Search Results - "Smith, Alias"
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Downstream of mutant KRAS, the transcription regulator YAP is essential for neoplastic progression to pancreatic ductal adenocarcinoma
Published in Science signaling (06-05-2014)“…Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer with poor survival rates and frequently carries oncogenic KRAS mutation. However, KRAS has thus…”
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Journal Article -
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The minimal kinome of Giardia lamblia illuminates early kinase evolution and unique parasite biology
Published in Genome Biology (25-07-2011)“…The major human intestinal pathogen Giardia lamblia is a very early branching eukaryote with a minimal genome of broad evolutionary and biological interest. To…”
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Journal Article -
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Gene expression in the unicellular eukaryote Trichomonas vaginalis
Published in Research in microbiology (01-07-2011)“…Control of gene expression is essential to the survival of an organism. Here, we review the current state of gene expression research in Trichomonas vaginalis,…”
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Draft Genome Sequence of the Sexually Transmitted Pathogen Trichomonas vaginalis
Published in Science (American Association for the Advancement of Science) (12-01-2007)“…We describe the genome sequence of the protist Trichomonas vaginalis, a sexually transmitted human pathogen. Repeats and transposable elements comprise about…”
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Journal Article -
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Novel Core Promoter Elements and a Cognate Transcription Factor in the Divergent Unicellular Eukaryote Trichomonas vaginalis
Published in Molecular and Cellular Biology (01-04-2011)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Giardia lamblia Nek1 and Nek2 kinases affect mitosis and excystation
Published in International journal for parasitology (01-04-2012)“…[Display omitted] ► The first report of functional analysis of two Giardia lamblia Nek kinases. ► Both GlNeks have dynamic re-localisation during the cell…”
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Journal Article -
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Mining the Giardia genome and proteome for conserved and unique basal body proteins
Published in International journal for parasitology (15-08-2011)“…[Display omitted] ► Sixty-five homologs of conserved basal body proteins were identified in Giardia. ► Thirteen new basal body proteins were immunolocalised in…”
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Journal Article -
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Trichomonas vaginalis initiator binding protein (IBP39) and RNA polymerase II large subunit carboxy terminal domain interaction
Published in Molecular and biochemical parasitology (01-11-2006)“…The core promoter that directs RNA polymerase to the start of transcription in the protist Trichomonas vaginalis is an initiator (Inr) element recognized by…”
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Identification and characterization of novel core promoter elements and a new transcription factor in Trichomonas vaginalis
Published 01-01-2009“…The molecular mechanisms involved in regulating eukaryotic gene expression have been primarily studied in fungi, plants and animals. By comparison, far less is…”
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Dissertation -
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Identification and characterization of novel core promoter elements and a new transcription factor in Trichomonas vaginalis
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Dissertation