Search Results - "Smallwood, Heather S."

Distinct Epigenetic Signatures Delineate Transcriptional Programs during Virus-Specific CD8+ T Cell Differentiation by Russ, Brendan E., Olshanksy, Moshe, Smallwood, Heather S., Li, Jasmine, Denton, Alice E., Prier, Julia E., Stock, Angus T., Croom, Hayley A., Cullen, Jolie G., Nguyen, Michelle L.T., Rowe, Stephanie, Olson, Matthew R., Finkelstein, David B., Kelso, Anne, Thomas, Paul G., Speed, Terry P., Rao, Sudha, Turner, Stephen J.

“…The molecular mechanisms that regulate the rapid transcriptional changes that occur during cytotoxic T lymphocyte (CTL) proliferation and differentiation in…”
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Targeting Metabolic Reprogramming by Influenza Infection for Therapeutic Intervention by Smallwood, Heather S., Duan, Susu, Morfouace, Marie, Rezinciuc, Svetlana, Shulkin, Barry L., Shelat, Anang, Zink, Erika E., Milasta, Sandra, Bajracharya, Resha, Oluwaseum, Ajayi J., Roussel, Martine F., Green, Douglas R., Pasa-Tolic, Ljiljana, Thomas, Paul G.

“…Influenza is a worldwide health and financial burden posing a significant risk to the immune-compromised, obese, diabetic, elderly, and pediatric populations…”
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Group IIA secreted phospholipase A2 (PLA2G2A) augments adipose tissue thermogenesis by Kuefner, Michael S., Stephenson, Erin, Savikj, Mladen, Smallwood, Heather S., Dong, Qingming, Payré, Christine, Lambeau, Gérard, Park, Edwards A.

“…Group IIA secreted phospholipase A2 (PLA2G2A) hydrolyzes glycerophospholipids at the sn‐2 position resulting in the release of fatty acids and…”
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Dynamic metabolic reprogramming in dendritic cells: An early response to influenza infection that is essential for effector function by Rezinciuc, Svetlana, Bezavada, Lavanya, Bahadoran, Azadeh, Duan, Susu, Wang, Ruoning, Lopez-Ferrer, Daniel, Finkelstein, David, McGargill, Maureen A, Green, Douglas R, Pasa-Tolic, Ljiljana, Smallwood, Heather S

“…Infection with the influenza virus triggers an innate immune response that initiates the adaptive response to halt viral replication and spread. However, the…”
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Mapping Influenza-Induced Posttranslational Modifications on Histones from CD8+ T Cells by Rezinciuc, Svetlana, Tian, Zhixin, Wu, Si, Hengel, Shawna, Pasa-Tolic, Ljiljana, Smallwood, Heather S

“…T cell function is determined by transcriptional networks that are regulated by epigenetic programming via posttranslational modifications (PTMs) to histone…”
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Aging Enhances the Production of Reactive Oxygen Species and Bactericidal Activity in Peritoneal Macrophages by Upregulating Classical Activation Pathways by Smallwood, Heather S, López-Ferrer, Daniel, Squier, Thomas C

“…Maintenance of macrophages in their basal state and their rapid activation in response to pathogen detection are central to the innate immune system, acting to…”
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Diverse heterologous primary infections radically alter immunodominance hierarchies and clinical outcomes following H7N9 influenza challenge in mice by Duan, Susu, Meliopoulos, Victoria A, McClaren, Jennifer L, Guo, Xi-Zhi J, Sanders, Catherine J, Smallwood, Heather S, Webby, Richard J, Schultz-Cherry, Stacey L, Doherty, Peter C, Thomas, Paul G

“…The recent emergence of a novel H7N9 influenza A virus (IAV) causing severe human infections in China raises concerns about a possible pandemic. The lack of…”
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Fueling influenza and the immune response: Implications for metabolic reprogramming during influenza infection and immunometabolism by Bahadoran, Azadeh, Bezavada, Lavanya, Smallwood, Heather S.

“…Recent studies support the notion that glycolysis and oxidative phosphorylation are rheostats in immune cells whose bioenergetics have functional outputs in…”
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Proteomic Investigation of the Time Course Responses of RAW 264.7 Macrophages to Infection with Salmonella enterica by LIANG SHI, CHOWDHURY, Saiful M, ADKINS, Joshua N, SMALLWOOD, Heather S, YOON, Hyunjin, MOTTAZ-BREWER, Heather M, NORBECK, Angela D, MCDERMOTT, Jason E, CLAUSS, Therese R. W, HEFFRON, Fred, SMITH, Richard D

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Distinct Epigenetic Signatures Delineate Transcriptional Programs during Virus-Specific CD8+ T Cell Differentiation by Russ, Brendan E., Olshanksy, Moshe, Smallwood, Heather S., Li, Jasmine, Denton, Alice E., Prier, Julia E., Stock, Angus T., Croom, Hayley A., Cullen, Jolie G., Nguyen, Michelle L.T., Rowe, Stephanie, Olson, Matthew R., Finkelstein, David B., Kelso, Anne, Thomas, Paul G., Speed, Terry P., Rao, Sudha, Turner, Stephen J.

