Search Results - "Smelt, A.H.M."

Hyperlipoproteinemia affects cytokine production in whole blood samples ex vivo. The influence of lipid-lowering therapy by Mohrschladt, M.F, Weverling-Rijnsburger, A.W.E, de Man, F.H.A.F, Stoeken, D.-J, Sturk, A, Smelt, A.H.M, Westendorp, R.G.J

“…Low-density lipoprotein (LDL)-receptor deficient mice, thus hypercholesterolemic, combine protection against infection with an ex vivo two- to threefold higher…”
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Triglycerides and gallstone formation by Smelt, A.H.M.

“…Changes in bile acid (BA) metabolism and gallbladder function are critical factors in the pathogenesis of gallstones. Patients with hypertriglyceridemia (HTG)…”
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Superior sagittal sinus thrombosis and thyrotoxicosis : possible association in two cases by SIEGERT, C. E. H, SMELT, A. H. M, DE BRUIN, T. W. A

“…Superior sagittal sinus thrombosis is an uncommon cerebrovascular accident that is frequently associated with diseases that may contribute to the development…”
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Cardiovascular disease and mortality in statin-treated patients with familial hypercholesterolemia by Mohrschladt, M.F, Westendorp, R.G.J, Gevers Leuven, J.A, Smelt, A.H.M

“…Patients with familial hypercholesterolemia (FH) are at an increased risk of premature cardiovascular disease (CVD). The benefits of statin therapy are not…”
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Gall bladder dysmotility: a risk factor for gall stone formation in hypertriglyceridaemia and reversal on triglyceride lowering therapy by bezafibrate and fish oil by Jonkers, I J A M, Smelt, A H M, Ledeboer, M, Hollum, M E, Biemond, I, Kuipers, F, Stellaard, F, Boverhof, R, Meinders, A E, Lamers, C H B W, Masclee, A A M

“…Background and aim: The aim of this study was to unravel the mechanisms responsible for the increased risk of gall stone disease in hypertriglyceridaemia (HTG)…”
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Modulating effect of the A-278C promoter polymorphism in the cholesterol 7alpha-hydroxylase gene on serum lipid levels in normolipidaemic and hypertriglyceridaemic individuals by HOFMAN, M. K, GROENENDIJK, M, VERKUIJLEN, Pjjh, JONKERS, Ijam, MOHRSCHLADT, M. F, SMELT, A. H. M, PRINCEN, H. M. G

“…The rate-limiting enzyme in the conversion of cholesterol into bile acids is cholesterol 7alpha-hydroxylase (CYP7A1). An A to C substitution 278 bp upstream in…”
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No effect of simvastatin treatment on C-reactive protein in patients with familial hypercholesterolemia by Mohrschladt, M.F, de Maat, M.P.M, Westendorp, R.G.J, Smelt, A.H.M

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Long term efficacy and safety of atorvastatin in the treatment of severe type III and combined dyslipidaemia by van Dam, M, Zwart, M, de Beer, F, Smelt, A H M, Prins, M H, Trip, M D, Havekes, L M, Lansberg, P J, Kastelein, J J P

“…Background: Fibric acid derivatives and HMG-CoA reductase inhibitors are effective in combination for treating patients with familial dysbetalipoproteinaemia…”
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Alterations in the tissue factor pathway in hypertriglyceridemia do not cause a “pro-coagulant state”; Effects of lipid lowering therapy by bezafibrate by Jonkers, I.J.A.M, de Man, F.H.A.F, van der Laarse, A, Smelt, A.H.M, Bertina, R.M

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Bezafibrate reduces heart rate and blood pressure in patients with hypertriglyceridemia by Jonkers, I.J.A.M., de Man, F.H.A.F., van der Laarse, A., Frölich, M., Smelt, A.H.M.

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Mutations in the low density lipoprotein receptor gene of familial hypercholesterolemic patients detected by denaturing gradient gel electrophoresis and direct sequencing by Lombardi, P. (TNO-PG, Leiden, The Netherlands.), Sijbrands, E.J.G, Giessen, K. van de, Smelt, A.H.M, Kastelein, J.J.P, Frants, R.R, Havekes, L.M

“…Familial hypercholesterolemia (FH) results from mutations in the low density lipoprotein receptor (LDLR) gene. We applied denaturing gradient gel…”
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The influence of mutations in apolipoprotein c3, lipoprotein lipase and hepatic lipase on the expression of type iii hyperlipoproteinemia by de Beer, F., Smelt, A.H.M., Hanifi Moghaddam, P., Sandkuijl, L.A., van Vark, L.C., Kastelein, J.J.P., Jansen, H., Stalenhoef, A.F.H., Havekes, L.M.

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1.P.32 Lipoprotein lipase is needed for the interaction of very low density lipoproteins with heparan sulphate proteoglycans by de Beer, F., de Man, F.H.A.F., Smelt, A.H.M., van der Laarse, A., Havekes, L.M.

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Alcohol consumption and high-density lipoprotein levels in hypercholesterolemic patients by Sijbrands, E.J.G., Westendorp, R.G.J., Gevers Leuven, J.A., Smelt, A.H.M.

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Heterozygosity for ABCA1 gene mutations: effects on enzymes, apolipoproteins and lipoprotein particle size by Kuivenhoven, J.A., Hovingh, G.K., van Tol, A., Jauhiainen, M., Ehnholm, C., Fruchart, J.C., Brinton, E.A., Otvos, J.D., Smelt, A.H.M., Brownlee, A., Zwinderman, A.H., Hayden, M.R., Kastelein, J.J.P.

“…A cohort of 13 female and 14 male heterozygotes for ATP binding cassette A1 ( ABCA1) gene defects was directly compared with 13 and 14 unaffected female and…”
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The relation of lipoprotein(a), apolipoprotein E2, and smoking in combined hyperlipidemia by Bouman, L.V.C., Sijbrands, E.J.G., Vroom, T.F.F.P., Hollaar, L., Gevers Leuven, J.A., van der Laarse, A., Smelt, A.H.M.

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Effects of fish oil on oxidation resistance of very low density lipoprotein in hypertriglyceride by Hau, M.F., Smelt, A.H.M., Bindels, A.J.G.H., Sijbrands, E.J.G., Onkenhout, W., van der Laarse, A., van Duyvenvoorde, W., Princen, H.M.G.

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Th-P15:62 Plasma APOAV levels are markedly elevated in severe hypertriglyceridemia and are positively correlated with the APOA5 S19W polymorphism by Henneman, P., Schaap, F.G., Havekes, L.M., Rensen, P.C.N., Frants, R.R., Van Tol, A., Hattori, H., Smelt, A.H.M.

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2P-0560 TaqIB polymorphism in CETP gene: the influence on incidence of cardiovascular disease in patients with familial hypercholesterolemia by Mohrschladt, M.F., De Beer, F., Hofman, M., Van der Krabben, M., Westendorp, R.G.J., Smelt, A.H.M.

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Increased TNF-α production ex vivo is associated with elevated CRP and fibrinogen levels in hypertriglyceridemia. Reversal upon lipid-lowering therapy by bezafibrate by Jonkers, I.J.A.M., Mohrschladt, M.F.M., de Man, F.H.A.F., van der Laarse, A., Smelt, A.H.M.

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