Search Results - "Smets, Dries"
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Protein Transport Across the Bacterial Plasma Membrane by the Sec Pathway
Published in The Protein Journal (15-06-2019)“…More than a third of all bacterial polypeptides, comprising the ‘exportome’, are transported to extracytoplasmic locations. Most of the exportome is targeted…”
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Journal Article -
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Signal Peptide-rheostat Dynamics Delay Secretory Preprotein Folding
Published in Journal of molecular biology (15-10-2022)“…[Display omitted] •Higher hydrophobicity drives partial helical structure formation in signal peptides.•Partially helical structured signal peptide elevate…”
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Journal Article -
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Evolutionary adaptation of the protein folding pathway for secretability
Published in The EMBO journal (01-12-2022)“…Secretory preproteins of the Sec pathway are targeted post‐translationally and cross cellular membranes through translocases. During cytoplasmic transit,…”
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Journal Article -
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Inner Membrane Translocases and Insertases
Published in Sub-cellular biochemistry (2019)“…The inner membrane of Gram-negative bacteria is a ~6 nm thick phospholipid bilayer. It forms a semi-permeable barrier between the cytoplasm and periplasm…”
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Journal Article