Search Results - "Smerhovsky, Z"

DNA repair genetic polymorphisms and risk of colorectal cancer in the Czech Republic by Pardini, B, Naccarati, A, Novotny, J, Smerhovsky, Z, Vodickova, L, Polakova, V, Hanova, M, Slyskova, J, Tulupova, E, Kumar, R, Bortlik, M, Barale, R, Hemminki, K, Vodicka, P

“…Colorectal cancer represents a complex disease where susceptibility may be influenced by genetic polymorphisms in the DNA repair system. In the present study…”
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Genotype and haplotype analysis of TP53 gene and the risk of pancreatic cancer: an association study in the Czech Republic by Naccarati, A., Pardini, B., Polakova, V., Smerhovsky, Z., Vodickova, L., Soucek, P., Vrana, D., Holcatova, I., Ryska, M., Vodicka, P.

“…Pancreatic carcinoma is the fourth leading cause of cancer-related deaths in the Czech Republic, with only a minimum of patients surviving 5 years. The…”
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Cyclin D1 splice site variant triggers chromosomal aberrations in healthy humans by Hemminki, K, Musak, L, Vymetalkova, V, Smerhovsky, Z, Halasova, E, Osina, O, Letkova, L, Försti, A, Vodickova, L, Buchancova, J, Vodicka, P

“…151 0.01# 1.85# 1.17# 2.93# 151 0.003# 1.99# 1.26# 3.13# 151 0.21 1.33 0.86 2.06…”
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Genotype and haplotype analysis of cell cycle genes in sporadic colorectal cancer in the Czech Republic by Polakova, V, Pardini, B, Naccarati, A, Landi, S, Slyskova, J, Novotny, J, Vodickova, L, Bermejo, J.L, Hanova, M, Smerhovsky, Z, Tulupova, E, Kumar, R, Hemminki, K, Vodicka, P

“…The Czech Republic has one of the highest incidences of colorectal cancer (CRC) in the world. To assess the role of genetic variants on the disease, we…”
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Risk of Cancer in an Occupationally Exposed Cohort with Increased Level of Chromosomal Aberrations by Smerhovsky, Zdenek, Landa, Karel, Rössner, Pavel, Brabec, Marek, Zudova, Zdena, Hola, Nora, Pokorna, Zdena, Mareckova, Julie, Hurychova, Dana

“…We used cytogenetic analysis to carry out a cohort study in which the major objective was to test the association between frequency of chromosomal aberrations…”
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Occupational Exposure to Carcinogens in Estonia, Latvia, Lithuania and the Czech Republic in 1997 by Kauppinen, Timo, Pajarskiene, Birute, Podniece, Zinta, Rjazanov, Vladislav, Smerhovsky, Zdenek, Veidebaum, Toomas, Leino, Timo

“…Objectives The aim of the study was to estimate the numbers of workers exposed to carcinogens in Estonia, Latvia, Lithuania, and the Czech Republic. Methods…”
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Neurological and neurophysiological examinations on workers with chronic poisoning by 2,3,7,8-TCDD: follow-up 35 years after exposure by Urban, P., Pelclová, D., Lukáš, E., Kupka, K., Preiss, J., Fenclová, Z., Šmerhovský, Z.

“…Between 1965 and 1968, about 350 workers were accidentally exposed to 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin (TCDD) in a chemical plant, which was producing…”
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Biological Monitoring of Child Lead Exposure in the Czech Republic by Cikrt, Miroslav, Smerhovsky, Zdenek, Blaha, Karel, Nerudova, Jana, Sediva, Viera, Fornuskova, Helena, Knotkova, Jana, Roth, Zdenek, Kodl, Miloslav, Fitzgerald, Edward

“…The area around the Pribram lead smelter has been recognized to be heavily contaminated by lead (Pb). In the early 1970s, several episodes of livestock lead…”
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Renal and Neurologic Effects of Cadmium, Lead, Mercury, and Arsenic in Children: Evidence of Early Effects and Multiple Interactions at Environmental Exposure Levels by de Burbure, Claire, Buchet, Jean-Pierre, Leroyer, Ariane, Nisse, Catherine, Haguenoer, Jean-Marie, Mutti, Antonio, Smerhovský, Zdenek, Cikrt, Miroslav, Trzcinka-Ochocka, Malgorzata, Razniewska, Grazyna, Jakubowski, Marek, Bernard, Alfred

“…Lead, cadmium, mercury, and arsenic are common environmental pollutants in industrialized countries, but their combined impact on children's health is little…”
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Chromosomal Damage among Medical Staff Occupationally Exposed to Volatile Anesthetics, Antineoplastic Drugs, and Formaldehyde by Musak, Ludovit, Smerhovsky, Zdenek, Halasova, Erika, Osina, Oto, Letkova, Lucia, Vodickova, Ludmila, Polakova, Veronika, Buchancova, Janka, Hemminki, Kari, Vodicka, Pavel

“…Objectives Structural chromosomal aberrations in blood lymphocytes represent a biomarker for cellular damage caused by genotoxic carcinogens and are an…”
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Chromosomal Aberrations in Lymphocytes of Healthy Subjects and Risk of Cancer by Rossner, Pavel, Boffetta, Paolo, Ceppi, Marcello, Bonassi, Stefano, Smerhovsky, Zdenek, Landa, Karel, Juzova, Dagmar, Šrám, Radim J.

