, spread, and effects of public opinion about vaccines are growing as new modes of communication speed up information sharing,…”
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Things I wish I had done as a graduate student
Published in EMBO reports (06-12-2023)“…Making the most of opportunities available during graduate school can pay dividends later on…”
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Disturbance Observer Design for Nonlinear Systems Represented by Input-Output Models
Published in IEEE transactions on industrial electronics (1982) (01-02-2020)“…A new approach to the design of nonlinear disturbance observers (DOBs) for a class of nonlinear systems described by input-output differential equations is…”
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