Search Results - "Sluijter, Joost P G"

Circadian rhythms and the molecular clock in cardiovascular biology and disease by Crnko, Sandra, Du Pré, Bastiaan C., Sluijter, Joost P. G., Van Laake, Linda W.

“…The Earth turns on its axis every 24 h; almost all life on the planet has a mechanism — circadian rhythmicity — to anticipate the daily changes caused by this…”
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METTL14 is required for exercise-induced cardiac hypertrophy and protects against myocardial ischemia-reperfusion injury by Wang, Lijun, Wang, Jiaqi, Yu, Pujiao, Feng, Jingyi, Xu, Gui-e, Zhao, Xuan, Wang, Tianhui, Lehmann, H. Immo, Li, Guoping, Sluijter, Joost P. G., Xiao, Junjie

“…RNA m 6 A modification is the most widely distributed RNA methylation and is closely related to various pathophysiological processes. Although the benefit of…”
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Cathelicidin-related antimicrobial peptide protects against myocardial ischemia/reperfusion injury by Bei, Yihua, Pan, Li-Long, Zhou, Qiulian, Zhao, Cuimei, Xie, Yuan, Wu, Chengfei, Meng, Xiangmin, Gu, Huanyu, Xu, Jiahong, Zhou, Lei, Sluijter, Joost P G, Das, Saumya, Agerberth, Birgitta, Sun, Jia, Xiao, Junjie

“…Cathelicidins are a major group of natural antimicrobial peptides which play essential roles in regulating host defense and immunity. In addition to the…”
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MicroRNA-100 Regulates Neovascularization by Suppression of Mammalian Target of Rapamycin in Endothelial and Vascular Smooth Muscle Cells by GRUNDMANN, Sebastian, HANS, Felix P, MOSER, Martin, KINNIRY, Sheena, HEINKE, Jennifer, HELBING, Thomas, BLUHM, Franziska, SLUIJTER, Joost P. G, HOEFER, Imo, PASTERKAMP, Gerard, BODE, Christoph

“…The adaptive growth of blood vessels is an important protective mechanism in cardiovascular disease. However, the underlying regulatory mechanisms of this…”
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A Fast pH-Switchable and Self-Healing Supramolecular Hydrogel Carrier for Guided, Local Catheter Injection in the Infarcted Myocardium by Bastings, Maartje M. C., Koudstaal, Stefan, Kieltyka, Roxanne E., Nakano, Yoko, Pape, A. C. H., Feyen, Dries A. M., van Slochteren, Frebus J., Doevendans, Pieter A., Sluijter, Joost P. G., Meijer, E. W., Chamuleau, Steven A. J., Dankers, Patricia Y. W.

“…Minimally invasive intervention strategies after myocardial infarction use state‐of‐the‐art catheter systems that are able to combine mapping of the infarcted…”
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Exosomes from Cardiomyocyte Progenitor Cells and Mesenchymal Stem Cells Stimulate Angiogenesis Via EMMPRIN by Vrijsen, Krijn R., Maring, Janita A., Chamuleau, Steven A. J., Verhage, Vera, Mol, Emma A., Deddens, Janine C., Metz, Corina H. G., Lodder, Kirsten, van Eeuwijk, Esther C. M., van Dommelen, Susan M., Doevendans, Pieter A., Smits, Anke M., Goumans, Marie-José, Sluijter, Joost P. G.

“…To date, cellular transplantation therapy has not yet fulfilled its high expectations for cardiac repair. A major limiting factor is lack of long‐term…”
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Potential of mesenchymal- and cardiac progenitor cells for therapeutic targeting of B-cells and antibody responses in end-stage heart failure by van den Hoogen, Patricia, de Jager, Saskia C A, Mol, Emma A, Schoneveld, Arjan S, Huibers, Manon M H, Vink, Aryan, Doevendans, Pieter A, Laman, Jon D, Sluijter, Joost P G

“…Upon myocardial damage, the release of cardiac proteins induces a strong antibody-mediated immune response, which can lead to adverse cardiac remodeling and…”
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Small molecule-mediated rapid maturation of human induced pluripotent stem cell-derived cardiomyocytes by Chirico, Nino, Kessler, Elise L, Maas, Renée G C, Fang, Juntao, Qin, Jiabin, Dokter, Inge, Daniels, Mark, Šarić, Tomo, Neef, Klaus, Buikema, Jan-Willem, Lei, Zhiyong, Doevendans, Pieter A, Sluijter, Joost P G, van Mil, Alain

“…Human induced pluripotent stem cell (iPSC)-derived cardiomyocytes (iPSC-CMs) do not display all hallmarks of mature primary cardiomyocytes, especially the…”
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Generation and characterization of novel human induced pluripotent stem cell (iPSC) lines originating from five asymptomatic individuals carrying the PLN-R14del pathogenic variant and a non-carrier relative by Balducci, Valentina, Scardigli, Francesco, Harakalova, Magdalena, Peter. van Tintelen, J., Doevendans, Pieter A., Costa, Kevin D., Turnbull, Irene C., P. G. Sluijter, Joost, Stillitano, Francesca

