Search Results - "Smillie, J"

Calcitonin gene-related peptide: physiology and pathophysiology by Russell, F A, King, R, Smillie, S-J, Kodji, X, Brain, S D

“…Calcitonin gene-related peptide (CGRP) is a 37-amino acid neuropeptide. Discovered 30 years ago, it is produced as a consequence of alternative RNA processing…”
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The Phospho-Dependent Dynamin-Syndapin Interaction Triggers Activity-Dependent Bulk Endocytosis of Synaptic Vesicles by Clayton, Emma L, Anggono, Victor, Smillie, Karen J, Chau, Ngoc, Robinson, Phillip J, Cousin, Michael A

“…Synaptic vesicles (SVs) are retrieved by more than one mode in central nerve terminals. During mild stimulation, the dominant SV retrieval pathway is classical…”
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VAMP4 Is an Essential Cargo Molecule for Activity-Dependent Bulk Endocytosis by Nicholson-Fish, Jessica C., Kokotos, Alexandros C., Gillingwater, Thomas H., Smillie, Karen J., Cousin, Michael A.

“…The accurate formation of synaptic vesicles (SVs) and incorporation of their protein cargo during endocytosis is critical for the maintenance of…”
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Phosphatidylinositol 4-kinase IIα is a glycogen synthase kinase 3-regulated interaction hub for activity-dependent bulk endocytosis by Blumrich, Eva-Maria, Nicholson-Fish, Jessica C., Pronot, Marie, Davenport, Elizabeth C., Kurian, Dominic, Cole, Adam, Smillie, Karen J., Cousin, Michael A.

“…Phosphatidylinositol 4-kinase IIα (PI4KIIα) generates essential phospholipids and is a cargo for endosomal adaptor proteins. Activity-dependent bulk…”
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Dynamin I phosphorylation by GSK3 controls activity-dependent bulk endocytosis of synaptic vesicles by Clayton, Emma L, Sue, Nancy, O'Leary, Timothy, Wyllie, David J, Robinson, Phillip J, Cheung, Giselle, Sutherland, Calum, Cole, Adam R, Bache, Nicolai, Cousin, Michael A, Smillie, Karen J

“…After neurotransmitter release evoked by intense stimulation, synaptic vesicles are retrieved either by clathrin-mediated endocytosis or by activity-dependent…”
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A Comprehensive Approach to Identifying and Authenticating Botanical Products by Smillie, T J, Khan, I A

“…Whether they are being taken as dietary supplements by the general public or being evaluated in a clinical study, the authenticity of botanical products is a…”
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A Fine Balance of Synaptophysin Levels Underlies Efficient Retrieval of Synaptobrevin II to Synaptic Vesicles by Gordon, Sarah L, Harper, Callista B, Smillie, Karen J, Cousin, Michael A

“…Synaptobrevin II (sybII) is a vesicular soluble NSF attachment protein receptor (SNARE) protein that is essential for neurotransmitter release, and thus its…”
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Simultaneous determination of sesquiterpenes and pyrrolizidine alkaloids from the rhizomes of Petasites hybridus (L.) G.M. et Sch. and dietary supplements using UPLC-UV and HPLC-TOF-MS methods by Avula, Bharathi, Wang, Yan-Hong, Wang, Mei, Smillie, Troy J., Khan, Ikhlas A.

“…UPLC-UV and HPLC-TOF-MS methods have been developed for the analysis of major sesquiterpenes and pyrrolizidine alkaloids from rhizomes of Petasites hybridus…”
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Syndapin I is the phosphorylation-regulated dynamin I partner in synaptic vesicle endocytosis by Robinson, Phillip J, Anggono, Victor, Smillie, Karen J, Graham, Mark E, Valova, Valentina A, Cousin, Michael A

“…Dynamin I is dephosphorylated at Ser-774 and Ser-778 during synaptic vesicle endocytosis (SVE) in nerve terminals. Phosphorylation was proposed to regulate the…”
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Loss of huntingtin function slows synaptic vesicle endocytosis in striatal neurons from the httQ140/Q140 mouse model of Huntington's disease by McAdam, Robyn L., Morton, Andrew, Gordon, Sarah L., Alterman, Julia F., Khvorova, Anastasia, Cousin, Michael A., Smillie, Karen J.

“…Huntington's disease (HD) is caused by CAG repeat expansion within the HTT gene, with the dysfunction and eventual loss of striatal medium spiny neurons a…”
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Quantitative determination of phenolic compounds by UHPLC-UV–MS and use of partial least-square discriminant analysis to differentiate chemo-types of Chamomile/Chrysanthemum flower heads by Avula, Bharathi, Wang, Yan-Hong, Wang, Mei, Avonto, Cristina, Zhao, Jianping, Smillie, Troy J., Rua, Diego, Khan, Ikhlas A.

