Search Results - "Smailovic, Una"
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Neurophysiological Markers of Alzheimer’s Disease: Quantitative EEG Approach
Published in Neurology and therapy (01-12-2019)“…Currently established and employed biomarkers of Alzheimer's disease (AD) predominantly mirror AD-associated molecular and structural brain changes. While they…”
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EEG time signature in Alzheimer´s disease: Functional brain networks falling apart
Published in NeuroImage clinical (2019)“…•EEG microstate topographies differ between controls and memory clinic patients.•Microstate parameters differ in a gradient-like manner in SCD, MCI and AD…”
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Cerebrospinal fluid neurogranin in an inducible mouse model of neurodegeneration: A translatable marker of synaptic degeneration
Published in Neurobiology of disease (01-02-2020)“…Synapse impairment is thought to be an early event in Alzheimer's disease (AD); dysfunction and loss of synapses are linked to cognitive symptoms that precede…”
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Decreased Electroencephalography Global Field Synchronization in Slow-Frequency Bands Characterizes Synaptic Dysfunction in Amnestic Subtypes of Mild Cognitive Impairment
Published in Frontiers in aging neuroscience (2022)“…Mild cognitive impairment (MCI) is highly prevalent in a memory clinic setting and is heterogeneous regarding its clinical presentation, underlying…”
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Decreased Global EEG Synchronization in Amyloid Positive Mild Cognitive Impairment and Alzheimer’s Disease Patients—Relationship to APOE ε4
Published in Brain sciences (2021)“…The apolipoprotein E (APOE) ε4 allele is a risk factor for Alzheimer’s disease (AD) that has been linked to changes in brain structure and function as well as…”
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Quantitative EEG power and synchronization correlate with Alzheimer's disease CSF biomarkers
Published in Neurobiology of aging (01-03-2018)“…Synaptic dysfunction is the best anatomical correlate of early cognitive impairment in Alzheimer's disease (AD). Electroencephalography (EEG) directly reflects…”
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Past, present and future EEG in the clinical workup of dementias
Published in Psychiatry research. Neuroimaging (30-12-2020)“…•EEG is generally unlikely to become a useful biomarker of some proteinopathies.•EEG can trace the burden of plasticity and repair, cognitive reserve, and…”
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Multimodal Phenotyping of Synaptic Damage in Alzheimer’s Disease: Translational Perspective with Focus on Quantitative EEG
Published 01-01-2021“…Alzheimer’s disease (AD) is a progressive neurodegenerative disorder and the most common form of dementia. Accumulation of AD-associated pathology in the brain…”
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APP accumulates with presynaptic proteins around amyloid plaques: A role for presynaptic mechanisms in Alzheimer's disease?
Published in Alzheimer's & dementia (01-11-2022)“…In Alzheimer's disease (AD), the distribution of the amyloid precursor protein (APP) and its fragments other than amyloid beta, has not been fully…”
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Translational potential of mouse CSF biomarkers in Alzheimer’s disease: Association of CSF neurogranin with tau, NFL and amyloid pathology in APP knock‐in mouse models: Molecular and cell biology/synaptic disruption
Published in Alzheimer's & dementia (01-12-2020)“…Abstract Background Alzheimer’s disease (AD) is characterized by early and progressive synaptic dysfunction and loss that are closely related to cognitive…”
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Translational potential of mouse CSF biomarkers in Alzheimer’s disease: Association of CSF neurogranin with tau, NFL and amyloid pathology in APP knock‐in mouse models
Published in Alzheimer's & dementia (01-12-2020)“…Background Alzheimer’s disease (AD) is characterized by early and progressive synaptic dysfunction and loss that are closely related to cognitive impairment in…”
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EEG time signature in Alzheimer's disease: Functional brain networks falling apart
Published in NeuroImage clinical (2019)“…Spontaneous mental activity is characterized by dynamic alterations of discrete and stabile brain states called functional microstates that are thought to…”
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Multi-target iron-chelators improve memory loss in a rat model of sporadic Alzheimer's disease
Published in Life sciences (1973) (01-09-2015)“…Novel effective treatment is urgently needed for sporadic Alzheimer's disease (sAD). M30 ([5-(N-methyl-N-propargylaminomethyl)-8-hydroxyquinoline]) and HLA-20…”
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Quantitative EEG power and synchronization correlate with Alzheimer's disease CSF biomarkers (vol 63, pg 88, 2018)
Published in NEUROBIOLOGY OF AGING (01-07-2020)Get full text
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Decorin is an early CSF biomarker of Alzheimer’s Aβ amyloidosis
Published in Alzheimer's & dementia (01-12-2021)“…Background Alzheimer’s disease (AD) brains are characterized by extracellular amyloid‐beta (Aβ) deposition and autophagy dysregulation. Here we aimed at…”
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EEG-Meta-Microstates: Towards a More Objective Use of Resting-State EEG Microstate Findings Across Studies
Published in Brain topography (01-03-2024)“…Over the last decade, EEG resting-state microstate analysis has evolved from a niche existence to a widely used and well-accepted methodology. The rapidly…”
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Increased CSF-decorin predicts brain pathological changes driven by Alzheimer's A[beta] amyloidosis
Published in Acta neuropathologica communications (04-07-2022)“…Cerebrospinal fluid (CSF) biomarkers play an important role in diagnosing Alzheimer's disease (AD) which is characterized by amyloid-[beta] (A[beta])…”
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Increased CSF-decorin predicts brain pathological changes driven by Alzheimer’s Aβ amyloidosis
Published in Acta neuropathologica communications (2022)“…Abstract Cerebrospinal fluid (CSF) biomarkers play an important role in diagnosing Alzheimer’s disease (AD) which is characterized by amyloid-β (Aβ)…”
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Journal Article