Search Results - "Smart, E J"

Annexin 2-Caveolin 1 Complex Is a Target of Ezetimibe and Regulates Intestinal Cholesterol Transport by Smart, Eric J., De Rose, Robert A., Farber, Steven A., Brown, Donald D.

“…Modulation of cholesterol absorption in the intestine, the primary site of dietary cholesterol uptake in humans, can have profound clinical implications. We…”
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Palmitoylation of Caveolin-1 Is Required for Cholesterol Binding, Chaperone Complex Formation, and Rapid Transport of Cholesterol to Caveolae by Uittenbogaard, Annette, Smart, Eric J.

“…We previously demonstrated that a caveolin-chaperone complex transports newly synthesized cholesterol from the endoplasmic reticulum through the cytoplasm to…”
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A Detergent-Free Method for Purifying Caveolae Membrane from Tissue Culture Cells by Smart, Eric J., Ying, Yun-Shu, Mineo, Chieko, Richard G. W. Anderson

“…Current methods for purifying caveolae from tissue culture cells take advantage of the Triton X-100 insolubility of this membrane domain. To circumvent the use…”
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Effects of dairy food supplements on bone mineral density in teenage girls by MERRILEES, M. J, SMART, E. J, GILCHRIST, N. L, FRAMPTON, C, TURNER, J. G, HOOKE, E, MARCH, R. L, MAGUIRE, P

“…Background Bone mineral density (BMD) is largely genetically determined and this influence is most powerful in the period of rapid skeletal development in…”
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Macrophage scavenger receptors and foam cell formation by Villiers, Willem J. S., Smart, Eric J.

“…Scavenger receptors bind and internalize modified low‐density lipoprotein (LDL) and high‐density lipoprotein (HDL). Because the expression of scavenger…”
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Caveolin Moves from Caveolae to the Golgi Apparatus in Response to Cholesterol Oxidation by Smart, Eric J., Ying, Yun-Shu, Conrad, Patricia A., Richard G. W. Anderson

“…Caveolae are a membrane specialization used to internalize molecules by potocytosis. Caveolin, an integral membrane protein, is associated with the striated…”
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Protein Kinase C Activators Inhibit Receptor-Mediated Potocytosis by Preventing Internalization of Caveolae by Smart, Eric J., Foster, David C., Ying, Yun-Shu, Kamen, Barton A., Richard G. W. Anderson

“…Potocytosis is an endocytic pathway that utilizes glycosylphosphatidylinositol-anchored membrane proteins and caveolae to concentrate and internalize small…”
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Caveolin Cycles between Plasma Membrane Caveolae and the Golgi Complex by Microtubule-Dependent and Microtubule-Independent Steps by Conrad, Patricia A., Smart, Eric J., Ying, Yun-Shu, Richard G. W. Anderson, Bloom, George S.

“…Caveolin is a protein associated with the characteristic coats that decorate the cytoplasmic face of plasma membrane caveolae. Recently it was found that…”
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Hormonal Regulation of Caveolae Internalization by Smart, Eric J., Ying, Yun-shu, Richard G. W. Anderson

“…Caveolae undergo a cyclic transition from a flat segment of membrane to a vesicle that then returns to the cell surface. Here we present evidence that this…”
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Clustered Folate Receptors Deliver 5-Methyltetrahydrofolate to Cytoplasm of MA104 Cells by Smart, Eric J., Mineo, Chieko, Richard G. W. Anderson

“…Previously, a high affinity, glycosylphosphatidylinositol-anchored receptor for folate and a caveolae internalization cycle have been found necessary for…”
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Caveolins, Liquid-Ordered Domains, and Signal Transduction by Smart, Eric J., Graf, Gregory A., McNiven, Mark A., Sessa, William C., Engelman, Jeffrey A., Scherer, Philipp E., Okamoto, Takashi, Lisanti, Michael P.

