Search Results - "Smidt, Kamille"

SLC30A3 responds to glucose- and zinc variations in beta-cells and is critical for insulin production and in vivo glucose-metabolism during beta-cell stress by Smidt, Kamille, Jessen, Niels, Petersen, Andreas Brønden, Larsen, Agnete, Magnusson, Nils, Jeppesen, Johanne Bruun, Stoltenberg, Meredin, Culvenor, Janetta G, Tsatsanis, Andrew, Brock, Birgitte, Schmitz, Ole, Wogensen, Lise, Bush, Ashley I, Rungby, Jørgen

“…Ion transporters of the Slc30A- (ZnT-) family regulate zinc fluxes into sub-cellular compartments. beta-cells depend on zinc for both insulin crystallization…”
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Influence of GLP-1 on myocardial glucose metabolism in healthy men during normo- or hypoglycemia by Gejl, Michael, Lerche, Susanne, Mengel, Annette, Møller, Niels, Bibby, Bo Martin, Smidt, Kamille, Brock, Birgitte, Søndergaard, Hanne, Bøtker, Hans Erik, Gjedde, Albert, Holst, Jens Juul, Hansen, Søren Baarsgaard, Rungby, Jørgen

“…Glucagon-like peptide-1 (GLP-1) may provide beneficial cardiovascular effects, possibly due to enhanced myocardial energetic efficiency by increasing…”
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Zinc transporter gene expression is regulated by pro-inflammatory cytokines: a potential role for zinc transporters in beta-cell apoptosis? by Egefjord, Laerke, Jensen, Jens Ledet, Bang-Berthelsen, Claus Heiner, Petersen, Andreas Brønden, Smidt, Kamille, Schmitz, Ole, Karlsen, Allan Ertman, Pociot, Flemming, Chimienti, Fabrice, Rungby, Jørgen, Magnusson, Nils E

“…Beta-cells are extremely rich in zinc and zinc homeostasis is regulated by zinc transporter proteins. beta-cells are sensitive to cytokines, interleukin-1beta…”
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Tomosyn Is Expressed in β-Cells and Negatively Regulates Insulin Exocytosis by WEI ZHANG, LILJA, Lena, MANDIC, Slavena A, GROMADA, Jesper, SMIDT, Kamille, JANSON, Juliette, TAKAI, Yoshimi, BARK, Christina, BERGGREN, Per-Olof, MEISTER, Björn

“…Tomosyn Is Expressed in β-Cells and Negatively Regulates Insulin Exocytosis Wei Zhang 1 , Lena Lilja 2 , Slavena A. Mandic 2 , Jesper Gromada 3 4 , Kamille…”
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Neuronal Calcium Sensor-1 Potentiates Glucose-Dependent Exocytosis in Pancreatic β Cells through Activation of Phosphatidylinositol 4-Kinase β by Gromada, Jesper, Bark, Christina, Smidt, Kamille, Efanov, Alexander M., Janson, Juliette, Mandic, Slavena A., Webb, Dominic-Luc, Zhang, Wei, Meister, Björn, Jeromin, Andreas, Berggren, Per-Olof, Luft, Rolf

“…Cytosolic free Ca2+plays an important role in the molecular mechanisms leading to regulated insulin secretion by the pancreatic β cell. A number of…”
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SLC30A3 Responds to Glucose- and Zinc Variations in ß-Cells and Is Critical for Insulin Production and In Vivo Glucose-Metabolism During ß-Cell Stress by Smidt, Kamille, Jessen, Niels, Petersen, Andreas Brønden, Larsen, Agnete, Magnusson, Nils, Jeppesen, Johanne Bruun, Stoltenberg, Meredin, Culvenor, Janetta G, Tsatsanis, Andrew, Brock, Birgitte, Schmitz, Ole, Wogensen, Lise, Bush, Ashley I, Rungby, Jørgen

“…Background Ion transporters of the Slc30A- (ZnT-) family regulate zinc fluxes into sub-cellular compartments. [beta]-cells depend on zinc for both insulin…”
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A nine-nucleotide deletion and splice variation in the coding region of the interferon induced ISG12 gene by Smidt, Kamille C.J., Hansen, Lise Lotte, Søgaard, T.Max.M., Petersen, Lone K., Knudsen, Ulla B., Martensen, Pia M.

“…Interferons (IFNs) are a family of cytokines with growth inhibitory, and antiviral functions. IFNs exert their biological actions through the expression of…”
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ZnT3: a zinc transporter active in several organs by Smidt, Kamille, Rungby, Jørgen

“…The review collects the emerging information about zinc transporter 3 (ZnT3). ZnT3 has been associated with Alzheimer’s disease, airway diseases and diabetes…”
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The zinc transporter Zip14 (SLC39a14) affects Beta-cell Function: Proteomics, Gene expression, and Insulin secretion studies in INS-1E cells by Maxel, Trine, Smidt, Kamille, Petersen, Charlotte C., Honoré, Bent, Christensen, Anne K., Jeppesen, Per B., Brock, Birgitte, Rungby, Jørgen, Palmfeldt, Johan, Larsen, Agnete

