Search Results - "Smit, Johannes W A"

Insulin resistance and risk of incident cardiovascular events in adults without diabetes: meta-analysis by Gast, Karin B, Tjeerdema, Nathanja, Stijnen, Theo, Smit, Johannes W A, Dekkers, Olaf M

“…Glucose, insulin and Homeostasis Model Assessment Insulin Resistance (HOMA-IR) are markers of insulin resistance. The objective of this study is to compare…”
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Sorafenib in radioactive iodine-refractory, locally advanced or metastatic differentiated thyroid cancer: a randomised, double-blind, phase 3 trial by Brose, Marcia S, Dr, Nutting, Christopher M, Prof, Jarzab, Barbara, Prof, Elisei, Rossella, Prof, Siena, Salvatore, MD, Bastholt, Lars, MD, de la Fouchardiere, Christelle, MD, Pacini, Furio, Prof, Paschke, Ralf, Prof, Shong, Young Kee, Prof, Sherman, Steven I, Prof, Smit, Johannes W A, Prof, Chung, John, MD, Kappeler, Christian, PhD, Peña, Carol, PhD, Molnár, István, MD, Schlumberger, Martin J, Prof

“…Summary Background Patients with radioactive iodine (131 I)-refractory locally advanced or metastatic differentiated thyroid cancer have a poor prognosis…”
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Effect of PTEN inactivating germline mutations on innate immune cell function and thyroid cancer-induced macrophages in patients with PTEN hamartoma tumor syndrome by Sloot, Yvette J. E., Rabold, Katrin, Netea, Mihai G., Smit, Johannes W. A., Hoogerbrugge, Nicoline, Netea-Maier, Romana T.

“…PTEN hamartoma tumor syndrome (PHTS) is caused by inactivating germline PTEN mutations with subsequent activation of Akt-mTOR signaling, leading to an…”
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Pituitary Dysfunction in Adult Patients after Cranial Radiotherapy: Systematic Review and Meta-Analysis by Appelman-Dijkstra, Natasha M, Kokshoorn, Nieke E, Dekkers, Olaf M, Neelis, Karen J, Biermasz, Nienke R, Romijn, Johannes A, Smit, Johannes W. A, Pereira, Alberto M

“…Context: Cranial radiotherapy is an important cause of hypopituitarism. The prevalence of hypopituitarism varies considerably between studies. Objective: We…”
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Infection with Soil-Transmitted Helminths Is Associated with Increased Insulin Sensitivity by Wiria, Aprilianto E, Hamid, Firdaus, Wammes, Linda J, Prasetyani, Margaretta A, Dekkers, Olaf M, May, Linda, Kaisar, Maria M M, Verweij, Jaco J, Guigas, Bruno, Partono, Felix, Sartono, Erliyani, Supali, Taniawati, Yazdanbakhsh, Maria, Smit, Johannes W A

“…Given that helminth infections have been shown to improve insulin sensitivity in animal studies, which may be explained by beneficial effects on energy balance…”
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Altered Myocardial Substrate Metabolism and Decreased Diastolic Function in Nonischemic Human Diabetic Cardiomyopathy: Studies With Cardiac Positron Emission Tomography and Magnetic Resonance Imaging by RIJZEWIJK, Luuk J, VAN DER MEER, Rutger W, LAMMERTSMA, Adriaan A, SMIT, Johannes W. A, DIAMANT, Michaela, LAMB, Hildo J, DE JONG, Hugo W. A. M, LUBBERINK, Mark, ROMIJN, Johannes A, BAX, Jeroen J, DE ROOS, Albert, TWISK, Jos W, HEINE, Robert J

“…This study was designed to evaluate myocardial substrate and high-energy phosphate (HEP) metabolism in asymptomatic men with well-controlled, uncomplicated…”
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Findings from Left Ventricular Strain and Strain Rate Imaging in Asymptomatic Patients With Type 2 Diabetes Mellitus by Ng, Arnold C.T., MBBS, Delgado, Victoria, MD, Bertini, Matteo, MD, van der Meer, Rutger W., MD, Rijzewijk, Luuk J., MD, Shanks, Miriam, MD, Nucifora, Gaetano, MD, Smit, Johannes W.A., MD, PhD, Diamant, Michaela, MD, PhD, Romijn, Johannes A., MD, PhD, de Roos, Albert, MD, PhD, Leung, Dominic Y., MBBS, PhD, Lamb, Hildo J., MD, PhD, Bax, Jeroen J., MD, PhD

“…Regional left ventricular (LV) myocardial functional changes in early diabetic cardiomyopathy have not been well documented. LV multidirectional strain and…”
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Coping Strategies in Patients after Treatment for Functioning or Nonfunctioning Pituitary Adenomas by Tiemensma, Jitske, Kaptein, Adrian A, Pereira, Alberto M, Smit, Johannes W. A, Romijn, Johannes A, Biermasz, Nienke R

“…Patients with treated pituitary adenomas display different and less effective coping strategies compared with the normal population. Context and Objective:…”
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Phenotyping diabetic cardiomyopathy in Europeans and South Asians by Paiman, Elisabeth H M, van Eyk, Huub J, Bizino, Maurice B, Dekkers, Ilona A, de Heer, Paul, Smit, Johannes W A, Jazet, Ingrid M, Lamb, Hildo J

“…The pathogenesis and cardiovascular impact of type 2 diabetes (T2D) may be different in South Asians compared with other ethnic groups. The phenotypic…”
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Hypopituitarism following traumatic brain injury: prevalence is affected by the use of different dynamic tests and different normal values by Kokshoorn, Nieke E, Wassenaar, Moniek J E, Biermasz, Nienke R, Roelfsema, Ferdinand, Smit, Johannes W A, Romijn, Johannes A, Pereira, Alberto M

“…ObjectiveTraumatic brain injury (TBI) has emerged as an important cause of hypopituitarism. However, considerable variations in the prevalence of…”
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The Influence of Energy Depletion by Metformin or Hypocaloric Diet on Thyroid Iodine Uptake in Healthy Volunteers: a Randomized Trial by Sloot, Yvette J. E., Janssen, Marcel J. R., van Herwaarden, Antonius E., Peeters, Robin P., Netea-Maier, Romana T., Smit, Johannes W. A.

