Search Results - "Smalling, R"

Final results of the can Routine Ultrasound Influence Stent Expansion (CRUISE) study by FITZGERALD, P. J, OSHIMA, A, MOSES, J. W, OESTERLE, S. N, OVERLIE, P. A, PEPINE, C. J, SAFIAN, R. D, SHANI, J, SIMONTON, C. A, SMALLING, R. W, TEIRSTEIN, P. S, ZIDAR, J. P, HAYASE, M, YEUNG, A. C, KUNTZ, R. E, YOCK, P. G, METZ, J. A, BAILEY, S. R, BAIM, D. S, CLEMAN, M. W, DEUTSCH, E, DIVER, D. J, LEON, M. B

“…Intravascular ultrasound (IVUS) can assess stent geometry more accurately than angiography. Several studies have demonstrated that the degree of stent…”
Get full text

A Comparison of Reteplase with Alteplase for Acute Myocardial Infarction by Topol, E, Califf, R, Ohman, E, Skene, A

“…Recent trials have confirmed the importance of achieving early, complete, and sustained reperfusion after acute myocardial infarction. 1 – 3 In the Global…”
Get full text

Randomized comparison of coronary thrombolysis achieved with double-bolus reteplase (recombinant plasminogen activator) and front-loaded, accelerated alteplase (recombinant tissue plasminogen activator) in patients with acute myocardial infarction by BODE, C, SMALLING, R. W, WEAVER, W. D, BERG, G, BURNETT, C, LORCH, G, KALBFLEISCH, J. M, CHERNOFF, R, CHRISTIE, L. G, FELDMAN, R. L, SEALS, A

“…Background The therapeutic benefit of thrombolytic therapy has been shown to correlate directly with completeness (TIMI grade 3 flow) and speed of reperfusion…”
Get full text

Evaluation of a weight-adjusted single-bolus plasminogen activator in patients with myocardial infarction: A double-blind, randomized angiographic trial of lanoteplase versus alteplase by DEN HEIJER, P, VERMEER, F, BRINKER, J, DAVIES, R. F, SMALLING, R. W, WALLENTIN, L, CASPI, A, PANGERL, A, TRICKETT, L, HAUCK, C, HENRY, D, CHEW, P, AMBROSIONI, E, SADOWSKI, Z, LOPEZ-SENDON, J. L, VON ESSEN, R, BEAUFILS, P, THADANI, U, ADGEY, J, PIERARD, L

“…Lanoteplase (nPA) is a rationally designed variant of tissue plasminogen activator with greater fibrinolytic potency and slower plasma clearance than…”
Get full text

Adenosine use during aortocoronary vein graft interventions reverses but does not prevent the slow-no reflow phenomenon by Sdringola, S., Assali, A., Ghani, M., Yepes, A., Rosales, O., Schroth, G.W., Fujise, Ken, Anderson, H.V., Smalling, R.W.

“…Slow or no reflow (SNR) complicates 10–15% of cases of percutaneous intervention (PI) in saphenous vein bypass graft (SVG). To date there have been limited…”
Get full text

Pharmacological and clinical impact of the unique molecular structure of a new plasminogen activator by Smalling, R W

“…Thrombolytic therapy has been recognized as a significant improvement in the management of acute myocardial infarction. Thrombolytic agents however have been…”
Get full text

More rapid, complete, and stable coronary thrombolysis with bolus administration of reteplase compared with alteplase infusion in acute myocardial infarction by SMALLING, R. W, BODE, C, KALBFLEISCH, J, SEMI SEN, LIMBOURG, P, FORYCKI, F, HABIB, G, FELDMAN, R, HOHNLOSER, S, SEALS, A

“…Background Early restoration and maintenance of normal (TIMI 3) blood flow during acute myocardial infarction is critical for optimal preservation of left…”
Get full text

Coronary thrombi increase PTCA risk : angioscopy as a clinical tool by WHITE, C. J, RAMEE, S. R, BONAN, R, WALTER, P. D, SMALLING, R. W, COLLINS, T. J, ESCOBAR, A. E, KARSAN, A, SHAW, D, JAIN, S. P, BASS, T. A, HEUSER, R. R, TEIRSTEIN, P. S

“…The presence of angiographically identified intracoronary thrombus has been variably associated with complications after coronary angioplasty. Angiography has…”
Get full text

Molecular Biology of Plasminogen Activators: What Are the Clinical Implications of Drug Design? by Smalling, Richard W

“…The initial work on thrombolytic therapy for acute myocardial infarction (AMI) focused on intracoronary administration of streptokinase. Continuing research…”
Get full text

Infrapopliteal Transcatheter Interventions for Limb Salvage in Diabetic Patients: Importance of Aggressive Interventional Approach and Role of Transcutaneous Oximetry by Hanna, George P, Fujise, Ken, Kjellgren, Olle, Feld, Steven, Fife, Caroline, Schroth, George, Clanton, Tom, Anderson, Vernon, Smalling, Richard W

“…Objectives. This study sought to determine whether infrapopliteal transcatheter interventions can salvage ischemic limbs in diabetic patients referred for…”
Get full text

Transseptal puncture guided by intracardiac echocardiography during percutaneous transvenous mitral commissurotomy in patients with distorted anatomy of the fossa ovalis by Cafri, C., de la Guardia, B., Barasch, E., Brink, J., Smalling, R.W.

