Search Results - "Smesny, S"
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Omega-6 to omega-3 polyunsaturated fatty acid ratio and subsequent mood disorders in young people with at-risk mental states: a 7-year longitudinal study
Published in Translational psychiatry (29-08-2017)“…While cross-sectional studies suggest that patients with mood disorders have a higher ratio of omega-6 to omega-3 polyunsaturated fatty acids (PUFAs) and lower…”
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Prediction of transition from ultra-high risk to first-episode psychosis using a probabilistic model combining history, clinical assessment and fatty-acid biomarkers
Published in Translational psychiatry (20-09-2016)“…Current criteria identifying patients with ultra-high risk of psychosis (UHR) have low specificity, and less than one-third of UHR cases experience transition…”
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The Ultra-High-Risk for psychosis groups: Evidence to maintain the status quo
Published in Schizophrenia research (01-05-2018)“…Individuals are considered Ultra-High-Risk (UHR) for psychosis if they meet a set of standardised criteria including presumed genetic vulnerability (Trait), or…”
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Erythrocyte glutathione levels as long-term predictor of transition to psychosis
Published in Translational psychiatry (21-03-2017)“…A high proportion of individuals deemed at elevated risk for psychosis will actually never progress to develop the illness. Pharmaceutical intervention may not…”
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Dynamic prediction of transition to psychosis using joint modelling
Published in Schizophrenia research (01-12-2018)“…Considerable research has been conducted seeking risk factors and constructing prediction models for transition to psychosis in individuals at ultra-high risk…”
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Disturbed glutathione antioxidative defense is associated with structural brain changes in neuroleptic-naïve first-episode psychosis patients
Published in Prostaglandins, leukotrienes and essential fatty acids (01-09-2018)“…Oxidative stress and impaired antioxidant defense are reported in schizophrenia and are thought to be associated with disturbed neurodevelopment, brain…”
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Omega-3 fatty acid supplementation changes intracellular phospholipase A2 activity and membrane fatty acid profiles in individuals at ultra-high risk for psychosis
Published in Molecular psychiatry (01-03-2014)“…The identification of an ultra-high risk (UHR) profile for psychosis and a greater understanding of its prodrome have led to increasing interest in early…”
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Basic symptoms in young people at ultra-high risk of psychosis: Association with clinical characteristics and outcomes
Published in Schizophrenia research (01-02-2020)“…There has been limited research into the predictive value of basic symptoms and their relationship with other psychopathology in patients identified using the…”
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Classification of first-episode psychosis using cortical thickness: A large multicenter MRI study
Published in European neuropsychopharmacology (01-06-2021)“…Machine learning classifications of first-episode psychosis (FEP) using neuroimaging have predominantly analyzed brain volumes. Some studies examined cortical…”
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ZNF804A genetic variation (rs1344706) affects brain grey but not white matter in schizophrenia and healthy subjects
Published in Psychological medicine (01-01-2015)“…Genetic variation in the gene encoding ZNF804A, a risk gene for schizophrenia, has been shown to affect brain functional endophenotypes of the disorder, while…”
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Prostaglandin-mediated signaling in schizophrenia
Published in International review of neurobiology (2004)Get more information
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Impaired niacin sensitivity in acute first-episode but not in multi-episode schizophrenia
Published in Prostaglandins, leukotrienes and essential fatty acids (01-06-2005)“…Niacin (vitamin B3) flushing—a marker of altered prostaglandin signaling—is indirectly linked to the phospholipid–prostaglandin metabolism. Diminished skin…”
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P02-342 - Functional MRI in twins discordant for schizophrenia during a working memory task: Preliminary results from the eutwinss study
Published in European psychiatry (2011)“…Introduction Working memory deficits are considered a core feature of disturbed cognition in schizophrenia. Recent neuropsychological studies in twins suggest…”
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NEURAPRO: a multi-centre RCT of omega-3 polyunsaturated fatty acids versus placebo in young people at ultra-high risk of psychotic disorders—medium-term follow-up and clinical course
Published in NPJ schizophrenia (25-06-2018)“…This study reports a medium-term follow-up of a randomised, double-blind, placebo-controlled trial of omega-3 polyunsaturated fatty acids (PUFA) in ultra-high…”
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Aging Effects on Regional Brain Structural Changes in Schizophrenia
Published in Schizophrenia bulletin (01-06-2012)“…Although mostly conceptualized as a neurodevelopmental disorder, there is an increasing interest in progressive changes of cognitive deficits and brain…”
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Increased calcium-independent phospholipase A2 activity in first but not in multiepisode chronic schizophrenia
Published in Biological psychiatry (1969) (15-02-2005)“…Increased activity of calcium independent phospholipase A2 (iPLA2) has repeatedly been found in the serum of unmedicated first-episode schizophrenia patients…”
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Omega-3 fatty acid supplementation changes intracellular phospholipase A sub(2) activity and membrane fatty acid profiles in individuals at ultra-high risk for psychosis
Published in Molecular psychiatry (01-03-2014)“…The identification of an ultra-high risk (UHR) profile for psychosis and a greater understanding of its prodrome have led to increasing interest in early…”
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Omega-3 fatty acid supplementation changes intracellular phospholipase [A.sub.2] activity and membrane fatty acid profiles in individuals at ultra-high risk for psychosis
Published in Molecular psychiatry (01-03-2014)“…The identification of an ultra-high risk (UHR) profile for psychosis and a greater understanding of its prodrome have led to increasing interest in early…”
Get full text
Journal Article