Search Results - "Smirnikhina, S A"

Animal models for researching approaches to therapy of Duchenne muscular dystrophy by Zaynitdinova, M. I., Lavrov, A. V., Smirnikhina, S. A.

“…Duchenne muscular dystrophy (DMD) is a relatively widespread genetic disease which develops as a result of a mutation in the gene DMD encoding dystrophin. In…”
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Stages of research and development of therapeutic approaches for Duchenne myodystrophy. Part II: etiotropic approaches by Kochergin-Nikitskiy, K. S., Smirnikhina, S. A., Lavrov, A. V.

“…Duchenne muscular dystrophy is one of the most common inherited muscular dystrophies. The cause of this disease with an X‑linked recessive type of inheritance…”
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The Choice of a Donor Molecule in Genome Editing Experiments in Animal Cells by Volodina, O. V., Smirnikhina, S. A.

“…— Genome editing is a powerful tool that allows study of the properties of genes or changes to be made to the genetic sequence. Programmable nucleases that can…”
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TIRR: a potential front runner in HDR race−hypotheses and perspectives by Anuchina, A. A., Lavrov, A. V., Smirnikhina, S. A.

“…The majority of CRISPR-Cas9 methods for mutations correction are oriented on gene editing through homologous recombination that is normally restrained by…”
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Stages of research and development of therapeutic approaches for Duchenne myodystrophy. Part I: the period before etiotropic approaches introduction by Kochergin-Nikitskiy, K. S., Smirnikhina, S. A., Lavrov, A. V.

“…Duchenne muscular dystrophy is one of the most common inherited muscular dystrophies. The cause of this disease with an X‑linked recessive type of inheritance…”
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Correction to: TIRR: a potential front runner in HDR race–hypotheses and perspectives by Anuchina, A. A., Lavrov, A. V., Smirnikhina, S. A.

“…The Acknowledgment text has been updated…”
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Dioxidine-Induced Changes in Genome-Wide DNA Methylation in a Culture of Peripheral Blood Lymphocytes by Smirnikhina, S. A., Voronina, E. S., Lavrov, A. V., Bochkov, N. P.

“…We studied the effect of dioxidine on genome-wide methylation in short-term cultures of peripheral blood lymphocytes derived from healthy donors. Methylation…”
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Generation of two iPSC lines from patient with Mucopolysaccharidosis IV B type and autosomal recessive non-syndromic hearing loss 12 by Panchuk, I.O., Grigorieva, O.V., Kondrateva, E.V., Kurshakova, E.V., Tabakov, VYu, Bychkov, I.O., Zakharova, EYu, Orlova, M.D., Voronina, E.S., Pozhitnova, V.O., Lavrov, A.V., Smirnikhina, S.A., Kutsev, S.I.

“…We generated two human induced pluripotency stem cell (hiPSC) lines, RCMGi011-A and 11-B, from skin fibroblast from patient with Mucopolysaccharidosis IV B…”
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Dynamics of Elimination of Plasmids and Expression of VEGF121 Gene Transfected into Human Mesenchymal Stem Cells by Different Methods by Smirnikhina, S. A., Lavrov, A. V., Bochkov, N. P.

“…We compared two methods of transfection (lipofection and electroporation) with plasmid containing VEGF121 gene in four cultures of mesenchymal stem cells from…”
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Creation of Induced Pluripotent Stem Cells RCMGi014-A Using Reprogramming of Urine Cells of a Patient with Fibrodysplasia Ossificans Progressiva Associated with Heterozygous Mutation in the ACVR1 Gene by Kondrateva, E. V., Grigorieva, O. V., Kurshakova, E. V., Panchuk, I. O., Pozhitnova, V. O., Voronina, E. S., Tabakov, V. Yu, Nikishina, I. P., Arsenyeva, S. V., Matkava, V. G., Lavrov, A. V., Smirnikhina, S. A., Kutsev, S. I.

“…Fibrodysplasia ossificans progressiva (FOP) is a severe genetic disease caused by mutations in the ACVR1 gene for which there is currently no effective…”
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Common methods for cytosine methylation analysis in DNA by Smirnikhina, S. A., Lavrov, A. V.

“…The review considers the methods most commonly used to detect DNA methylation, their advantages, potential limitations, and selection for various purposes. A…”
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Cardiomyopathies associated with the DES gene mutations: molecular pathogenesis and gene therapy approaches by Kochergin-Nikitsky, K. S., Zaklyazminskaya, E. V., Lavrov, A. V., Smirnikhina, S. A.

“…Cardiomyopathy (CMP) is a common group of cardiovascular disorders. Genetic (primary) cardiomyopathies are related to abnormalities in more than 100 genes,…”
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Mutagen influence with different mechanisms of action on DNA global methylation in human whole-blood lymphocytes in vitro by Smirnikhina, S A, Voronina, E S, Strelnikov, V V, Tanas, A S, Lavrov, A V

“…Data that support the evidence of mutagens known to cause epigenetic abnormalities that could potentially result in genomic instability and the development of…”
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The Choice of a Donor Molecule in Genome Editing Experiments in Animal Cells by Volodina, O V, Smirnikhina, S A

“…Genome editing is a powerful tool that allows study of the properties of genes or changes to be made to the genetic sequence. Programmable nucleases that can…”
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Mutagen influence with different mechanisms of action on DNA global methylation in human whole-blood lymphocytes in vitro by Smirnikhina, S. A., Voronina, E. S., Strelnikov, V. V., Tanas, A. S., Lavrov, A. V.

“…Data that support the evidence of mutagens known to cause epigenetic abnormalities that could potentially result in genomic instability and the development of…”
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CRISPR-Cas9 Delivery with the Ribonucleoprotein Complexes Increased EGFP Editing Efficiency by Slesarenko, Ya. S., Bykonya, A. G., Anuchina, A. A., Zaynitdinova, M. I., Evtushenko, N. A., Lavrov, A. V., Smirnikhina, S. A.

“…—The rapid development of CRISPR-Cas9 technology has already led to its wide use in many areas of biological research. However, a major roadblock to achieve…”
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Experimental approaches to the target editing of the CFTR gene using CRISPR-Cas9 by Smirnikhina, S.A., Anuchina, A.A., Kochergin-Nikitsky, K.S., Adilgereeva, E.P., Yakushina, V.D., Lavrov, A.V.

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Nuclear heterogeneity and proliferation activity of human adipose derived MSC-like cells by Lavrov, A. V., Smirnikhina, S. A.

“…Adipose tissue (AT) is an easily available source of mesenchymal-like stem cells (MSCs) that are appropriate for applications in regenerative medicine. There…”
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Methods for detection of methylated cytosine residues in DNA by Smirnikhina, S A, Lavrov, A V

“…The article provides analysis of common methods for DNA methylation detection. Advantages and limitations of methods used for different purposes are compared…”
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VEGF gene expression in transfected human multipotent stromal cells by Smirnikhina, S A, Lavrov, A V, Bochkov, N P

“…Dynamics of VEGF gene expression in transfected multipotent stromal cells from adipose tissue was examined using electroporation and lipofection. Differences…”
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