“…There is evidence that increased frequency of chromosomal aberration (CA) in peripheral blood lymphocytes is a predictor of cancer, but further data are needed…”
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Chromosomal damage in peripheral blood lymphocytes of newly diagnosed cancer patients and healthy controls by Vodicka, Pavel, Polivkova, Zdenka, Sytarova, Sylvie, Demova, Hana, Kucerova, Marie, Vodickova, Ludmila, Polakova, Veronika, Naccarati, Alessio, Smerhovsky, Zdenek, Ambrus, Miloslav, Cerna, Marie, Hemminki, Kari

“…Background: The majority of human cancers arise from cells unable to maintain genomic stability. Recent prospective studies indicated that enhanced chromosomal…”
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Differences in nucleotide excision repair capacity between newly diagnosed colorectal cancer patients and healthy controls by Slyskova, Jana, Naccarati, Alessio, Pardini, Barbara, Polakova, Veronika, Vodickova, Ludmila, Smerhovsky, Zdenek, Levy, Miroslav, Lipska, Ludmila, Liska, Vaclav, Vodicka, Pavel

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Chromosomal aberrations in tire plant workers and interaction with polymorphisms of biotransformation and DNA repair genes by Musak, Ludovit, Soucek, Pavel, Vodickova, Ludmila, Naccarati, Alessio, Halasova, Erika, Polakova, Veronika, Slyskova, Jana, Susova, Simona, Buchancova, Janka, Smerhovsky, Zdenek, Sedikova, Jana, Klimentova, Gabriela, Osina, Oto, Hemminki, Kari, Vodicka, Pavel

“…We evaluated chromosomal aberrations in lymphocytes of 177 workers exposed to xenobiotics in a tire plant and in 172 controls, in relation to their genetic…”
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DNA damage, DNA repair rates and mRNA expression levels of cell cycle genes (TP53, p21CDKN1A, BCL2 and BAX) with respect to occupational exposure to styrene by HANOVA, Monika, VODICKOVA, Ludmila, KUMAR, Rajiv, HEMMINKI, Kari, VODICKA, Pavel, VACLAVIKOVA, Radka, SMERHOVSKY, Zdenek, STETINA, Rudolf, HLAVAC, Pavel, NACCARATI, Alessio, SLYSKOVA, Jana, POLAKOVA, Veronika, SOUCEK, Pavel

“…We studied the relationship between DNA damage, DNA repair rates and messenger RNA (mRNA) expression levels of cell cycle genes TP53, p21CDKN1A, BCL2 and BAX…”
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Cytogenetic analysis and occupational health in the Czech Republic by Sra, R J, Rossner, P, Smerhovsky, Z

“…This paper summarizes the experiences of the Czech Hygiene Service since the middle 1970s until the present time, using cytogenetic analysis as a biomarker of…”
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Cytogenetic analysis using fluorescence in situ hybridization (FISH) to evaluate occupational exposure to carcinogens by Sram, Radim J., Beskid, Olena, Binkova, Blanka, Rossner, Pavel, Smerhovsky, Zdenek

“…Chromosomal aberrations determined by conventional method or fluorescence in situ hybridization (FISH) technique with whole chromosome painting are used as…”
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Neurological and neurophysiological examinations on workers with chronic poisoning by 2,3,7,8-TCDD: follow-up 35years after exposure by Urban, P, Pelclova, D, Lukas, E, Kupka, K, Preiss, J, Fenclova, Z, Smerhovsky, Z

“…Between 1965 and 1968, about 350 workers were accidentally exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in a chemical plant, which was producing…”
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2,3,7,8-TCDD exposure, endothelial dysfunction and impaired microvascular reactivity by Pelclová, Daniela, Prázny, Martin, Skrha, Jan, Fenclová, Zdenka, Kalousová, Marta, Urban, Pavel, Navrátil, Tomás, Senholdová, Zdenka, Smerhovsky, Zdenek

“…Vascular function was examined in subjects with long-term high level of serum 2,3,7,8-tetrachlorodibenzo- p-dioxin (TCDD) during their follow-up visits. Their…”
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Increased risk of cancer in radon-exposed miners with elevated frequency of chromosomal aberrations by Smerhovsky, Zdenek, Landa, Karel, Rőssner, Pavel, Juzova, Dagmar, Brabec, Marek, Zudova, Zdena, Hola, Nora, Zarska, Hana, Nevsimalova, Emilie

“…In spite of the extensive use of cytogenetic analysis of human peripheral blood lymphocytes in the biomonitoring of exposure to various mutagens and…”
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