Search Results - "Smejkal, R"

Dual blockade of P-selectin and β2-integrin in the liver inflammatory response after uncontrolled hemorrhagic shock by ANAYA-PRADO, R, TOLEDO-PEREYRA, L. H, COLLINS, J. T, SMEJKAL, R, MCCLAREN, J, CROUCH, L. D, WARD, P. A

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Routine initial computed tomography of the chest in blunt torso trauma by Smejkal, R, O'Malley, K F, David, E, Cernaianu, A C, Ross, S E

“…Computer tomography (CT) is an effective technique in the initial evaluation of the abdomen and head following blunt trauma. To evaluate the role of CT of the…”
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Distance geometry of alpha-substituted 2,2-diphenylpropionate antimuscarinics by Gordon, R K, Breuer, E, Padilla, F N, Smejkal, R M, Chiang, P K

“…Quantitative structure-activity relationships between pharmacological activities and physical properties of a series of 2,2-diphenylpropionate compounds were…”
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Leishmania braziliensis panamensis: increased infectivity resulting from heat shock by Smejkal, R M, Wolff, R, Olenick, J G

“…Promastigotes of Leishmania braziliensis panamensis were subjected to a heat shock transformation yielding an amastigote-like stage. During the process of…”
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Muscarinic receptor subtype specificity of (N,N-dialkylamino)alkyl 2-cyclohexyl-2-phenylpropionates: cylexphenes (cyclohexyl-substituted aprophen analogs) by Leader, Haim, Gordon, Richard K, Baumgold, Jesse, Boyd, Victoria L, Newman, Amy H, Smejkal, Ruthann M, Chiang, Peter K

“…A series of aprophen [(N,N-diethylamino)ethyl 2,2-diphenylpropionate] analogues, called cylexphenes, were synthesized with alterations in (1) the chain length…”
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Synthesis and antimuscarinic activity of 2-[N-(ethyl)-(N-beta-hydroxyethyl)]aminoethyl 2,2-diphenylpropionate, a metabolite of aprophen by Brown, N D, Leader, H, Phillips, L R, Smejkal, R M, Gordon, R K, Chiang, P K

“…The preparation of 2-[N-(ethyl)-(N-beta-hydroxyethyl)]amino-ethyl 2,2-diphenylpropionate (1), a metabolite of aprophen [2-diethylaminoethyl…”
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Binary antidotes for organophosphate poisoning: aprophen analogs that are both antimuscarinics and carbamates by Leader, Haim, Smejkal, Ruthann M, Payne, Charlotte S, Padilla, Felipe N, Doctor, B. P, Gordon, Richard K, Chiang, Peter K

“…Prophylaxis against organophosphate poisoning can be achieved by pretreatment with physostigmine or pyridostigmine, which are carbamates, and aprophen, which…”
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Use of spiral vein graft to bypass occluded subclavian vein by Jain, K M, Smejkal, R

“…A patient presented with massive swelling of left arm secondary to left radio-cephalic fistula and ipsilateral subclavian vein occlusion. This was successfully…”
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Blood antibodies and uncrossmatched type O blood by Unkle, D, Smejkal, R, Snyder, R, Lessig, M, Ross, S E

“…The immediate transfusion of uncrossmatched type O blood in the initial resuscitation of the trauma victim remains controversial. To examine difficulties in…”
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Myocardial contusion without creatine kinase--MB elevation by Unkle, D W, Smejkal, R, O'Malley, K F

“…Myocardial contusion after chest trauma remains one of the major complexities of trauma care today. Diagnostic methods such as 12-lead electrocardiography and…”
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Effects of ultraviolet light on the in vitro assembly of microtubules by Zaremba, Terrye G, LeBon, Thomas R, Millar, David B, Smejkal, Ruthann M, Hawley, Robert J

“…Exposure of microtubular protein to ultraviolet light inhibits its assembly into morphologically normal microtubules. This effect appeared to result primarily…”
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Design and synthesis of antimuscarinics based on physical and mechanical attributes by Gordon, R K, Smejkal, R M, Breuer, E, Chiang, P K

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Studies on the mechanism of cytotoxicity of 3-deazaguanosine in human cancer cells by PAGE, T, JACOBSEN, S. J, SMEJKAL, R. M, SCHEELE, J, NYHAN, W. L, MANGUM, J. H, ROBINS, R. K

“…The mechanism of toxicity of 3-deazaguanosine was studied in a number of human tumor cell lines by determination of the effects of various purine compounds on…”
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Sialyl Lewis(x) analog improves liver function by decreasing neutrophil migration after hemorrhagic shock by Rubio-Avilla, J, Palma-Vargas, J M, Collins, J T, Smejkal, R, McLaren, J, Phillips, L M, Toledo-Pereyra, L H

“…Little is known about the changes in the hepatic microcirculation and the leukocyte-endothelial adhesion processes during the early reperfusion period after…”
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Desethylaprophen: a metabolite of aprophen with antimuscarinic activities by Brown, N D, Smejkal, R M, Breuer, E, Doctor, B P, Chiang, P K

“…The metabolic fate of aprophen hydrochloride (2-diethylaminoethyl 2,2-diphenylpropionate) was studied in rats after intravenous administration. Both…”
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Dual blockade of P-selectin and (beta 2-integrin) in the liver inflammatory response after uncontrolled hemorrhagic shock by Anaya-Prado, Roberta, Toledo-Pereyra, Luis H, Collins, J T, Smejkal, R

“…BACKGROUND: Neutrophil infiltration is a characteristic feature of the hepatic injury associated with prolonged hypotension. Previous work has already stressed…”
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Dual blockade of P-selectin and beta2-integrin in the liver inflammatory response after uncontrolled hemorrhagic shock by Anaya-Prado, R, Toledo-Pereyra, L H, Collins, J T, Smejkal, R, McClaren, J, Crouch, L D, Ward, P A

“…Neutrophil infiltration is a characteristic feature of the hepatic injury associated with prolonged hypotension. Previous work has already stressed the…”
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Dual blockade of P-selectin and β 2-integrin in the liver inflammatory response after uncontrolled hemorrhagic shock by Anaya-Prado, Roberto, Toledo-Pereyra, Luis H, Collins, J.T, Smejkal, R, McClaren, J, Crouch, Larry D, Ward, Peter A

“…Background: Neutrophil infiltration is a characteristic feature of the hepatic injury associated with prolonged hypotension. Previous work has already stressed…”
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Muscarinic receptor subtype specificity of 5'-(isobutylthio)-adenosine (SIBA) and its analogs by Smejkal, R M, Abalis, I, Pankaskie, M C, Chiang, P K

“…1. 5'(Isobutylthio)-adenosine (SIBA) and its analogs, at 100 microM, inhibited [3H]N-methyl-scopolamine binding to homogenates of whole brain and cortex…”
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Injury severity scoring: a comparison of early clinical versus discharge diagnosis by Smejkal, R, Civil, I, Unkle, D, Ross, S E

“…The Abbreviated Injury Scale (AIS) and the Injury Severity Score (ISS) are objective means of assessing injury. Accepted methodology involves retrospective…”
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