“…The rare genetic alteration PLN-c.(40_42delAGA), leading to the deletion of arginine 14 (p.R14del) in phospholamban, is associated with dilated and…”
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Vitamin C facilitates direct cardiac reprogramming by inhibiting reactive oxygen species by Fang, Juntao, Yang, Qiangbing, Maas, Renée G C, Buono, Michele, Meijlink, Bram, Lotgerink Bruinenberg, Dyonne, Benavente, Ernest Diez, Mokry, Michal, van Mil, Alain, Qian, Li, Goumans, Marie-José, Schiffelers, Raymond, Lei, Zhiyong, Sluijter, Joost P G

“…After myocardial infarction, the lost myocardium is replaced by fibrotic tissue, eventually progressively leading to myocardial dysfunction. Direct…”
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Extracellular Vesicle-Associated Proteins in Tissue Repair by Roefs, Marieke T., Sluijter, Joost P.G., Vader, Pieter

“…The administration of (stem) cell-derived extracellular vesicles (EVs) promotes tissue repair through management of different inflammatory, proliferative and…”
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Drug Delivery with Extracellular Vesicles: From Imagination to Innovation by de Jong, Olivier G, Kooijmans, Sander A. A, Murphy, Daniel E, Jiang, Linglei, Evers, Martijn J. W, Sluijter, Joost P. G, Vader, Pieter, Schiffelers, Raymond M

“…Conspectus Extracellular vesicles are nanoparticles produced by cells. They are composed of cellular membrane with associated membrane proteins that surrounds…”
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Presence of Cx43 in extracellular vesicles reduces the cardiotoxicity of the anti-tumour therapeutic approach with doxorubicin by Martins-Marques, Tania, Pinho, Maria Joao, Zuzarte, Monica, Oliveira, Carla, Pereira, Paulo, Sluijter, Joost P. G., Gomes, Celia, Girao, Henrique

“…Extracellular vesicles (EVs) are major conveyors of biological information, mediating local and systemic cell-to-cell communication under physiological and…”
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Cardiac fibroblasts and mechanosensation in heart development, health and disease by Pesce, Maurizio, Duda, Georg N., Forte, Giancarlo, Girao, Henrique, Raya, Angel, Roca-Cusachs, Pere, Sluijter, Joost P. G., Tschöpe, Carsten, Van Linthout, Sophie

“…The term ‘mechanosensation’ describes the capacity of cells to translate mechanical stimuli into the coordinated regulation of intracellular signals, cellular…”
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Scalable purification of extracellular vesicles with high yield and purity using multimodal flowthrough chromatography by Bonner, Scott E., Wakker, Simonides I., Phillips, William, Willms, Eduard, Sluijter, Joost P. G., Hill, Andrew F., Wood, Matthew J. A., Vader, Pieter

“…Extracellular vesicles (EVs) are cell derived membranous nanoparticles. EVs are important mediators of cell–cell communication via the transfer of bioactive…”
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Extracellular vesicle‐mediated protein delivery to the liver by Ilahibaks, Nazma F., Roefs, Marieke T., Brans, Maike A. D., Blok, Christian Snijders, Jager, Saskia C. A., Schiffelers, Raymond M., Vader, Pieter, Lei, Zhiyong, Sluijter, Joost P. G.

“…Extracellular vesicles (EVs) are nanoscale particles that facilitate intercellular communication. They are regarded as a promising natural drug delivery system…”
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Inhibition of miR-25 improves cardiac contractility in the failing heart by Wahlquist, Christine, Jeong, Dongtak, Rojas-Muñoz, Agustin, Kho, Changwon, Lee, Ahyoung, Mitsuyama, Shinichi, van Mil, Alain, Jin Park, Woo, Sluijter, Joost P. G., Doevendans, Pieter A. F., Hajjar, Roger J., Mercola, Mark

“…Reduced activity of the calcium-transporting ATPase SERCA2a is a hallmark of heart failure; here, microRNAs that downregulate SERCA2a function are identified,…”
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NLRP3-Inflammasome Inhibition with IZD334 Does Not Reduce Cardiac Damage in a Pig Model of Myocardial Infarction by Silvis, Max J M, Demkes, Evelyne J, Timmers, Leo, Arslan, Fatih, de Jager, Saskia C A, Sluijter, Joost P G, Mosterd, Arend, de Kleijn, Dominique P V, Bosch, Lena, van Hout, Gerardus P J

“…NLRP3-inflammasome-mediated signaling is thought to significantly contribute to the extent of myocardial damage after myocardial infarction (MI). The purpose…”
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Functional siRNA Delivery by Extracellular Vesicle–Liposome Hybrid Nanoparticles by Evers, Martijn J. W., Wakker, Simonides I., Groot, Ellis M., Jong, Olivier G., Gitz‐François, Jerney J. J., Seinen, Cor S., Sluijter, Joost P. G., Schiffelers, Raymond M., Vader, Pieter

“…The therapeutic use of RNA interference is limited by the inability of siRNA molecules to reach their site of action, the cytosol of target cells. Lipid…”
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Inhibition of RIP1-dependent necrosis prevents adverse cardiac remodeling after myocardial ischemia–reperfusion in vivo by Oerlemans, Martinus I. F. J., Liu, Jia, Arslan, Fatih, den Ouden, Krista, van Middelaar, Ben J., Doevendans, Pieter A., Sluijter, Joost P. G.

“…Accumulating evidence indicatesthat programmed necrosis plays a critical role in cell death during ischemia–reperfusion. Necrostatin-1 (Nec-1), a small…”
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