Search Results - "Smit, W. J."
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Long-term analysis of the efficacy and tolerability of sorafenib in advanced radio-iodine refractory differentiated thyroid carcinoma: final results of a phase II trial
Published in European journal of endocrinology (01-11-2012)“…Objective We conducted a prospective phase II clinical trial to determine the efficacy of sorafenib in patients with advanced radio-iodine refractory…”
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Serum microRNA-1 and microRNA-133a levels reflect myocardial steatosis in uncomplicated type 2 diabetes
Published in Scientific reports (03-03-2017)“…Using in vitro , in vivo and patient-based approaches, we investigated the potential of circulating microRNAs (miRNAs) as surrogate biomarkers of myocardial…”
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3
Increased Urinary Excretion of 3-Methoxytyramine in Patients with Head and Neck Paragangliomas
Published in The journal of clinical endocrinology and metabolism (01-01-2010)“…Context: Patients with head-and-neck paragangliomas (HNPGL) are regularly screened for catecholamine excess. The clinical relevance of increased urinary…”
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4
Observation Alone after Transsphenoidal Surgery for Nonfunctioning Pituitary Macroadenoma
Published in The journal of clinical endocrinology and metabolism (01-05-2006)“…Objective: Transsphenoidal surgery is the treatment of choice for nonfunctioning pituitary macroadenomas (NFMA). In this study we evaluated the long-term…”
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5
New treatment modalities in advanced thyroid cancer
Published in Annals of oncology (01-01-2012)“…Thyroid cancer is a heterogeneous disease that is classified into differentiated thyroid carcinoma (DTC), undifferentiated/anaplastic thyroid carcinoma (ATC)…”
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Endoscopic transsphenoidal pituitary surgery: a good and safe primary treatment option for Cushing's disease, even in case of macroadenomas or invasive adenomas
Published in European journal of endocrinology (01-09-2013)“…ContextAlthough the endoscopic technique of transsphenoidal pituitary surgery (TS) has been widely adopted, reports on its results in Cushing's disease (CD)…”
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Cost-Effectiveness of FDG-PET/CT for Cytologically Indeterminate Thyroid Nodules: A Decision Analytic Approach
Published in The journal of clinical endocrinology and metabolism (01-09-2014)“…Context: Patients with thyroid nodules of indeterminate cytology undergo diagnostic surgery according to current guidelines. In 75% of patients, the nodule is…”
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Quality of Life in Patients after Long-Term Biochemical Cure of Cushing’s Disease
Published in The journal of clinical endocrinology and metabolism (01-06-2005)“…To evaluate the long-term impact of cured Cushing’s disease on subjective well-being, we assessed quality of life by validated health-related questionnaires in…”
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Progression of acromegalic arthropathy despite long-term biochemical control: a prospective, radiological study
Published in European journal of endocrinology (01-08-2012)“…ObjectiveArthropathy is an invalidating complication of acromegaly, of which the prognosis and determinants are currently unknown in treated acromegaly…”
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10
Clinical outcomes after estimated versus calculated activity of radioiodine for the treatment of hyperthyroidism: systematic review and meta-analysis
Published in European journal of endocrinology (01-11-2009)“…BackgroundDespite the long experience with radioiodine for hyperthyroidism, controversy remains regarding the optimal method to determine the activity that is…”
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The Type 2 Deiodinase ORFa-Gly3Asp Polymorphism (rs12885300) Influences the Set Point of the Hypothalamus-Pituitary-Thyroid Axis in Patients Treated for Differentiated Thyroid Carcinoma
Published in The journal of clinical endocrinology and metabolism (01-09-2011)“…Context: Iodothyronine deiodinases D1, D2, and D3 play an important role in synthesis and degradation of T3. The relationship between serum TSH and free T4…”
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Ectopic Fat and Insulin Resistance: Pathophysiology and Effect of Diet and Lifestyle Interventions
Published in International Journal of Endocrinology (01-01-2012)“…The storage of triglyceride (TG) droplets in nonadipose tissues is called ectopic fat storage. Ectopic fat is associated with insulin resistance and type 2…”
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High levels of procoagulant factors mediate the association between free thyroxine and the risk of venous thrombosis: the MEGA study
Published in Journal of thrombosis and haemostasis (01-06-2014)“…Summary Background Thyroid hormone affects the coagulation system, but its effect on clinical disease is not clear. We determined the associations of levels of…”
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Impact of the Exon 3-Deleted Growth Hormone (GH) Receptor Polymorphism on Baseline Height and the Growth Response to Recombinant Human GH Therapy in GH-Deficient (GHD) and Non-GHD Children with Short Stature: A Systematic Review and Meta-Analysis
Published in The journal of clinical endocrinology and metabolism (01-10-2009)“…Context: The exon-3 deleted GH receptor (GHRd3) polymorphism is associated with an increased growth response to recombinant human GH (rhGH) therapy in some,…”
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The natural course of non-functioning pituitary macroadenomas
Published in European journal of endocrinology (01-02-2007)“…Objective: The natural history of non-functioning pituitary macroadenomas (NFMA) has not been completely elucidated. Therefore, we evaluated pituitary…”
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Distinct effects of pioglitazone and metformin on circulating sclerostin and biochemical markers of bone turnover in men with type 2 diabetes mellitus
Published in European journal of endocrinology (01-04-2012)“…ObjectivePatients with type 2 diabetes mellitus (T2DM) have an increased risk of fractures and thiazolidinediones (TZDs) increase this risk. TZDs stimulate the…”
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Pioglitazone Compared with Metformin Increases Pericardial Fat Volume in Patients with Type 2 Diabetes Mellitus
Published in The journal of clinical endocrinology and metabolism (01-01-2010)“…Context: Peroxisome proliferator-activated receptor-γ agonists are involved in fat cell differentiation. Objective: The objective of the study was to…”
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Quality of Life Is Decreased after Treatment for Nonfunctioning Pituitary Macroadenoma
Published in The journal of clinical endocrinology and metabolism (01-09-2006)“…Objective: Although a reduced quality of life (QoL) has been reported after long-term cure of functioning pituitary adenomas, the effect of successful…”
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Low prevalence of hypopituitarism after traumatic brain injury: a multicenter study
Published in European journal of endocrinology (01-08-2011)“…ObjectiveHypopituitarism after traumatic brain injury (TBI) is considered to be a prevalent condition. However, prevalence rates differ considerably among…”
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Vascular Health in Patients in Remission of Cushing's Syndrome Is Comparable With That in BMI-Matched Controls
Published in The journal of clinical endocrinology and metabolism (01-11-2016)“…Context: In active Cushing's syndrome (CS), patients suffer from endothelial dysfunction and premature atherosclerosis. However, it is uncertain to what extent…”
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