Search Results - "Smith, C A"

Large scale variation in the rate of germ-line de novo mutation, base composition, divergence and diversity in humans by Smith, Thomas C A, Arndt, Peter F, Eyre-Walker, Adam

“…It has long been suspected that the rate of mutation varies across the human genome at a large scale based on the divergence between humans and other species…”
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"Exercise as medicine" in chronic kidney disease by Wilkinson, T. J., Shur, N. F., Smith, A. C.

“…Exercise and physical activity are increasingly becoming key tools in the treatment and prevention of several medical conditions including arthritis and…”
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The Nucleus Accumbens: Mechanisms of Addiction across Drug Classes Reflect the Importance of Glutamate Homeostasis by Scofield, M D, Heinsbroek, J A, Gipson, C D, Kupchik, Y M, Spencer, S, Smith, A C W, Roberts-Wolfe, D, Kalivas, P W

“…The nucleus accumbens is a major input structure of the basal ganglia and integrates information from cortical and limbic structures to mediate goal-directed…”
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Supply Induced Interharmonic Effects in Wound Rotor and Doubly-Fed Induction Generators by Djurovic, S., Vilchis-Rodriguez, D. S., Smith, A. C.

“…This paper investigates the spectral effects that stator supply harmonics can induce in wound rotor and doubly-fed induction generators. The purpose of this…”
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The presence or absence of midsagittal tissue bridges and walking: a retrospective cohort study in spinal cord injury by Thornton, W. A., Marzloff, G., Ryder, S., Best, A., Rasheed, K., Coons, D., Smith, A. C.

“…Study design Cohort study. Retrospective analysis of T2-weighted magnetic resonance images (MRIs) and clinical documentation. Objectives To evaluate the…”
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Detection of Hostile Intent by Spatial Movements by Patton, Colleen E., Wickens, Christopher D., Smith, C. A. P., Clegg, Benjamin A.

“…Objective The ability of people to infer intentions from movement of other vessels was investigated. Across three levels of variability in movements in the…”
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Rendezvous Under Temporal Uncertainty by Patton, Colleen E., Wickens, Christopher D., Noble, Kayla M., Clegg, Benjamin A., Smith, C. A. P.

“…Objective Three experiments sought to understand performance limitations in controlling a ship attempting to meet another moving ship that approached from…”
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New evidence from exceptionally “well-preserved” specimens sheds light on the structure of the ammonite brachial crown by Smith, C. P. A., Landman, N. H., Bardin, J., Kruta, I.

“…Ammonite soft body remains are rarely preserved. One of the biggest enigmas is the morphology of the ammonite brachial crown that has, up till now, never been…”
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Investigation of the safety and feasibility of AAV1/SERCA2a gene transfer in patients with chronic heart failure supported with a left ventricular assist device – the SERCA-LVAD TRIAL by Lyon, A. R., Babalis, D., Morley-Smith, A. C., Hedger, M., Suarez Barrientos, A., Foldes, G., Couch, L. S., Chowdhury, R. A., Tzortzis, K. N., Peters, N. S., Rog-Zielinska, E. A., Yang, H-Y, Welch, S., Bowles, C. T., Rahman Haley, S., Bell, A. R., Rice, A., Sasikaran, T., Johnson, N. A., Falaschetti, E., Parameshwar, J., Lewis, C., Tsui, S., Simon, A., Pepper, J., Rudy, J. J., Zsebo, K. M., Macleod, K. T., Terracciano, C. M., Hajjar, R. J., Banner, N., Harding, S. E.

