Search Results - "Smit, Johannes"
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1
Metabolic changes in tumor cells and tumor-associated macrophages: A mutual relationship
Published in Cancer letters (28-01-2018)“…In order to adapt to the reduced availability of nutrients and oxygen in the tumor microenvironment and the increased requirements of energy and building…”
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2
Insulin resistance and risk of incident cardiovascular events in adults without diabetes: meta-analysis
Published in PloS one (28-12-2012)“…Glucose, insulin and Homeostasis Model Assessment Insulin Resistance (HOMA-IR) are markers of insulin resistance. The objective of this study is to compare…”
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3
Myocardial Steatosis Is an Independent Predictor of Diastolic Dysfunction in Type 2 Diabetes Mellitus
Published in Journal of the American College of Cardiology (25-11-2008)“…Objectives The purpose of this study was to compare myocardial triglyceride content and function between patients with uncomplicated type 2 diabetes mellitus…”
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4
Teologie en Kerkreg: Wat word van die Heilige Gees in ons teologie en in die Kerkreg?
Published in In die skriflig : tydskrif van die Gereformeerde Teologiese Vereniging (24-05-2024)“…Theology and Church Polity: What becomes of the Holy Spirit in our theology and Church Polity? Currently, a shift in theological training is taking place in…”
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5
Sorafenib in radioactive iodine-refractory, locally advanced or metastatic differentiated thyroid cancer: a randomised, double-blind, phase 3 trial
Published in The Lancet (British edition) (26-07-2014)“…Summary Background Patients with radioactive iodine (131 I)-refractory locally advanced or metastatic differentiated thyroid cancer have a poor prognosis…”
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6
Altered Myocardial Substrate Metabolism and Decreased Diastolic Function in Nonischemic Human Diabetic Cardiomyopathy: Studies With Cardiac Positron Emission Tomography and Magnetic Resonance Imaging
Published in Journal of the American College of Cardiology (13-10-2009)“…This study was designed to evaluate myocardial substrate and high-energy phosphate (HEP) metabolism in asymptomatic men with well-controlled, uncomplicated…”
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7
Risk of Hypothyroidism following Hemithyroidectomy: Systematic Review and Meta-Analysis of Prognostic Studies
Published in The journal of clinical endocrinology and metabolism (01-07-2012)“…Context: The reported risk of hypothyroidism after hemithyroidectomy shows considerable heterogeneity in literature. Objective: The aim of this systematic…”
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8
Association Between Levothyroxine Treatment and Thyroid-Related Symptoms Among Adults Aged 80 Years and Older With Subclinical Hypothyroidism
Published in JAMA : the journal of the American Medical Association (26-11-2019)“…IMPORTANCE: It is unclear whether levothyroxine treatment provides clinically important benefits in adults aged 80 years and older with subclinical…”
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9
Findings from Left Ventricular Strain and Strain Rate Imaging in Asymptomatic Patients With Type 2 Diabetes Mellitus
Published in The American journal of cardiology (15-11-2009)“…Regional left ventricular (LV) myocardial functional changes in early diabetic cardiomyopathy have not been well documented. LV multidirectional strain and…”
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10
Effect of PTEN inactivating germline mutations on innate immune cell function and thyroid cancer-induced macrophages in patients with PTEN hamartoma tumor syndrome
Published in Oncogene (01-05-2019)“…PTEN hamartoma tumor syndrome (PHTS) is caused by inactivating germline PTEN mutations with subsequent activation of Akt-mTOR signaling, leading to an…”
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Infection with Soil-Transmitted Helminths Is Associated with Increased Insulin Sensitivity
Published in PloS one (10-06-2015)“…Given that helminth infections have been shown to improve insulin sensitivity in animal studies, which may be explained by beneficial effects on energy balance…”
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Prolonged Caloric Restriction in Obese Patients With Type 2 Diabetes Mellitus Decreases Myocardial Triglyceride Content and Improves Myocardial Function
Published in Journal of the American College of Cardiology (16-09-2008)“…Prolonged Caloric Restriction in Obese Patients With Type 2 Diabetes Mellitus Decreases Myocardial Triglyceride Content and Improves Myocardial Function…”
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13
Serious Games for Mental Health: Are They Accessible, Feasible, and Effective? A Systematic Review and Meta-analysis
Published in Frontiers in psychiatry (18-01-2017)“…The development and use of serious games for mental health disorders are on the rise. Yet, little is known about the impact of these games on clinical mental…”
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14
Modulation of inflammation by autophagy: Consequences for human disease
Published in Autophagy (01-01-2016)“…Autophagy and inflammation are 2 fundamental biological processes involved in both physiological and pathological conditions. Through its crucial role in…”
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15
Safety planning-type interventions for suicide prevention: meta-analysis
Published in British journal of psychiatry (01-08-2021)“…Safety planning-type interventions (SPTIs) for patients at risk of suicide are often used in clinical practice, but it is unclear whether these interventions…”
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16
Longitudinal Association Between Depression and Inflammatory Markers: Results From the Netherlands Study of Depression and Anxiety
Published in Biological psychiatry (1969) (15-05-2019)“…While cross-sectional associations of inflammatory markers interleukin-6 (IL-6) and C-reactive protein with major depressive disorder are well established,…”
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Pituitary Dysfunction in Adult Patients after Cranial Radiotherapy: Systematic Review and Meta-Analysis
Published in The journal of clinical endocrinology and metabolism (01-08-2011)“…Context: Cranial radiotherapy is an important cause of hypopituitarism. The prevalence of hypopituitarism varies considerably between studies. Objective: We…”
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Pioglitazone Improves Cardiac Function and Alters Myocardial Substrate Metabolism Without Affecting Cardiac Triglyceride Accumulation and High-Energy Phosphate Metabolism in Patients With Well-Controlled Type 2 Diabetes Mellitus
Published in Circulation (New York, N.Y.) (21-04-2009)“…Cardiac disease is the leading cause of mortality in type 2 diabetes mellitus (T2DM). Pioglitazone has been associated with improved cardiac outcome but also…”
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19
Towards Personalized TSH Reference Ranges: A Genetic and Population-Based Approach in Three Independent Cohorts
Published in Thyroid (New York, N.Y.) (01-08-2024)“…Serum thyroid-stimulating hormone (TSH) measurement is the diagnostic cornerstone for primary thyroid dysfunction. There is high inter-individual but limited…”
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Effectiveness and treatment moderators of internet interventions for adult problem drinking: An individual patient data meta-analysis of 19 randomised controlled trials
Published in PLoS medicine (18-12-2018)“…Face-to-face brief interventions for problem drinking are effective, but they have found limited implementation in routine care and the community…”
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