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Seasonal influenza vaccination is the strongest correlate of cross-reactive antibody responses in migratory bird handlers by Oshansky, Christine M, Wong, Sook-San, Jeevan, Trushar, Smallwood, Heather S, Webby, Richard J, Shafir, Shira C, Thomas, Paul G

“…Avian species are reservoirs of influenza A viruses and could harbor viruses with significant pandemic potential. We examined the antibody and cellular immune…”
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Identification of a Denitrase Activity against Calmodulin in Activated Macrophages Using High-Field Liquid Chromatography−FTICR Mass Spectrometry by Smallwood, Heather S, Lourette, Natacha M, Boschek, Curt B, Bigelow, Diana J, Smith, Richard D, Paša-Tolić, Ljiljana, Squier, Thomas C

“…We have identified a denitrase activity in macrophages that is upregulated following macrophage activation, which is shown by mass spectrometry to recognize…”
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S2131 Gastrointestinal Manifestations as an Indicator for Clinically Severe COVID-19 by Hundman, Chloe, Smallwood, Heather S., Wan, Jim Y., Goedecke, Patricia J., Green, Amanda

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Influenza A virus directly modulates mouse eosinophil responses by LeMessurier, Kim S., Rooney, Robert, Ghoneim, Hazem E., Liu, Baoming, Li, Kui, Smallwood, Heather S., Samarasinghe, Amali E.

“…Allergic asthma and influenza are common respiratory diseases with a high probability of co‐occurrence. During the 2009 influenza pandemic, hospitalized…”
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Myeloid Slc2a1 -Deficient Murine Model Revealed Macrophage Activation and Metabolic Phenotype Are Fueled by GLUT1 by Freemerman, Alex J, Zhao, Liyang, Pingili, Ajeeth K, Teng, Bin, Cozzo, Alyssa J, Fuller, Ashley M, Johnson, Amy R, Milner, J Justin, Lim, Maili F, Galanko, Joseph A, Beck, Melinda A, Bear, James E, Rotty, Jeremy D, Bezavada, Lavanya, Smallwood, Heather S, Puchowicz, Michelle A, Liu, Juan, Locasale, Jason W, Lee, Douglas P, Bennett, Brian J, Abel, E Dale, Rathmell, Jeff C, Makowski, Liza

“…Macrophages (MΦs) are heterogeneous and metabolically flexible, with metabolism strongly affecting immune activation. A classic response to proinflammatory…”
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Pharmacologic activation of estrogen receptor β increases mitochondrial function, energy expenditure, and brown adipose tissue by Ponnusamy, Suriyan, Tran, Quynh T, Harvey, Innocence, Smallwood, Heather S, Thiyagarajan, Thirumagal, Banerjee, Souvik, Johnson, Daniel L, Dalton, James T, Sullivan, Ryan D, Miller, Duane D, Bridges, Dave, Narayanan, Ramesh

“…Most satiety-inducing obesity therapeutics, despite modest efficacy, have safety concerns that underscore the need for effective peripherally acting drugs. An…”
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Functional link between TNF biosynthesis and CaM-dependent activation of inducible nitric oxide synthase in RAW 264.7 macrophages by Weber, Thomas J, Smallwood, Heather S, Kathmann, Loel E, Markillie, Lye Meng, Squier, Thomas C, Thrall, Brian D

“…Inflammatory responses stimulated by bacterial endotoxin LPS involve Ca2+-mediated signaling, yet the cellular sensors that determine cell fate in response to…”
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Pharmacologic activation of estrogen receptor α increases mitochondrial function, energy expenditure, and brown adipose tissue by Ponnusamy, Suriyan, Tran, Quynh T., Harvey, Innocence, Smallwood, Heather S., Thiyagarajan, Thirumagal, Banerjee, Souvik, Johnson, Daniel L., Dalton, James T., Sullivan, Ryan D., Miller, Duane D., Bridges, Dave, Narayanan, Ramesh

“…Most satiety‐inducing obesity therapeutics, despitemodest efficacy, have safety concerns that underscore the need for effective peripherally acting drugs. An…”
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Proteomic Analysis of Salmonella enterica Serovar Typhimurium Isolated from RAW 264.7 Macrophages: IDENTIFICATION OF A NOVEL PROTEIN THAT CONTRIBUTES TO THE REPLICATION OF SEROVAR TYPHIMURIUM INSIDE MACROPHAGES by Shi, Liang, Adkins, Joshua N, Coleman, James R, Schepmoes, Athena A, Dohnkova, Alice, Mottaz, Heather M, Norbeck, Angela D, Purvine, Samuel O, Manes, Nathan P, Smallwood, Heather S, Wang, Haixing, Forbes, John, Gros, Philippe, Uzzau, Sergio, Rodland, Karin D, Heffron, Fred, Smith, Richard D, Squier, Thomas C

“…To evade host resistance mechanisms, Salmonella enterica serovar Typhimurium (STM), a facultative intracellular pathogen, must alter its proteome following…”
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Oxidation of Met144 and Met145 in Calmodulin Blocks Calmodulin Dependent Activation of the Plasma Membrane Ca-ATPase by Bartlett, Ryan K, Bieber Urbauer, Ramona J, Anbanandam, Asokan, Smallwood, Heather S, Urbauer, Jeffrey L, Squier, Thomas C

“…Methionine oxidation in calmodulin (CaM) isolated from senescent brain results in an inability to fully activate the plasma membrane (PM) Ca-ATPase, which may…”
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