Search Results - "Smit, Arian F"
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RepeatModeler2 for automated genomic discovery of transposable element families
Published in Proceedings of the National Academy of Sciences - PNAS (28-04-2020)“…The accelerating pace of genome sequencing throughout the tree of life is driving the need for improved unsupervised annotation of genome components such as…”
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The Dfam community resource of transposable element families, sequence models, and genome annotations
Published in Mobile DNA (12-01-2021)“…Dfam is an open access database of repetitive DNA families, sequence models, and genome annotations. The 3.0-3.3 releases of Dfam ( https://dfam.org )…”
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Analysis of Genetic Inheritance in a Family Quartet by Whole-Genome Sequencing
Published in Science (American Association for the Advancement of Science) (30-04-2010)“…We analyzed the whole-genome sequences of a family of four, consisting of two siblings and their parents. Family-based sequencing allowed us to delineate…”
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Dfam: a database of repetitive DNA based on profile hidden Markov models
Published in Nucleic acids research (01-01-2013)“…We present a database of repetitive DNA elements, called Dfam (http://dfam.janelia.org). Many genomes contain a large fraction of repetitive DNA, much of which…”
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The genome of a songbird
Published in Nature (London) (01-04-2010)“…The zebra finch is an important model organism in several fields with unique relevance to human neuroscience. Like other songbirds, the zebra finch…”
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Chromosomal Haplotypes by Genetic Phasing of Human Families
Published in American journal of human genetics (09-09-2011)“…Assignment of alleles to haplotypes for nearly all the variants on all chromosomes can be performed by genetic analysis of a nuclear family with three or more…”
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Functional noncoding sequences derived from SINEs in the mammalian genome
Published in Genome Research (01-07-2006)“…Recent comparative analyses of mammalian sequences have revealed that a large number of nonprotein-coding genomic regions are under strong selective…”
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Mobile DNA in Old World Monkeys: A Glimpse Through the Rhesus Macaque Genome
Published in Science (American Association for the Advancement of Science) (13-04-2007)“…The completion of the draft sequence of the rhesus macaque genome allowed us to study the genomic composition and evolution of transposable elements in this…”
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Discovery of a new repeat family in the Callithrix jacchus genome
Published in Genome research (01-05-2016)“…We identified a novel repeat family, termed Platy-1, in the Callithrix jacchus (common marmoset) genome that arose around the time of the divergence of…”
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The Dfam database of repetitive DNA families
Published in Nucleic acids research (04-01-2016)“…Repetitive DNA, especially that due to transposable elements (TEs), makes up a large fraction of many genomes. Dfam is an open access database of families of…”
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Evolution and gene capture in ancient endogenous retroviruses - insights from the crocodilian genomes
Published in Retrovirology (12-12-2014)“…Crocodilians are thought to be hosts to a diverse and divergent complement of endogenous retroviruses (ERVs) but a comprehensive investigation is yet to be…”
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The UCSC Genome Browser database: 2015 update
Published in Nucleic acids research (28-01-2015)“…Launched in 2001 to showcase the draft human genome assembly, the UCSC Genome Browser database (http://genome.ucsc.edu) and associated tools continue to grow,…”
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A comparative genomics multitool for scientific discovery and conservation
Published in Nature (London) (12-11-2020)“…The Zoonomia Project is investigating the genomics of shared and specialized traits in eutherian mammals. Here we provide genome assemblies for 131 species, of…”
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A third approach to gene prediction suggests thousands of additional human transcribed regions
Published in PLoS computational biology (01-03-2006)“…The identification and characterization of the complete ensemble of genes is a main goal of deciphering the digital information stored in the human genome…”
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Three crocodilian genomes reveal ancestral patterns of evolution among archosaurs
Published in Science (American Association for the Advancement of Science) (12-12-2014)“…To provide context for the diversification of archosaurs--the group that includes crocodilians, dinosaurs, and birds--we generated draft genomes of three…”
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Methodologies for the De novo Discovery of Transposable Element Families
Published in Genes (17-04-2022)“…The discovery and characterization of transposable element (TE) families are crucial tasks in the process of genome annotation. Careful curation of TE…”
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The transposable element-rich genome of the cereal pest Sitophilus oryzae
Published in BMC biology (09-11-2021)“…The rice weevil Sitophilus oryzae is one of the most important agricultural pests, causing extensive damage to cereal in fields and to stored grains. S. oryzae…”
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Realistic artificial DNA sequences as negative controls for computational genomics
Published in Nucleic acids research (08-07-2014)“…A common practice in computational genomic analysis is to use a set of 'background' sequences as negative controls for evaluating the false-positive rates of…”
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Chiropterans Are a Hotspot for Horizontal Transfer of DNA Transposons in Mammalia
Published in Molecular biology and evolution (02-05-2023)“…Abstract Horizontal transfer of transposable elements (TEs) is an important mechanism contributing to genetic diversity and innovation. Bats (order Chiroptera)…”
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From telomere to telomere: The transcriptional and epigenetic state of human repeat elements
Published in Science (American Association for the Advancement of Science) (01-04-2022)“…Mobile elements and repetitive genomic regions are sources of lineage-specific genomic innovation and uniquely fingerprint individual genomes. Comprehensive…”
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