Search Results - "Smith, Amanda G."

Photochemical Doping of Protonic Transistors from a Cephalopod Protein by Ordinario, David D, Phan, Long, Van Dyke, Yegor, Nguyen, Tam, Smith, Amanda G, Nguyen, Michael, Mofid, Nikka M, Dao, MyAnh Kaylee, Gorodetsky, Alon A

“…The field of bioelectronics has the potential to revolutionize both fundamental biology and personalized medicine. As such, much research effort has been…”
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Anti-inflammatory activities of novel heat shock protein 90 isoform selective inhibitors in BV-2 microglial cells by Smith, Amanda G, Kliebe, Valentin M, Mishra, Sanket, McCall, Ryan P, Irvine, Megan M, Blagg, Brian S J, Lei, Wei

“…Heat shock protein 90 (Hsp90) is a family of chaperone proteins that consists of four isoforms: Hsp90α, Hsp90β, glucose-regulated protein 94 (Grp94), and tumor…”
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The Effect of Heat Shock Protein 90 Inhibitor on Pain in Cancer Patients: A Systematic Review and Meta-Analysis by Miles, Victoria N, Patel, Roma K, Smith, Amanda G, McCall, Ryan P, Wu, Jun, Lei, Wei

“…Heat shock protein 90 (Hsp90) is a molecular chaperone that plays an essential role in tumor growth. Numerous Hsp90 inhibitors have been discovered and tested…”
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An open-label pilot trial of minocycline in children as a treatment for Angelman syndrome by Grieco, Joseph C, Ciarlone, Stephanie L, Gieron-Korthals, Maria, Schoenberg, Mike R, Smith, Amanda G, Philpot, Rex M, Heussler, Helen S, Banko, Jessica L, Weeber, Edwin J

“…Minocycline, a member of the tetracycline family, has a low risk of adverse effects and an ability to improve behavioral performance in humans with cognitive…”
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Clinical Trials, Potential Mechanisms, and Adverse Effects of Arnica as an Adjunct Medication for Pain Management by Smith, Amanda G., Miles, Victoria N., Holmes, Deltrice T., Chen, Xin, Lei, Wei

“…Arnica has traditionally been used in treating numerous medical conditions, including inflammation and pain. This review aims to summarize the results of…”
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Spatial and temporal silencing of the human maternal UBE3A gene by Daily, Jennifer, Smith, Amanda G, Weeber, Edwin J

“…Abstract Angelman syndrome (AS) is characterized by severe cognitive disruption, seizures, difficulty speaking and ataxia. Nearly all cases are attributed to…”
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An enhanced and rapid method for von Willebrand factor multimer analysis for mechanical circulatory device testing by Smith, Amanda G., McNamee, Antony P., Chan, Chris H. H., Headrick, John, Simmonds, Michael J.

“…Background Von Willebrand factor (VWF) is a critical glycoprotein in hemostasis and is an important factor in diagnosing bleeding disorders. Albeit the…”
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The selective inhibitors for heat shock protein 90 beta reduce the lipopolysaccharide (LPS)‐induced inflammatory response via inhibiting the activation of NF‐κB and ERK MAPK in BV2 microglial cells by Kliebe, Valentin M., Smith, Amanda G., Hanna, Christen, Blagg, Brian S., Lei, Wei

“…Neuroinflammation contributes to several health conditions related to the central nervous system, such as Alzheimer’s Disease and pain. Understanding the…”
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Accelerated Hemocompatibility Testing of Rotary Blood Pumps by McNamee, Antony P., Griffith, Tia A., Smith, Amanda G., Kuck, Lennart, Simmonds, Michael J.

“…Ex vivo hemocompatibility testing is a vital element of preclinical assessment for blood-contacting medical devices. Current approaches are resource intensive;…”
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A YOLO based software for automated detection and analysis of rodent behaviour in the open field arena by Hatton-Jones, Kyle M., Christie, Corey, Griffith, Tia A., Smith, Amanda G., Naghipour, Saba, Robertson, Kai, Russell, Jake S., Peart, Jason N., Headrick, John P., Cox, Amanda J., du Toit, Eugene F.

“…Rodent models are important in mechanistic studies of the physiological and pathophysiological determinants of behaviour. The Open Field Test (OFT) is one of…”
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ENHANCING FLORIDA CLINICAL TRIAL RECRUITMENT IN ALZHEIMER'S DISEASE RESEARCH THROUGH A MOBILE CLINICAL TRIAL UNIT by Smith, Jill S, Morgan, David, Smith, Amanda G

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Identifying biomarkers of dementia prevalent among amnestic mild cognitively impaired ethnic female patients by Grewal, Rinko, Haghighi, Mona, Huang, Shuai, Smith, Amanda G, Cao, Chuanhai, Lin, Xiaoyang, Lee, Daniel C, Teten, Nancy, Hill, Angela M, Selenica, Maj-Linda B

“…There is a need to investigate biomarkers that are indicative of the progression of dementia in ethnic patient populations. The disparity of information in…”
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Venlafaxine for pathological crying after stroke by Smith, Amanda G, Montealegre-Orjuela, Mercedes, Douglas, James E, Jenkins, Elizabeth A

