Search Results - "Smith, B.Douglas"
-
1
Detection of FLT3 Internal Tandem Duplication and D835 Mutations by a Multiplex Polymerase Chain Reaction and Capillary Electrophoresis Assay
Published in The Journal of molecular diagnostics : JMD (01-05-2003)“…FLT3 is a receptor tyrosine kinase that is expressed on early hematopoietic progenitor cells and plays an important role in stem cell survival and…”
Get full text
Journal Article -
2
Low immunosuppressive burden after HLA-matched related or unrelated BMT using posttransplantation cyclophosphamide
Published in Blood (09-03-2017)“…The intensive and prolonged immunosuppressive therapy required to prevent or treat graft-versus-host disease (GVHD) after allogeneic blood or marrow…”
Get full text
Journal Article -
3
Poly(ADP-ribose) Polymerase Inhibitors Sensitize Cancer Cells to Death Receptor-mediated Apoptosis by Enhancing Death Receptor Expression
Published in The Journal of biological chemistry (25-07-2014)“…Recombinant human tumor necrosis factor-α-related apoptosis inducing ligand (TRAIL), agonistic monoclonal antibodies to TRAIL receptors, and small molecule…”
Get full text
Journal Article -
4
4EBP1/c-MYC/PUMA and NF-κB/EGR1/BIM pathways underlie cytotoxicity of mTOR dual inhibitors in malignant lymphoid cells
Published in Blood (02-06-2016)“…The mammalian target of rapamycin (mTOR), a kinase that regulates proliferation and apoptosis, has been extensively evaluated as a therapeutic target in…”
Get full text
Journal Article -
5
Allogeneic hematopoietic stem-cell transplantation with reduced-intensity conditioning in intermediate- or high-risk patients with myelofibrosis with myeloid metaplasia
Published in Blood (15-05-2005)“…A total of 21 patients with myelofibrosis with myeloid metaplasia (MMM), with a median age of 54 years (range, 27-68 years), were prepared with a…”
Get full text
Journal Article -
6
Ribonucleotide reductase: an old target with new potential
Published in Leukemia research (01-12-2003)Get full text
Journal Article -
7
Philadelphia chromosome-negative engraftment after autologous transplantation with granulocyte-macrophage colony-stimulating factor for chronic myeloid leukemia
Published in Biology of blood and marrow transplantation (1999)“…Autologous bone marrow transplantation (BMT) has not been curative in chronic myeloid leukemia (CML), because of the inability to purge CML from the autograft…”
Get full text
Journal Article