Search Results - "Small, J V"

Interplay between Rac and Rho in the control of substrate contact dynamics by Rottner, K., Hall, A., Small, J.V.

“…Background: Substrate anchorage and cell locomotion entail the initiation and development of different classes of contact sites, which are associated with the…”
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Role of desmin in active force transmission and maintenance of structure during growth of urinary bladder by Scott, R Sjuve, Li, Z, Paulin, D, Uvelius, B, Small, J V, Arner, A

“…Role of the intermediate filament protein desmin in hypertrophy of smooth muscle was examined in desmin-deficient mice (Des(-/-)). A partial obstruction of the…”
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Zyxin is not colocalized with vasodilator-stimulated phosphoprotein (VASP) at lamellipodial tips and exhibits different dynamics to vinculin, paxillin, and VASP in focal adhesions by Rottner, K, Krause, M, Gimona, M, Small, J V, Wehland, J

“…Actin polymerization is accompanied by the formation of protein complexes that link extracellular signals to sites of actin assembly such as membrane ruffles…”
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Hyaluronic Acid (HA) Binding to CD44 Activates Rac1 and Induces Lamellipodia Outgrowth by Oliferenko, Snezhana, Kaverina, Irina, Small, J. Victor, Huber, Lukas A.

“…Both cell adhesion protein CD44 and its main ligand hyaluronic acid (HA) are thought to be involved in several processes ultimately requiring cytoskeleton…”
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The cytoskeleton of the vertebrate smooth muscle cell by SMALL, J. V, GIMONA, M

“…Smooth muscle cells possess a structural lattice composed of two primary parts: the ‘cytoskeleton’ that pervades the cytoplasm and the ‘membrane skeleton’ that…”
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Actin Filament Organization in the Fish Keratocyte Lamellipodium by Small, J. Victor, Herzog, Monika, Anderson, Kurt

“…From recent studies of locomoting fish keratocytes it was proposed that the dynamic turnover of actin filaments takes place by a nucleation-release mechanism,…”
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Coordination of Protrusion and Translocation of the Keratocyte Involves Rolling of the Cell Body by Anderson, K. I., Wang, Yu-Li, Small, J. V.

“…We have investigated the relationship between lamellipodium protrusion and forward translocation of the cell body in the rapidly moving keratocyte. It is first…”
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The SM 22 promoter directs tissue-specific expression in arterial but not in venous or visceral smooth muscle cells in transgenic mice by Moessler, H, Mericskay, M, Li, Z, Nagl, S, Paulin, D, Small, J V

“…The transcriptional signals underlying smooth muscle differentiation are currently unknown. We report here the complete sequence and characterization of the…”
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Filopodia formation induced by active mDia2/Drf3 by BLOCK, J, STRADAL, T.E.B, HÄNISCH, J, GEFFERS, R, KÖSTLER, S.A, URBAN, E, SMALL, J.V, ROTTNER, K, FAIX, J

“…Filopodia are rod-shaped cell surface protrusions composed of a parallel bundle of actin filaments. Since filopodia frequently emanate from lamellipodia, it…”
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Complementary Distributions of Vinculin and Dystrophin Define Two Distinct Sarcolemma Domains in Smooth Muscle by North, Alison J., Galazkiewicz, Barbara, Byers, Timothy J., Glenney, John R., Small, J. Victor

“…The sarcolemma of the smooth muscle cell displays two alternating structural domains in the electron microscope: densely-staining plaques that correspond to…”
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Contact Formation during Fibroblast Locomotion: Involvement of Membrane Ruffles and Microtubules by Rinnerthaler, G., Geiger, B., Small, J. V.

“…We have correlated the motility of the leading edge of fibroblasts, monitored by phase-contrast cinematography, with the relative distributions of several…”
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Mechanical alterations in smooth muscle from mice lacking desmin by Sjuve, R, Arner, A, Li, Z, Mies, B, Paulin, D, Schmittner, M, Small, J V

“…Mice with a null mutation introduced in the desmin gene were used to study the mechanical role of intermediate filaments in smooth muscle cells. Vas deferens…”
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Nascent Focal Adhesions Are Responsible for the Generation of Strong Propulsive Forces in Migrating Fibroblasts by Beningo, Karen A., Dembo, Micah, Kaverina, Irina, Small, J. Victor, Wang, Yu-li

“…Fibroblast migration involves complex mechanical interactions with the underlying substrate. Although tight substrate contact at focal adhesions has been…”
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Organization of Actin in the Leading Edge of Cultured Cells: Influence of Osmium Tetroxide and Dehydration on the Ultrastructure of Actin Meshworks by Small, J. V.

“…The ordered structure of the leading edge (lamellipodium) of cultured fibroblasts is readily revealed in cells extracted briefly in Triton X-100-glutaraldehyde…”
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Actin isoform compartments in chicken gizzard smooth muscle cells by NORTH, A. J, GIMONA, M, LANDO, Z, SMALL, J. V

“…Differentiated smooth muscle cells typically contain a mixture of muscle (alpha and gamma) and cytoplasmic (beta and gamma) actin isoforms. Of the cytoplasmic…”
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Mammalian calponin: Identification and expression of genetic variants by Strasser, Peter, Gimona, Mario, Moessler, Herbert, Herzog, Monika, Small, J.Victor

“…Calponin is a smooth muscle specific, actin-, tropomyosin- and calmodulin-binding protein thought to be involved in some way in the regulation or modulation of…”
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Microtubule Targeting of Substrate Contacts Promotes Their Relaxation and Dissociation by Kaverina, Irina, Krylyshkina, Olga, Small, J. Victor

“…We recently showed that substrate contact sites in living fibroblasts are specifically targeted by microtubules (Kaverina, I., K. Rottner, and J.V. Small…”
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Unravelling the structure of the lamellipodium by SMALL, J.V, AUINGER, S, NEMETHOVA, M, KOESTLER, S, GOLDIE, K.N, HOENGER, A, RESCH, G.P

“…Pushing at the cell front is the business of lamellipodia and understanding how lamellipodia function requires knowledge of their structural organization…”
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Calponin is localised in both the contractile apparatus and the cytoskeleton of smooth muscle cells by NORTH, A. J, GIMONA, M, CROSS, R. A, SMALL, J. V

“…Calponin and caldesmon are two thin filament-binding proteins found in smooth muscle that have both been attributed a role in modulating the interaction of…”
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VASP dynamics during lamellipodia protrusion by Rottner, Klemens, Behrendt, Barbara, Small, J.Victor, Wehland, Jurgen

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