Search Results - "Slot, L Bruins"

Signal transduction and functional selectivity of F15599, a preferential post‐synaptic 5‐HT1A receptor agonist by Newman‐Tancredi, A, Martel, J‐C, Assié, M‐B, Buritova, J, Lauressergues, E, Cosi, C, Heusler, P, Bruins Slot, L, Colpaert, FC, Vacher, B, Cussac, D

“…Background and purpose:  Activation of post‐synaptic 5‐HT1A receptors may provide enhanced therapy against depression. We describe the signal transduction…”
Get full text

Opiate self-administration as a measure of chronic nociceptive pain in arthritic rats by Colpaert, F.C, Tarayre, J.P, Alliaga, M, Bruins Slot, L.A, Attal, N, Koek, W

“…The study examined the validity of oral fentanyl self-administration (FSA) as a measure of the chronic nociceptive pain that develops in rats with adjuvant…”
Get full text

Study of the addictive potential of modafinil in naive and cocaine-experienced rats by DEROCHE-GAMONET, V, DARNAUDERY, M, BRUINS-SLOT, L, PIAT, F, LE MOAL, M, PIAZZA, P. V

“…Modafinil is a drug that promotes wakefulness and, as such, is used to treat hypersomnia and narcolepsy. Preclinical and clinical studies suggest that…”
Get full text

Opiate States of Memory: Receptor Mechanisms by Slot, L. A. Bruins, Colpaert, F. C

“…The present studies characterized the receptor mechanisms of morphine-induced states of memory. Morphine (5 mg/kg) produced a state in which rats could learn…”
Get full text

F15063, a compound with D2/D3 antagonist, 5‐HT1A agonist and D4 partial agonist properties: (III) Activity in models of cognition and negative symptoms by Depoortère, R, Auclair, A L, Bardin, L, Slot, L Bruins, Kleven, M S, Colpaert, F, Vacher, B, Newman‐Tancredi, A

“…Background and purpose: The D2/D3 receptor antagonist, D4 receptor partial agonist, and high efficacy 5‐HT1A receptor agonist F15063 was shown to be highly…”
Get full text

Signal transduction and functional selectivity of F15599, a preferential post‐synaptic 5‐HT 1A receptor agonist by Newman‐Tancredi, A, Martel, J‐C, Assié, M‐B, Buritova, J, Lauressergues, E, Cosi, C, Heusler, P, Bruins Slot, L, Colpaert, FC, Vacher, B, Cussac, D

“…Background and purpose:  Activation of post‐synaptic 5‐HT 1A receptors may provide enhanced therapy against depression. We describe the signal transduction…”
Get full text

F15063, a potential antipsychotic with D2/D3 antagonist, 5‐HT1A agonist and D4 partial agonist properties: (I) in vitro receptor affinity and efficacy profile by Newman‐Tancredi, A, Assié, M‐B, Martel, J‐C, Cosi, C, Slot, L Bruins, Palmier, C, Rauly‐Lestienne, I, Colpaert, F, Vacher, B, Cussac, D

“…Background and purpose: Combining 5‐HT1A receptor activation with dopamine D2/D3 receptor blockade should improve negative symptoms and cognitive deficits in…”
Get full text

F15063, a compound with D 2 /D 3 antagonist, 5‐HT 1A agonist and D 4 partial agonist properties: (III) Activity in models of cognition and negative symptoms by Depoortère, R, Auclair, A L, Bardin, L, Slot, L Bruins, Kleven, M S, Colpaert, F, Vacher, B, Newman‐Tancredi, A

“…Background and purpose: The D 2 /D 3 receptor antagonist, D 4 receptor partial agonist, and high efficacy 5‐HT 1A receptor agonist F15063 was shown to be…”
Get full text

F15063, a potential antipsychotic with D 2 /D 3 antagonist, 5‐HT 1A agonist and D 4 partial agonist properties: (I) in vitro receptor affinity and efficacy profile by Newman‐Tancredi, A, Assié, M‐B, Martel, J‐C, Cosi, C, Slot, L Bruins, Palmier, C, Rauly‐Lestienne, I, Colpaert, F, Vacher, B, Cussac, D

