Search Results - "Smalley Rumfield, Claire"

Therapeutic Vaccines for HPV-Associated Malignancies by Rumfield, Claire Smalley, Roller, Nicholas, Pellom, Samuel Troy, Schlom, Jeffrey, Jochems, Caroline

“…Human papillomavirus (HPV)-related malignancies are responsible for almost all cases of cervical cancer in women, and over 50% of all cases of head and neck…”
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Immunomodulation to enhance the efficacy of an HPV therapeutic vaccine by Smalley Rumfield, Claire, Pellom, Samuel T, Morillon II, Y Maurice, Schlom, Jeffrey, Jochems, Caroline

“…BackgroundWhile prophylactic human papillomavirus (HPV) vaccines will certainly reduce the incidence of HPV-associated cancers, these malignancies remain a…”
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The multi-functionality of N-809, a novel fusion protein encompassing anti-PD-L1 and the IL-15 superagonist fusion complex by Jochems, Caroline, Tritsch, Sarah R., Knudson, Karin M., Gameiro, Sofia R., Rumfield, Claire Smalley, Pellom, Samuel T., Morillon, Y. Maurice, Newman, Robby, Marcus, Warren, Szeto, Christopher, Rabizadeh, Shahrooz, Wong, Hing C., Soon-Shiong, Patrick, Schlom, Jeffrey

“…Here we describe a novel bifunctional fusion protein, designated N-809. This molecule comprises the IL-15/IL15Rα superagonist complex containing the Fc-domain…”
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Characterization of recombinant gorilla adenovirus HPV therapeutic vaccine PRGN-2009 by Pellom, Samuel T, Smalley Rumfield, Claire, Morillon, 2nd, Y Maurice, Roller, Nicholas, Poppe, Lisa K, Brough, Douglas E, Sabzevari, Helen, Schlom, Jeffrey, Jochems, Caroline

“…There are approximately 44,000 cases of human papillomavirus-associated (HPV-associated) cancer each year in the United States, most commonly caused by HPV…”
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The Use of a Humanized NSG-β2m -/- Model for Investigation of Immune and Anti-tumor Effects Mediated by the Bifunctional Immunotherapeutic Bintrafusp Alfa by Morillon, Y Maurice Ii, Smalley Rumfield, Claire, Pellom, Samuel T, Sabzevari, Ariana, Roller, Nicholas T, Horn, Lucas A, Jochems, Caroline, Palena, Claudia, Greiner, John W, Schlom, Jeffrey

“…The lack of serial biopsies in patients with a range of carcinomas has been one obstacle in our understanding of the mechanism of action of immuno-oncology…”
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Anti-tumor efficacy and immune responses induced by a novel therapeutic HPV-specific gorilla adenovirus off-the-shelf immunotherapeutic (PRGN-2009) by Pellom, Samuel Troy, Rumfield, Claire Smalley, Morillon, Yves Maurice, Roller, Nicholas, Brough, Douglas, Sabzevari, Helen, Greiner, Jack, Schlom, Jeffrey, Jochems, Caroline

“…Abstract There are about 44,000 cases of Human Papilloma Virus (HPV) associated cancer each year in the US, most commonly caused by HPV 16 and 18. Prophylactic…”
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