Search Results - "Smetana, Juliana H.C."

C7orf59/LAMTOR4 phosphorylation and structural flexibility modulate Ragulator assembly by Rasheed, Nadia, Lima, Tatiani B., Mercaldi, Gustavo F., Nascimento, Andrey F.Z., Silva, Ana L.S., Righetto, Germanna L., Bar‐Peled, Liron, Shen, Kuang, Sabatini, David M., Gozzo, Fabio C., Aparicio, Ricardo, Smetana, Juliana H.C.

“…Ragulator is a pentamer composed of p18, MP1, p14, C7orf59, and hepatitis B virus X‐interacting protein (HBXIP; LAMTOR 1—5) which acts as a lysosomal scaffold…”
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Interaction analysis of the heterotrimer formed by the phosphatase 2A catalytic subunit, α4 and the mammalian ortholog of yeast Tip41 (TIPRL) by Smetana, Juliana H.C, Zanchin, Nilson I.T

“…Type 2A serine/threonine phosphatases are part of the PPP subfamily that is formed by PP2A, PP4 and PP6, and participate in a variety of cellular processes…”
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Type I interferons are essential while type II interferon is dispensable for protection against St. Louis encephalitis virus infection in the mouse brain by Rocha, Rebeca Froes, Del Sarto, Juliana L., Gomes, Giovanni F., Gonçalves, Mariana P., Rachid, Milene A., Smetana, Juliana H. C., Souza, Daniele G., Teixeira, Mauro Martins, Marques, Rafael Elias

“…St. Louis encephalitis virus (SLEV) is a neglected mosquito-borne flavivirus that causes severe neurological disease in humans. SLEV replication in the central…”
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Crystal structure of the human Tip41 orthologue, TIPRL, reveals a novel fold and a binding site for the PP2Ac C-terminus by Scorsato, Valéria, Lima, Tatiani B., Righetto, Germanna L., Zanchin, Nilson I. T., Brandão-Neto, José, Sandy, James, Pereira, Humberto D’Muniz, Ferrari, Állan J. R., Gozzo, Fabio C., Smetana, Juliana H. C., Aparicio, Ricardo

“…TOR signaling pathway regulator-like (TIPRL) is a regulatory protein which inhibits the catalytic subunits of Type 2A phosphatases. Several cellular contexts…”
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Identification and Characterization of an Alternatively Spliced Isoform of the Human Protein Phosphatase 2Aα Catalytic Subunit by Migueleti, Deivid L.S., Smetana, Juliana H.C., Nunes, Hugo F., Kobarg, Jörg, Zanchin, Nilson I.T.

“…PP2A is the main serine/threonine-specific phosphatase in animal cells. The active phosphatase has been described as a holoenzyme consisting of a catalytic, a…”
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