“…Background and purpose: Combining 5‐HT 1A receptor activation with dopamine D 2 /D 3 receptor blockade should improve negative symptoms and cognitive deficits…”
Get full text

Lack of Association between Anorexia Nervosa and D3 Dopamine Receptor Gene by Bruins-Slot, Lisbeth, Gorwood, Philip, Bouvard, Manuel, Blot, Phillipe, Adès, Jean, Feingold, Josué, Schwartz, Jean-Charles, Mouren-Siméoni, Marie-Christine

“…Background: Evidence from family and twin studies suggests a genetic contribution to the etiology of anorexia nervosa. Different genes could contribute to the…”
Get full text

Recall Rendered Dependent on an Opiate State by Slot, L. A. Bruins, Colpaert, F. C

“…Remembering may require that the organism be in a state that is similar to that in which the event was initially experienced (state dependence [StD]). We…”
Get full text

Experimental conditions for the continuous subcutaneous infusion of four central analgesics in rats by Bruins Slot, L.A, Tarayre, J.-P, Koek, W, Ribet, J.-P, Colpaert, F.C

“…For the analysis of pharmacotherapeutic regimens for chronic pain in animals, it is important to establish delivery methods in which analgesics can be…”
Get full text

Sign-reversal during Persistent Activation in μ -Opioid Signal Transduction by BRUINS SLOT, L.A., PAUWELS, P.J., COLPAERT, F.C.

“…A concept of signal transduction in biological systems specifies that any instantaneous input is appreciated by its departure from the moving average of past…”
Get full text

Neuroactive steroids and the constraint of memory by Slot, L. A. Bruins, Piazza, P. V., Colpaert, F. C.

“…Different normo‐ and pathophysiological conditions are associated with large variations in plasma and brain concentrations of neuroactive steroids. In an…”
Get full text

5-HT2A gene promoter polymorphism as a modifying rather than a vulnerability factor in anorexia nervosa by KIPMAN, A, BRUINS-SLOT, L, BONI, C, HANOUN, N, ADES, J, BLOT, P, HAMON, M, MOUREN-SIMEONI, M.-C, GORWOOD, P

Get full text

Evidence that mnesic states govern normal and disordered memory by Colpaert, F.C, Koek, W, Bruins Slot, L.A

“…Although it is recognized that retrieval may be state-dependent, only recently has a paradigm been identified that allows state-dependence in rats to be…”
Get full text

A persistent opioid-addiction state of memory by Bruins Slot, L.A, Colpaert, F.C

“…We determined whether tolerance develops to a morphine-induced state of memory. Rats were injected with 5 mg/kg of morphine and trained to complete a FR-10…”
Get full text

Memory of an operant response and of depressed mood retained in activation states of 5-HT(1A) receptors: evidence from rodent models by Colpaert, F C, Bruins Slot, L A, Koek, W, Dupuis, D S

“…Three series of studies were conducted to specify the role of 5-HT(1A) receptors in memory; using selective ligands that differentially activate 5-HT(1A)…”
Get full text

5-HT 2A gene promoter polymorphism as a modifying rather than a vulnerability factor in anorexia nervosa by Kipman, A, Bruins-Slot, L, Boni, C, Hanoun, N, Adès, J, Blot, P, Hamon, M, Mouren-Siméoni, M.C, Gorwood, P

“…The A allele of the 5-HT 2A gene (–1438A/G polymorphism) has been associated with anorexia nervosa in four studies, but not in three others. One possibility to…”
Get full text

Ethanol state dependence involving a lever press response requirement in rats by Bruins Slot, L A, Koek, W, Colpaert, F C

“…Previous studies have found that the timely completion of an FR10 schedule of food-rewarded lever pressing in rats demonstrates state dependence in…”
Get more information