Search Results - "Smith, Byron"

Changes in the gut microbiome and fermentation products concurrent with enhanced longevity in acarbose-treated mice by Smith, Byron J, Miller, Richard A, Ericsson, Aaron C, Harrison, David C, Strong, Randy, Schmidt, Thomas M

“…Treatment with the α-glucosidase inhibitor acarbose increases median lifespan by approximately 20% in male mice and 5% in females. This longevity extension…”
Get full text

rrnDB: improved tools for interpreting rRNA gene abundance in bacteria and archaea and a new foundation for future development by Stoddard, Steven F, Smith, Byron J, Hein, Robert, Roller, Benjamin R K, Schmidt, Thomas M

“…Microbiologists utilize ribosomal RNA genes as molecular markers of taxonomy in surveys of microbial communities. rRNA genes are often co-located as part of an…”
Get full text

Deep Learning-Based Histopathologic Assessment of Kidney Tissue by Hermsen, Meyke, de Bel, Thomas, den Boer, Marjolijn, Steenbergen, Eric J, Kers, Jesper, Florquin, Sandrine, Roelofs, Joris J T H, Stegall, Mark D, Alexander, Mariam P, Smith, Byron H, Smeets, Bart, Hilbrands, Luuk B, van der Laak, Jeroen A W M

“…The development of deep neural networks is facilitating more advanced digital analysis of histopathologic images. We trained a convolutional neural network for…”
Get full text

Muribaculaceae Genomes Assembled from Metagenomes Suggest Genetic Drivers of Differential Response to Acarbose Treatment in Mice by Smith, Byron J, Miller, Richard A, Schmidt, Thomas M

“…The drug acarbose is used to treat diabetes and, by inhibiting α-amylase in the small intestine, increases the amount of starch entering the lower digestive…”
Get full text

The limitation of using procurement biopsy findings in the assessment of deceased donor kidney quality and outcomes by Budhiraja, Pooja, Heilman, Raymond, Smith, Byron H., Kaplan, Bruce

Get full text

Long-term outcomes of eculizumab-treated positive crossmatch recipients: Allograft survival, histologic findings, and natural history of the donor-specific antibodies by Schinstock, Carrie A., Bentall, Andrew J., Smith, Byron H., Cornell, Lynn D., Everly, Matthew, Gandhi, Manish J., Stegall, Mark D.

“…We aimed to determine the long-term outcomes of eculizumab-treated, positive crossmatch (+XM) kidney transplant recipients compared with +XM and age-matched…”
Get full text

Long-Term Outcomes of Induction Immunosuppression for Kidney Transplant Recipients With HIV Who Have Average Immunologic Risk: An Inverse Probability Treatment Weighting Analysis by El Rifai, Rasha, Bhunia, Kaushik, Fontana, Lauren, Swanson, Kurtis J., Jackson, Scott, Smith, Byron H., Riad, Samy M.

“…We analyzed the Scientific Registry of Transplant Recipients (2004-2022) for primary kidney recipients with HIV who had average immunologic risk and were…”
Get full text

Effects of Social Determinants of Health Care on Pediatric Thyroid Cancer Outcomes in the United States by Gruszczynski, Nelson R., Low, Christopher M., Choby, Garret, Meister, Kara D., Smith, Byron H., Balakrishnan, Karthik

“…Objective To identify social determinants of health care that are associated with poorer pediatric well-differentiated thyroid cancer (WDTC) outcomes and…”
Get full text

Race-free estimated glomerular filtration rate equation in kidney transplant recipients: development and validation study by Raynaud, Marc, Al-Awadhi, Solaf, Juric, Ivana, Divard, Gillian, Lombardi, Yannis, Basic-Jukic, Nikolina, Aubert, Olivier, Dubourg, Laurence, Masson, Ingrid, Mariat, Christophe, Prié, Dominique, Pernin, Vincent, Le Quintrec, Moglie, Larson, Timothy S, Stegall, Mark D, Bikbov, Boris, Ruggenenti, Piero, Mesnard, Laurent, Ibrahim, Hassan N, Nielsen, Marie Bodilsen, Matas, Arthur J, Nankivell, Brian J, Benjamens, Stan, Pol, Robert A, Bakker, Stephan J L, Jouven, Xavier, Legendre, Christophe, Kamar, Nassim, Smith, Byron H, Wadei, Hani M, Durrbach, Antoine, Vincenti, Flavio, Remuzzi, Giuseppe, Lefaucheur, Carmen, Bentall, Andrew J, Loupy, Alexandre

“…To compare the performance of a newly developed race-free kidney recipient specific glomerular filtration rate (GFR) equation with the three current main…”
Get more information

Changes in Glomerular Volume, Sclerosis, and Ischemia at 5 Years after Kidney Transplantation: Incidence and Correlation with Late Graft Failure by Denic, Aleksandar, Bogojevic, Marija, Subramani, Rashmi, Park, Walter D, Smith, Byron H, Alexander, Mariam P, Grande, Joseph P, Kukla, Aleksandra, Schinstock, Carrie A, Bentall, Andrew J, Rule, Andrew D, Stegall, Mark D

“…Glomerular volume, ischemic glomeruli, and global glomerulosclerosis are not consistently assessed on kidney transplant biopsies. The authors evaluated…”
Get full text

Strain-resolved analysis in a randomized trial of antibiotic pretreatment and maintenance dose delivery mode with fecal microbiota transplant for ulcerative colitis by Smith, Byron J., Piceno, Yvette, Zydek, Martin, Zhang, Bing, Syriani, Lara Aboud, Terdiman, Jonathan P., Kassam, Zain, Ma, Averil, Lynch, Susan V., Pollard, Katherine S., El-Nachef, Najwa

“…Fecal microbiota transplant is a promising therapy for ulcerative colitis. Parameters maximizing effectiveness and tolerability are not yet clear, and it is…”
Get full text

Competing Risk Analysis in Renal Allograft Survival: A New Perspective to an Old Problem by El Ters, Mireille, Smith, Byron H., Cosio, Fernando G., Kremers, Walter K.

