Search Results - "Smaardijk, Susanne"
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Store-independent coupling between the Secretory Pathway Ca2+ transport ATPase SPCA1 and Orai1 in Golgi stress and Hailey-Hailey disease
Published in Biochimica et biophysica acta. Molecular cell research (01-06-2018)“…The Secretory Pathway Ca2+ ATPases SPCA1 and SPCA2 transport Ca2+ and Mn2+ into the Golgi and Secretory Pathway. SPCA2 mediates store-independent Ca2+ entry…”
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SPCA2 couples Ca2+ influx via Orai1 to Ca2+ uptake into the Golgi/secretory pathway
Published in Tissue & cell (01-04-2017)“…Graphical abstract…”
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Structures of the heart specific SERCA2a Ca2+‐ATPase
Published in The EMBO journal (01-03-2019)“…The sarcoplasmic/endoplasmic reticulum Ca 2+ ‐ATPase 2a (SERCA2a) performs active reuptake of cytoplasmic Ca 2+ and is a major regulator of cardiac muscle…”
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4
Store-independent coupling between the Secretory Pathway Ca 2+ transport ATPase SPCA1 and Orai1 in Golgi stress and Hailey-Hailey disease
Published in Biochimica et biophysica acta. Molecular cell research (01-06-2018)“…The Secretory Pathway Ca ATPases SPCA1 and SPCA2 transport Ca and Mn into the Golgi and Secretory Pathway. SPCA2 mediates store-independent Ca entry (SICE) via…”
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Structure/activity relationship of thapsigargin inhibition on the purified Golgi/secretory pathway Ca2+/Mn2+-transport ATPase (SPCA1a)
Published in The Journal of biological chemistry (28-04-2017)“…The Golgi/secretory pathway Ca2+/Mn2+-transport ATPase (SPCA1a) is implicated in breast cancer and Hailey-Hailey disease. Here, we purified recombinant human…”
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Structure/Function Analysis of the Ubiquitous Secretory Pathway Ca2+ Pump SPCA1a
Published in Biophysical journal (28-01-2014)Get full text
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SPCA2 couples Ca 2+ influx via Orai1 to Ca 2+ uptake into the Golgi/secretory pathway
Published in Tissue & cell (01-04-2017)“…Dysregulation of the Golgi/Secretory Pathway Ca transport ATPase SPCA2 is implicated in breast cancer. During lactation and in luminal breast cancer types,…”
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SPCA2 couples Ca^sup 2+^ influx via Orai1 to Ca^sup 2+^ uptake into the Golgi/secretory pathway
Published in Tissue & cell (01-04-2017)“…Dysregulation of the Golgi/Secretory Pathway Ca2+ transport ATPase SPCA2 is implicated in breast cancer. During lactation and in luminal breast cancer types,…”
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9
Structures of the heart specific SERCA 2a Ca 2+ ‐ ATP ase
Published in The EMBO journal (01-03-2019)Get full text
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10
An N-terminal Ca2+-binding motif regulates the secretory pathway Ca2+/Mn2+-transport ATPase SPCA1
Published in The Journal of biological chemistry (10-05-2019)“…The Ca2+/Mn2+ transport ATPases 1a and 2 (SPCA1a/2) are closely related to the sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA) and are implicated in breast…”
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An N-terminal Ca 2+ -binding motif regulates the secretory pathway Ca 2+ /Mn 2+ -transport ATPase SPCA1
Published in The Journal of biological chemistry (10-05-2019)“…The Ca /Mn transport ATPases 1a and 2 (SPCA1a/2) are closely related to the sarco(endo)plasmic reticulum Ca -ATPase (SERCA) and are implicated in breast cancer…”
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12
Structures of the heart specific SERCA2a Ca 2+ -ATPase
Published in The EMBO journal (01-03-2019)“…The sarcoplasmic/endoplasmic reticulum Ca -ATPase 2a (SERCA2a) performs active reuptake of cytoplasmic Ca and is a major regulator of cardiac muscle…”
Get full text
Journal Article -
13
Structure/activity relationship of thapsigargin inhibition on the purified Golgi/secretory pathway Ca 2+ /Mn 2+ -transport ATPase (SPCA1a)
Published in The Journal of biological chemistry (28-04-2017)“…The Golgi/secretory pathway Ca /Mn -transport ATPase (SPCA1a) is implicated in breast cancer and Hailey-Hailey disease. Here, we purified recombinant human…”
Get full text
Journal Article