“…The SERCA-LVAD trial was a phase 2a trial assessing the safety and feasibility of delivering an adeno-associated vector 1 carrying the cardiac isoform of the…”
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Acute postnatal exposure to di(2-ethylhexyl) phthalate adversely impacts hippocampal development in the male rat by Smith, C.A, MacDonald, A, Holahan, M.R

“…Abstract The distribution of CA3 hippocampal axonal terminal fields undergo a period of widespread connectivity-based changes in the early postnatal stages of…”
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Symptom-burden in people living with frailty and chronic kidney disease by Nixon, A C, Wilkinson, T J, Young, H M L, Taal, M W, Pendleton, N, Mitra, S, Brady, M E, Dhaygude, A P, Smith, A C

“…Frailty is independently associated with worse health-related quality of life (HRQOL) in chronic kidney disease (CKD). However, the relationship between…”
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Programming of adiposity in childhood and adolescence: associations with birth weight and cord blood adipokines by Simpson, Joy, Smith, Andrew DAC, Fraser, Abigail, Sattar, Naveed, Lindsay, Robert S, Ring, Susan M, Tilling, Kate, Davey Smith, George, Lawlor, Debbie A, Nelson, Scott M

“…Context:Exposure to maternal adiposity during pregnancy is associated with higher offspring birthweight and greater adiposity through childhood and adult life…”
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Effect of Visualization Training on Uncertain Spatial Trajectory Predictions by Pugh, Ashley J., Wickens, Christopher D., Herdener, Nathan, Clegg, Benjamin A., Smith, C. A. P.

“…Objective: The goal of this study was to explore the ways in which visualizations influence the prediction of uncertain spatial trajectories (e.g., the unknown…”
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Disproportional effects of Igf2 knockout on placental morphology and diffusional exchange characteristics in the mouse by Coan, P. M., Fowden, A. L., Constancia, M., Ferguson‐Smith, A. C., Burton, G. J., Sibley, C. P.

“…Both complete knockout of the Igf2 gene ( Igf2 null +/− ) and knockout of its placental specific transcript alone ( Igf2 P0 +/− ) lead to fetal growth…”
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Detection of Fruit and the Selection of Primate Visual Pigments for Color Vision by Osorio, D., Smith, A. C., Vorobyev, M., Buchanan‐Smith, H. M.

“…Primates have X chromosome genes for cone photopigments with sensitivity maxima from 535 to 562 nm. Old World monkeys and apes (catarrhines) and the New World…”
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Overconfidence in Projecting Uncertain Spatial Trajectories by Herdener, Nathan, Wickens, Christopher D., Clegg, Benjamin A., Smith, C. A. P.

“…Objective The aim of this study was to understand factors that influence the prediction of uncertain spatial trajectories (e.g., the future path of a hurricane…”
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The SFRP family of WNT inhibitors function as novel tumor suppressor genes epigenetically silenced in medulloblastoma by Kongkham, P N, Northcott, P A, Croul, S E, Smith, C A, Taylor, M D, Rutka, J T

“…Medulloblastoma (MB) is the most common malignant pediatric brain tumor. Dysregulation of WNT signaling occurs in up to 20% of cases. Using a genome-wide…”
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Self-reported Dysphagia and Pharyngeal Volume Following Whiplash Injury by Stone, D., Ward, E. C., Bogaardt, H., Heard, R., Martin-Harris, B., Smith, A. C., Elliott, J. M.

“…Difficulty swallowing has been reported following whiplash injury; however, the reasons remain poorly understood. A possible factor may be the observed changes…”
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Response time and sensitivity of the ventilatory response to CO2 in unanesthetized intact dogs: central vs. peripheral chemoreceptors by Smith, C. A, Rodman, J. R, Chenuel, B. J. A, Henderson, K. S, Dempsey, J. A

“…John Rankin Laboratory of Pulmonary Medicine, Department of Population Health Sciences, School of Medicine, University of Wisconsin, Madison, Wisconsin…”
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How history trails and set size influence detection of hostile intentions by Patton, Colleen E., Wickens, Christopher D., Clegg, Benjamin A., Noble, Kayla M., Smith, C. A. P.

“…Previous research suggests people struggle to detect a series of movements that might imply hostile intentions of a vessel, yet this ability is crucial in many…”
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