“…Chamomile/Chrysanthemum authenticated and commercial samples: scatterplot of first and second principal component obtained by PLS-DA on the basis of…”
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Chemical fingerprint analysis and quantitative determination of steroidal compounds from Dioscorea villosa, Dioscorea species and dietary supplements using UHPLC-ELSD by Avula, Bharathi, Wang, Yan-Hong, Ali, Zulfiqar, Smillie, Troy J., Khan, Ikhlas A.

“…ABSTRACT Ultra high‐performance liquid chromatography (UHPLC) with evaporative light scattering detection was used for the quantification of steroidal saponins…”
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A molecular toggle after exocytosis sequesters the presynaptic syntaxin1a molecules involved in prior vesicle fusion by Kavanagh, Deirdre M., Smyth, Annya M., Martin, Kirsty J., Dun, Alison, Brown, Euan R., Gordon, Sarah, Smillie, Karen J., Chamberlain, Luke H., Wilson, Rhodri S., Yang, Lei, Lu, Weiping, Cousin, Michael A., Rickman, Colin, Duncan, Rory R.

“…Neuronal synapses are among the most scrutinized of cellular systems, serving as a model for all membrane trafficking studies. Despite this, synaptic biology…”
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Synaptic Vesicle Recycling Is Unaffected in the Ts65Dn Mouse Model of Down Syndrome by Marland, Jamie R K, Smillie, Karen J, Cousin, Michael A

“…Down syndrome (DS) is the most common genetic cause of intellectual disability, and arises from trisomy of human chromosome 21. Accumulating evidence from…”
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Phosphorylation of syndapin I F-BAR domain at two helix-capping motifs regulates membrane tubulation by Quan, Annie, Xue, Jing, Wielens, Jerome, Smillie, Karen J., Anggono, Victor, Parker, Michael W., Cousin, Michael A., Graham, Mark E., Robinson, Phillip J.

“…Syndapin I (PACSIN 1) is a synaptically enriched membrane tubulating protein that plays important roles in activity-dependent bulk endocytosis and neuronal…”
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Spin correlations in decay chains involving W bosons by Smillie, J.M.

“…We study the extent to which spin assignments of new particles produced at the LHC can be deduced in the decay of a scalar or fermion C into a new stable (or…”
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Measurement of CP violation in stop cascade decays at the LHC by Ellis, J., Moortgat, F., Moortgat-Pick, G., Smillie, J. M., Tattersall, J.

“…We study the potential observation at the LHC of CP-violating effects in stop production and subsequent cascade decays, , , , within the Minimal Supersymmetric…”
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Does pellet size affect the ability of beef heifers to consume a pelleted supplement in a simulated grazing model? by Kelln, L., Newkirk, R.W., Smillie, J., Lardner, H.A., Penner, G.B.

“…The objective was to evaluate pellet consumption and refusals as affected by pellet size. Six ruminally cannulated heifers were used in a replicated 3 × 3…”
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Identification of intermetallic phases in a eutectic Al–Si casting alloy using electron backscatter diffraction pattern analysis by Kral, M.V., McIntyre, H.R., Smillie, M.J.

“…Intermetallic phases in sand cast eutectic Al–Si alloys were characterized using a combination of SEM, EDS and EBSD pattern analysis. Chinese script α-phase…”
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From the LHC to future colliders by De Roeck, A, Ellis, J, Grojean, C, Heinemeyer, S, Jakobs, K, Weiglein, G, Wells, J, Azuelos, G, Dawson, S, Gripaios, B, Han, T, Hewett, J, Lancaster, M, Mariotti, C, Moortgat, F, Moortgat-Pick, G, Polesello, G, Riemann, S, Schumacher, M, Assamagan, K, Bechtle, P, Carena, M, Chachamis, G, Chen, K F, De Curtis, S, Desch, K, Dittmar, M, Dreiner, H, Dührssen, M, Foster, B, Frandsen, M T, Giammanco, A, Godbole, R, Gopalakrishna, S, Govoni, P, Gunion, J, Hollik, W, Hou, W S, Isidori, G, Juste, A, Kalinowski, J, Korytov, A, Kou, E, Kraml, S, Krawczyk, M, Martin, A, Milstead, D, Morton-Thurtle, V, Moenig, K, Mele, B, Ozcan, E, Pieri, M, Plehn, T, Reina, L, Richter-Was, E, Rizzo, T, Rolbiecki, K, Sannino, F, Schram, M, Smillie, J, Sultansoy, S, Tattersall, J, Uwer, P, Webber, B, Wienemann, P

“…Discoveries at the LHC will soon set the physics agenda for future colliders. This report of a CERN Theory Institute includes the summaries of Working Groups…”
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