“…BACKGROUND:Graft survival after kidney transplant (KTX) is often estimated by the Kaplan-Meier (KM) method censoring for competing endpoints, primarily death…”
Get full text

Long-term Outcomes Following Kidney Transplantation From Donors With Acute Kidney Injury by Heilman, Raymond L, Smith, Maxwell L, Smith, Byron H, Kumar, Anjushree, Srinivasan, Ananth, Huskey, Janna L, Khamash, Hasan A, Jadlowiec, Caroline C, Mathur, Amit K, Moss, Adyr A, Reddy, Kunam S

“…BACKGROUND.Kidneys from deceased donors with acute kidney injury (AKI) are more likely to be discarded because of concerns for poor outcomes after…”
Get full text

Managing highly sensitized renal transplant candidates in the era of kidney paired donation and the new kidney allocation system: Is there still a role for desensitization? by Schinstock, Carrie A., Smith, Byron H., Montgomery, Robert A., Jordan, Stanley C., Bentall, Andrew J., Mai, Martin, Khamash, Hasan A., Stegall, Mark D.

“…Kidney paired donation (KPD) and the new kidney allocation system (KAS) in the United States have led to improved transplantation rates for highly sensitized…”
Get full text

1497-P: Comprehensive Metabolic Assessment Reveals Excellent and Stable Glucose Control during First Year after Pancreas Transplantation by JEET KAUR, RAVINDER, RAZA RIZVI, SHAFAQ, REID, COREY, SMITH, BYRON H., KUKLA, ALEKSANDRA, STEGALL, MARK D., KUDVA, YOGISH C.

“…Introduction: Limited data are available regarding comprehensive metabolic evaluation after Pancreas transplantation (PT) for T1DM. Methods: We prospectively…”
Get full text

32 Doses of Bortezomib for Desensitization Is Not Well Tolerated and Is Associated With Only Modest Reductions in Anti-HLA Antibody by Moreno Gonzales, Manuel A, Gandhi, Manish J, Schinstock, Carrie A, Moore, Natalie A, Smith, Byron H, Braaten, Nong Y, Stegall, Mark D

“…BACKGROUNDWe previously showed that bortezomib (BTZ) partially depletes plasma cells, yet has limited efficacy for desensitization in kidney transplant…”
Get full text

Convolutional Neural Networks for the Evaluation of Chronic and Inflammatory Lesions in Kidney Transplant Biopsies by Hermsen, Meyke, Ciompi, Francesco, Adefidipe, Adeyemi, Denic, Aleksandar, Dendooven, Amélie, Smith, Byron H., van Midden, Dominique, Bräsen, Jan Hinrich, Kers, Jesper, Stegall, Mark D., Bándi, Péter, Nguyen, Tri, Swiderska-Chadaj, Zaneta, Smeets, Bart, Hilbrands, Luuk B., van der Laak, Jeroen A.W.M.

“…In kidney transplant biopsies, both inflammation and chronic changes are important features that predict long-term graft survival. Quantitative scoring of…”
Get full text

Transplantation Within 6 Months of Registration does not Enhance Survival for Patients with Perihilar Cholangiocarcinoma by Nasser-Ghodsi, Navine, Eaton, John E, Smith, Byron H, Venkatesh, Sudhakar K, Heimbach, Julie K, Taner, Timucin, Welle, Christopher L, Ilyas, Sumera I, Gores, Gregory J, Rosen, Charles B

“…Determine if timing of transplantation affects patient mortality. Neoadjuvant therapy and liver transplantation has emerged as an excellent treatment option…”
Get full text

Sustained mucosal colonization and fecal metabolic dysfunction by Bacteroides associates with fecal microbial transplant failure in ulcerative colitis patients by Zhang, Bing, Magnaye, Kevin M., Stryker, Emily, Moltzau-Anderson, Jacqueline, Porsche, Cara E., Hertz, Sandra, McCauley, Kathryn E., Smith, Byron J., Zydek, Martin, Pollard, Katherine S., Ma, Averil, El-Nachef, Najwa, Lynch, Susan V.

“…Fecal microbial transplantation (FMT) offers promise for treating ulcerative colitis (UC), though the mechanisms underlying treatment failure are unknown. This…”
Get full text

Risk factors and prophylaxis for nocardiosis in solid organ transplant recipients: A nested case-control study by Yetmar, Zachary A, Chesdachai, Supavit, Duffy, Dustin, Smith, Byron H, Challener, Douglas W, Seville, Maria Teresa, Bosch, Wendelyn, Beam, Elena

“…Nocardia is an opportunistic pathogen that primarily affects immunocompromised individuals, including solid organ transplant (SOT) recipients. Up to 2.65% of…”
Get full text