“…Positioning of the transseptal needle during percutaneous transvenous mitral commissurotomy (PTMV) can become a difficult and risky procedure when distortion…”
Get full text

The future of thrombolysis in the treatment of acute myocardial infarction by Bode, C., Runge, M. S., Smalling, R. W.

“…The ability of thrombolytic therapy to lower mortality in patients with acute myocardial infarction was first demonstrated in 1986 by the Gruppo Italiano per…”
Get full text

Assessment of coronary artery disease severity by positron emission tomography: comparison with quantitative arteriography in 193 patients by DEMER, L. L, GOULD, K. L, GOLDSTEIN, R. A, KIRKEEIDE, R. L, MULLANI, N. A, SMALLING, R. W, NISHIKAWA, A, MERHIGE, M. E

“…To assess the accuracy of positron emission tomography (PET) for evaluation of coronary artery disease (CAD), cardiac PET perfusion images were obtained at…”
Get full text

Cloning and Expression of the Human Erythropoietin Gene by Lin, Fu-Kuen, Suggs, Sidney, Lin, Chi-Hwei, Browne, Jeffrey K., Smalling, Ralph, Egrie, Joan C., Chen, Kenneth K., Fox, Gary M., Martin, Frank, Stabinsky, Zippora, Badrawi, Sayed M., Lai, Por-Hsiung, Goldwasser, Eugene

“…The human erythropoietin gene has been isolated from a genomic phage library by using mixed 20-mer and 17-mer oligonucleotide probes. The entire coding region…”
Get full text

Patterns in visual interpretation of coronary arteriograms as detected by quantitative coronary arteriography by Fleming, Richard M., Kirkeeide, Richard L., Smalling, Richard W., Gould, K.Lance, Stuart, Yvonne

“…In part 1 of a three-part study, 14 novice readers and 6 experienced cardiologists interpreted phantom images of known stenosis severity. No difference between…”
Get full text

Improved regional myocardial blood flow, left ventricular unloading, and infarct salvage using an axial-flow, transvalvular left ventricular assist device : a comparison with intra-aortic balloon counterpulsation and reperfusion alone in a canine infarction model by SMALLING, R. W, CASSIDY, D. B, BARRETT, R, LACHTERMAN, B, FELLI, P, AMIRIAN, J

“…It has been suggested that left ventricular unloading at the time of reperfusion provides superior infarct salvage over reperfusion alone. The purpose of this…”
Get full text

Myocardial Metabolism of Fluorodeoxyglucose Compared to Cell Membrane Integrity for the Potassium Analogue Rubidium-82 for Assessing Infarct Size in Man by PET by Gould, K. Lance, Yoshida, Katsuya, Hess, Mary Jane, Haynie, Mary, Mullani, Nizar, Smalling, Richard W

“…Potassium loss from damaged myocardial cells is linearly related to CPK enzyme loss reflecting extent of necrosis. The potassium analog, rubidium-82 (82Rb), is…”
Get full text

Intracoronary adenosine administered during percutaneous intervention in acute myocardial infarction and reduction in the incidence of "no reflow" phenomenon by Assali, Abid R., Sdringola, Stefano, Ghani, Mohammad, Denkats, Ali E., Yepes, Armando, Hanna, George P., Schroth, George, Fujise, Ken, Anderson, H. Vernon, Smalling, Richard W., Rosales, Oscar R.

“…Percutaneous intervention in acute myocardial infarction has been associated with a high incidence of “no reflow,” ranging from 11% to 30%, with an increased…”
Get full text

Intravascular photoacoustic imaging of lipid in atherosclerotic plaques in the presence of luminal blood by Wang, Bo, Karpiouk, Andrei, Yeager, Doug, Amirian, James, Litovsky, Silvio, Smalling, Richard, Emelianov, Stanislav

“…Intravascular photoacoustic (IVPA) imaging can characterize atherosclerotic plaque composition on the basis of the optical absorption contrast between…”
Get more information

Risk assessment of slow or no-reflow phenomenon in aortocoronary vein graft percutaneous intervention by Sdringola, Stefano, Assali, Abid R., Ghani, Mohammed, Moustapha, Ali, Achour, Hela, Yusuf, S. Wamique, Fujise, Ken, Rosales, Oscar, Schroth, George W., Anderson, H. Vernon, Smalling, Richard W.

“…Slow or no‐reflow phenomenon (SNR) complicates 10%–15% of cases of percutaneous intervention (PCI) in aortocoronary saphenous vein grafts (SVG). At present,…”
Get full text