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Analysis of shared heritability in common disorders of the brain by Anttila, Verneri, Bulik-Sullivan, Brendan, Finucane, Hilary K, Walters, Raymond K, Bras, Jose, Duncan, Laramie, Escott-Price, Valentina, Falcone, Guido J, Gormley, Padhraig, Malik, Rainer, Patsopoulos, Nikolaos A, Ripke, Stephan, Wei, Zhi, Yu, Dongmei, Lee, Phil H, Turley, Patrick, Grenier-Boley, Benjamin, Chouraki, Vincent, Kamatani, Yoichiro, Berr, Claudine, Letenneur, Luc, Hannequin, Didier, Amouyel, Philippe, Boland, Anne, Deleuze, Jean-François, Duron, Emmanuelle, Vardarajan, Badri N, Reitz, Christiane, Goate, Alison M, Huentelman, Matthew J, Kamboh, M Ilyas, Larson, Eric B, Rogaeva, Ekaterina, St George-Hyslop, Peter, Hakonarson, Hakon, Kukull, Walter A, Farrer, Lindsay A, Barnes, Lisa L, Beach, Thomas G, Demirci, F Yesim, Head, Elizabeth, Hulette, Christine M, Jicha, Gregory A, Kauwe, John S K, Kaye, Jeffrey A, Leverenz, James B, Levey, Allan I, Lieberman, Andrew P, Pankratz, Vernon S, Poon, Wayne W, Quinn, Joseph F, Saykin, Andrew J, Schneider, Lon S, Smith, Amanda G, Sonnen, Joshua A, Stern, Robert A, Van Deerlin, Vivianna M, Van Eldik, Linda J, Harold, Denise, Russo, Giancarlo, Rubinsztein, David C, Bayer, Anthony, Tsolaki, Magda, Proitsi, Petra, Fox, Nick C, Hampel, Harald, Owen, Michael J, Mead, Simon, Passmore, Peter, Morgan, Kevin, Nöthen, Markus M, Rossor, Martin, Lupton, Michelle K, Hoffmann, Per, Kornhuber, Johannes, Lawlor, Brian, McQuillin, Andrew, Al-Chalabi, Ammar, Bis, Joshua C, Ruiz, Agustin, Boada, Mercè, Seshadri, Sudha, Beiser, Alexa, Rice, Kenneth, van der Lee, Sven J, De Jager, Philip L, Geschwind, Daniel H, Riemenschneider, Matthias, Riedel-Heller, Steffi, Rotter, Jerome I, Ransmayr, Gerhard, Hyman, Bradley T, Cruchaga, Carlos, Alegret, Montserrat, Winsvold, Bendik, Palta, Priit, Farh, Kai-How, Cuenca-Leon, Ester, Furlotte, Nicholas, Kurth, Tobias

“…Disorders of the brain can exhibit considerable epidemiological comorbidity and often share symptoms, provoking debate about their etiologic overlap. We…”
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Behavioral problems in dementia: Strategies for pharmacologic and nonpharmacologic management by Smith, Amanda G.

“…Behavioral disturbances in Alzheimer's disease and related disorders are common throughout all stages of these dementing illnesses. They are a major source of…”
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Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study by Reiman, Eric M., Arboleda-Velasquez, Joseph F., Quiroz, Yakeel T., Huentelman, Matthew J., Beach, Thomas G., Caselli, Richard J., Chen, Yinghua, Su, Yi, Myers, Amanda J., Hardy, John, Paul Vonsattel, Jean, Younkin, Steven G., Bennett, David A., De Jager, Philip L., Larson, Eric B., Crane, Paul K., Keene, C. Dirk, Kamboh, M. Ilyas, Kofler, Julia K., Duque, Linda, Gilbert, John R., Gwirtsman, Harry E., Buxbaum, Joseph D., Dickson, Dennis W., Frosch, Matthew P., Ghetti, Bernardino F., Lunetta, Kathryn L., Wang, Li-San, Hyman, Bradley T., Kukull, Walter A., Foroud, Tatiana, Haines, Jonathan L., Mayeux, Richard P., Pericak-Vance, Margaret A., Schneider, Julie A., Trojanowski, John Q., Farrer, Lindsay A., Schellenberg, Gerard D., Beecham, Gary W., Montine, Thomas J., Jun, Gyungah R.

“…Each additional copy of the apolipoprotein E4 (APOE4) allele is associated with a higher risk of Alzheimer’s dementia, while the APOE2 allele is associated…”
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Topiramate Overdose: A Case Report and Literature Review by Smith, Amanda G, Brauer, Heidi R, Catalano, Glenn, Catalano, Maria C

“…Topiramate is a medication introduced in the United States in 1997 for the treatment of epilepsy. Studies are currently underway to determine its effectiveness…”
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Associations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study by Østergaard, Søren D, Mukherjee, Shubhabrata, Sharp, Stephen J, Proitsi, Petroula, Lotta, Luca A, Day, Felix, Perry, John R B, Boehme, Kevin L, Walter, Stefan, Kauwe, John S, Gibbons, Laura E, Larson, Eric B, Powell, John F, Langenberg, Claudia, Crane, Paul K, Wareham, Nicholas J, Scott, Robert A

“…Potentially modifiable risk factors including obesity, diabetes, hypertension, and smoking are associated with Alzheimer disease (AD) and represent promising…”
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P3‐028: UTILIZING A MOBILE CLINICAL TRIAL UNIT TO ENHANCE RECRUITMENT IN PREVENTION TRIALS FOR ALZHEIMER'S DISEASE by Smith, Amanda G., Smith, Jill S., Morgan, Dave

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UTILIZING A MOBILE CLINICAL TRIAL UNIT TO ENHANCE RECRUITMENT IN PREVENTION TRIALS FOR ALZHEIMER’S DISEASE by Smith, Amanda G., Smith, Jill S., Morgan, Dave

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