“…Sufficient thyroid iodine uptake is needed to ensure effective radioactive iodine (RAI) treatment, which is mediated by the sodium-iodide symporter (NIS)…”
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Cardiac dysfunction is reversed upon successful treatment of Cushing's syndrome by Pereira, Alberto M, Delgado, Victoria, Romijn, Johannes A, Smit, Johannes W A, Bax, Jeroen J, Feelders, Richard A

“…ObjectiveIn patients with active Cushing's syndrome (CS), cardiac structural and functional changes have been described in a limited number of patients. It is…”
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Relationship between carotid intima media thickness and helminth infections on Flores Island, Indonesia by Wiria, Aprilianto Eddy, Wammes, Linda J, Hamid, Firdaus, Dekkers, Olaf M, Prasetyani, Margaretta A, May, Linda, Kaisar, Maria M M, Verweij, Jaco J, Tamsma, Jouke T, Partono, Felix, Sartono, Erliyani, Supali, Taniawati, Yazdanbakhsh, Maria, Smit, Johannes W A

“…To examine the association between helminth infections and atherosclerosis. Chronic helminth infection, which can lead to poor nutritional status and…”
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Metabolic changes in tumor cells and tumor-associated macrophages: A mutual relationship by Netea-Maier, Romana T., Smit, Johannes W.A., Netea, Mihai G.

“…In order to adapt to the reduced availability of nutrients and oxygen in the tumor microenvironment and the increased requirements of energy and building…”
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Roux-en-Y gastric bypass and calorie restriction induce comparable time-dependent effects on thyroid hormone function tests in obese female subjects by Lips, Mirjam A, Pijl, Hanno, van Klinken, Jan B, de Groot, Gerrit H, Janssen, Ignace M, Van Ramshorst, Bert, Van Wagensveld, Bart A, Swank, Dingeman J, Van Dielen, Fracois, Smit, Johannes W A

“…ObjectiveObesity and weight loss influence thyroid hormone physiology. The effects of weight loss by calorie restriction vs Roux-en-Y gastric bypass (RYGB) in…”
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Effects of Hepatic Triglyceride Content on Myocardial Metabolism in Type 2 Diabetes by Rijzewijk, Luuk J., MD, Jonker, Jacqueline T., MD, van der Meer, Rutger W., MD, PhD, Lubberink, Mark, PhD, de Jong, Hugo W., PhD, Romijn, Johannes A., MD, PhD, Bax, Jeroen J., MD, PhD, de Roos, Albert, MD, PhD, Heine, Robert J., MD, PhD, Twisk, Jos W., MD, PhD, Windhorst, Albert D., PhD, Lammertsma, Adriaan A., PhD, Smit, Johannes W.A., MD, PhD, Diamant, Michaela, MD, PhD, Lamb, Hildo J., MD, PhD

“…Objectives The purpose of this study was to investigate the relationship between hepatic triglyceride content and both myocardial function and metabolism in…”
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Proteomic analysis in type 2 diabetes patients before and after a very low calorie diet reveals potential disease state and intervention specific biomarkers by Sleddering, Maria A, Markvoort, Albert J, Dharuri, Harish K, Jeyakar, Skhandhan, Snel, Marieke, Juhasz, Peter, Lynch, Moira, Hines, Wade, Li, Xiaohong, Jazet, Ingrid M, Adourian, Aram, Hilbers, Peter A J, Smit, Johannes W A, Van Dijk, Ko Willems

“…Very low calorie diets (VLCD) with and without exercise programs lead to major metabolic improvements in obese type 2 diabetes patients. The mechanisms…”
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GH replacement therapy in elderly GH-deficient patients: a systematic review by Kokshoorn, Nieke E, Biermasz, Nienke R, Roelfsema, Ferdinand, Smit, Johannes W A, Pereira, Alberto M, Romijn, Johannes A

“…ContextRecombinant human GH (rhGH) is prescribed for the treatment of adults with GH deficiency (GHD). However, conflicting data are available on the efficacy…”
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Niacin Reduces Atherosclerosis Development in APOE3Leiden.CETP Mice Mainly by Reducing NonHDL-Cholesterol by Kühnast, Susan, Louwe, Mieke C, Heemskerk, Mattijs M, Pieterman, Elsbet J, van Klinken, Jan B, van den Berg, Sjoerd A A, Smit, Johannes W A, Havekes, Louis M, Rensen, Patrick C N, van der Hoorn, José W A, Princen, Hans M G, Jukema, J Wouter

“…Niacin potently lowers triglycerides, mildly decreases LDL-cholesterol, and largely increases HDL-cholesterol. Despite evidence for an atheroprotective effect…”
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Physiological Thyroid Hormone Levels Regulate Numerous Skeletal Muscle Transcripts by Visser, W. Edward, Heemstra, Karen A., Swagemakers, Sigrid M. A., Özgür, Zeliha, Corssmit, Eleonora P., Burggraaf, Jacobus, van Ijcken, Wilfred F. J., van der Spek, Peter J., Smit, Johannes W. A., Visser, Theo J.

“…Context: Skeletal muscle is an important target tissue for thyroid hormone (TH). It is currently unknown which genes are regulated by physiological TH levels…”
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