“…Insulin secretion from pancreatic beta-cells is dependent on zinc ions as essential components of insulin crystals, zinc transporters are thus involved in the…”
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Expression Patterns and Correlations with Metabolic Markers of Zinc Transporters ZIP14 and ZNT1 in Obesity and Polycystic Ovary Syndrome by Maxel, Trine, Svendsen, Pernille Fog, Smidt, Kamille, Lauridsen, Jesper Krogh, Brock, Birgitte, Pedersen, Steen Bønlykke, Rungby, Jørgen, Larsen, Agnete

“…Polycystic ovary syndrome (PCOS) is associated with infertility, increased androgen levels, and insulin resistance. In adipose tissue, zinc facilitates insulin…”
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Effects of zinc supplementation and zinc chelation on in vitro β-cell function in INS-1E cells by Nygaard, Sanne Bjørn, Larsen, Agnete, Knuhtsen, Astrid, Rungby, Jørgen, Smidt, Kamille

“…Zinc is essential for the activities of pancreatic β-cells, especially insulin storage and secretion. Insulin secretion leads to co-release of zinc which…”
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Uptake of silver from metallic silver surfaces induces cell death and a pro-inflammatory response in cultured J774 macrophages by Locht, Linda J, Smidt, Kamille, Rungby, Jørgen, Stoltenberg, Meredin, Larsen, Agnete

“…In clinical medicine metallic silver is used as anti-bacterial coating on various catheters, bandages and prostheses. By means of dissolucytosis, i.e…”
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Zinc-transporter genes in human visceral and subcutaneous adipocytes: Lean versus obese by Smidt, Kamille, Pedersen, Steen B., Brock, Birgitte, Schmitz, Ole, Fisker, Sanne, Bendix, Jørgen, Wogensen, Lise, Rungby, Jørgen

“…Zinc ions influence adipose tissue metabolism by regulating leptin secretion and by promoting free fatty acid release and glucose uptake. The mechanisms…”
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The zinc transporter ZNT3 co-localizes with insulin in INS-1E pancreatic beta cells and influences cell survival, insulin secretion capacity, and ZNT8 expression by Smidt, Kamille, Larsen, Agnete, Brønden, Andreas, Sørensen, Karen S., Nielsen, Julie V., Praetorius, Jeppe, Martensen, Pia M., Rungby, Jørgen

“…Zinc trafficking in pancreatic beta cells is tightly regulated by zinc transporting (ZNTs) proteins. The role of different ZNTs in the beta cells is currently…”
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Exogenous Metallothionein Potentiates the Insulin Response at Normal Glucose Concentrations in INS‐1E Beta‐Cells without Disturbing Intracellular ZnT8 Expression by Nygaard, Sanne B., Lund, Ninna S., Larsen, Agnete, Pedersen, Nanna, Rungby, Jørgen, Smidt, Kamille

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Targeting amyloid-beta by glucagon-like peptide -1 (GLP-1) in Alzheimer's disease and diabetes by Bak, Ann Mosegaard, Egefjord, Lærke, Gejl, Michael, Steffensen, Charlotte, Stecher, Chalotte Willemann, Smidt, Kamille, Brock, Birgitte, Rungby, Jørgen

“…Epidemiological evidence suggests an association between type 2 diabetes (T2DM) and Alzheimer's disease (AD), in that one disease increases the risk of the…”
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siRNA-mediated knock-down of ZnT3 and ZnT8 affects production and secretion of insulin and apoptosis in INS-1E cells by PETERSEN, ANDREAS B, SMIDT, KAMILLE, MAGNUSSON, NILS E, MOORE, FABRICE, EGEFJORD, LÆRKE, RUNGBY, JØRGEN

“…Petersen AB, Smidt K, Magnusson NE, Moore F, Egefjord L, Rungby J. siRNA-mediated knock-down of ZnT3 and ZnT8 affects production and secretion of insulin and…”
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Gene expression of the zinc transporter ZIP14 (SLC39a14) is affected by weight loss and metabolic status and associates with PPARγ in human adipose tissue and 3T3-L1 pre-adipocytes by Maxel, Trine, Smidt, Kamille, Larsen, Agnete, Bennetzen, Marianne, Cullberg, Karina, Fjeldborg, Karen, Lund, Sten, Pedersen, Steen B, Rungby, Jørgen

“…The expansion and function of adipose tissue are important during the development of insulin resistance and inflammation in obesity. Zinc dyshomeostasis is…”
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Effects of zinc supplementation and zinc chelation on in vitro [beta]-cell function in INS-1E cells by Nygaard, Sanne Bjarn, Larsen, Agnete, Knuhtsen, Astrid, Rungby, Jargen, Smidt, Kamille

“…Zinc is essential for the activities of pancreatic [beta]-cells, especially insulin storage and secretion. Insulin secretion leads to co-release of zinc which…”
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Measurement of free GH and bioactive IGF-I in non-diabetic haemodialysis patients treated with GH for 7 days by FRYSTYK, Jan, BORN DJURHUUS, Christian, JOHANSEN, Thue, LANGE, Martin, SMIDT, Kamille, SANDAHL CHRISTIANSEN, Jens

“…End-stage renal failure (ESRF) patients demonstrate augmented growth hormone (GH) secretion, but normal insulin-like growth factor-I (IGF-I) concentrations,…”
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