“…Caveolae were originally identified as flask-shaped invaginations of the plasma membrane in endothelial and epithelial cells. Prior to the development of…”
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Class B Scavenger Receptors, Caveolae and Cholesterol Homeostasis by Graf, Gregory A, Matveev, Sergey V, Smart, Eric J

“…Class B scavenger receptors are predominately localized to cholesterol and sphingomyelin-enriched domains within the plasma membrane, called caveolae. Caveolae…”
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The prevalence of malnutrition in elderly hip fracture patients by Hanger, H C, Smart, E J, Merrilees, M J, Frampton, C M

“…To determine the prevalence of protein and energy malnutrition in elderly patients with a fracture of the proximal femur, in New Zealand. Consecutive elderly…”
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Purification and partial sequence analysis of a 37-kDa protein that inhibits phospholipase A2 activity from rat peritoneal exudates by Pepinsky, R B, Sinclair, L K, Browning, J L, Mattaliano, R J, Smart, J E, Chow, E P, Falbel, T, Ribolini, A, Garwin, J L, Wallner, B P

“…We have purified from rat peritoneal exudates a 37-kDa protein that inhibits phospholipase A2 activity. It is the predominant phospholipase inhibitor protein…”
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Characterization of a cytosolic heat-shock protein-caveolin chaperone complex. Involvement in cholesterol trafficking by Uittenbogaard, A, Ying, Y, Smart, E J

“…Caveolin is a 22-kDa protein that appears to play a critical role in regulating the cholesterol concentration of caveolae. Even though caveolin is thought to…”
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High Density Lipoprotein Prevents Oxidized Low Density Lipoprotein-induced Inhibition of Endothelial Nitric-oxide Synthase Localization and Activation in Caveolae by Uittenbogaard, Annette, Shaul, Philip W., Yuhanna, Ivan S., Blair, Alison, Smart, Eric J.

“…Oxidized LDL (oxLDL) depletes caveolae of cholesterol, resulting in the displacement of endothelial nitric-oxide synthase (eNOS) from caveolae and impaired…”
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Oxidized Low Density Lipoprotein Displaces Endothelial Nitric-oxide Synthase (eNOS) from Plasmalemmal Caveolae and Impairs eNOS Activation by Blair, Alison, Shaul, Philip W., Yuhanna, Ivan S., Conrad, Patricia A., Smart, Eric J.

“…Hypercholesterolemia-induced vascular disease and atherosclerosis are characterized by a decrease in the bioavailability of endothelium-derived nitric oxide…”
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Neutron detection via bubble chambers by Jordan, D.V., Ely, J.H., Peurrung, A.J., Bond, L.J., Collar, J.I., Flake, M., Knopf, M.A., Pitts, W.K., Shaver, M., Sonnenschein, A., Smart, J.E., Todd, L.C.

“…Research investigating the application of pressure-cycled bubble chambers to fast neutron detection is described. Experiments with a Halon-filled chamber…”
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HIV protease inhibitors promote atherosclerotic lesion formation independent of dyslipidemia by increasing CD36-dependent cholesteryl ester accumulation in macrophages by Dressman, James, Kincer, Jeanie, Matveev, Sergey V, Guo, Ling, Greenberg, Richard N, Guerin, Theresa, Meade, David, Li, Xiang-An, Zhu, Weifei, Uittenbogaard, Annette, Wilson, Melinda E, Smart, Eric J

“…Protease inhibitors decrease the viral load in HIV patients, however the patients develop hypertriglyceridemia, hypercholesterolemia, and atherosclerosis. It…”
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Specific Phospholipid Oxidation Products Inhibit Ligand Activation of Toll-Like Receptors 4 and 2 by Walton, Kimberly A, Cole, Amy L, Yeh, Michael, Subbanagounder, Ganesamoorthy, Krutzik, Stephan R, Modlin, Robert L, Lucas, Robert M, Nakai, Junko, Smart, Eric J, Vora, Deven K, Berliner, Judith A

“…OBJECTIVE—We have previously shown that phospholipid oxidation products of 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine (ox-PAPC) inhibit…”
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