Search Results - "Slosberg, E."

The Signature Program: Bringing the Protocol to the Patient by Kang, BP, Slosberg, E, Snodgrass, S, Lebedinsky, C, Berry, DA, Corless, CL, Stein, S, Salvado, A

“…Early‐phase clinical development in oncology has evolved dramatically with the deciphering of the human genome in 2004. Genomic analysis and the tools…”
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Phase I study of the AXL inhibitor DS-1205c in combination with osimertinib in subjects with metastatic or unresectable EGFR-mutant NSCLC by Planchard, D., Janne, P.A., Yu, H.A., Moro-Sibilot, D., Goldberg, T., Gu, X., Li, J., McGill, J., Yu, C., Slosberg, E.

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Enhanced function of immuno-isolated islets in diabetes therapy by co-encapsulation with an anti-inflammatory drug by Dang, Tram T, Thai, Anh V, Cohen, Joshua, Slosberg, Jeremy E, Siniakowicz, Karolina, Doloff, Joshua C, Ma, Minglin, Hollister-Lock, Jennifer, Tang, Katherine M, Gu, Zhen, Cheng, Hao, Weir, Gordon C, Langer, Robert, Anderson, Daniel G

“…Abstract Immuno-isolation of islets has the potential to enable the replacement of pancreatic function in diabetic patients. However, host response to the…”
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Increased susceptibility to carcinogen-induced mammary tumors in MMTV-Cdc25B transgenic mice by YAO YAO, SLOSBERG, E. D, LEI WANG, HIBSHOOSH, H, ZHANG, Y.-J, XING, W.-Q, SANTELLA, R. M, WEINSTEIN, I. B

“…Cdc25 phosphatases activate cyclin-dependent kinases (Cdks) by dephosphorylating critical phospho-tyrosine and phospho-threonine residues on these proteins…”
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Endoscopic band ligation for actively bleeding Dieulafoy's lesions by Gerson, L B, Yap, E, Slosberg, E, Soetikno, R M

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Treatment of Type 2 Diabetes by Adenoviral-Mediated Overexpression of the Glucokinase Regulatory Protein by SLOSBERG, Eric D, DESAI, Urvi J, FANELLI, Barbara, DENNY, Irene St, CONNELLY, Sheila, KALEKO, Michael, BOETTCHER, Brian R, CAPLAN, Shari L

“…Treatment of Type 2 Diabetes by Adenoviral-Mediated Overexpression of the Glucokinase Regulatory Protein Eric D. Slosberg 1 , Urvi J. Desai 2 , Barbara Fanelli…”
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Chemo-radiotherapy for localized pancreatic cancer: increased dose intensity and reduced acute toxicity with concomitant radiotherapy and protracted venous infusion 5-fluorouracil by Poen, J C, Collins, H L, Niederhuber, J E, Oberhelman, H A, Vierra, M A, Bastidas, A J, Young, H S, Slosberg, E A, Jeffrey, B R, Longacre, T A, Fisher, G A, Goffinet, D R

“…Although concomitant radiation therapy (RT) and bolus 5-Fluorouracil (5-FU) have been shown to improve survival in locally confined pancreatic cancer, most…”
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Differential subtraction chain, a method for identifying differences in genomic DNA and mRNA by Luo, Jian-Hua, Puc, Janusz A., Wright, Thomas C., Parsons, Ramon, Slosberg, Eric D., Yao, Yao, Bruce, Jeffrey N., Becich, Michael J.

“…Identifying the genetic differences between two organisms or cell types has been a major goal in modern biomedical research. Recently, we developed a novel…”
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Phenotypic Correction of Diabetic Mice by Adenovirus-Mediated Glucokinase Expression by DESAI, Urvi J, SLOSBERG, Eric D, BOETTCHER, Brian R, CAPLAN, Shari L, FANELLI, Barbara, STEPHAN, Zouhair, GUNTHER, Vicky J, KALEKO, Michael, CONNELLY, Sheila

“…Phenotypic Correction of Diabetic Mice by Adenovirus-Mediated Glucokinase Expression Urvi J. Desai 1 , Eric D. Slosberg 2 , Brian R. Boettcher 2 , Shari L…”
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Characterization of PKCI and Comparative Studies with FHIT, Related Members of the HIT Protein Family by Klein, Michael G., Yao, Yao, Slosberg, Eric D., Lima, Christopher D., Doki, Yuichiro, Weinstein, I.Bernard

“…We previously described the isolation of a human cDNA that encodes a protein termed protein kinase C inhibitor (hPKCI). We elucidated the three-dimensional…”
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570P A first-in-human phase I study of the AXL inhibitor DS-1205c in combination with gefitinib in subjects with EGFR-mutant NSCLC by Nishio, M., Okamoto, I., Murakami, H., Horinouchi, H., Toyozawa, R., Takeda, M., Uno, M., Crawford, N., Jimbo, T., Ishigami, M., Takayama, G., Nakayama, S., Ohwada, S., Slosberg, E., Goto, K.

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1506TiPPhase I study of the AXL inhibitor DS-1205c in combination with osimertinib in subjects with metastatic or unresectable EGFR-mutant NSCLC by Planchard, D, Janne, P A, Yu, H A, Moro-Sibilot, D, Goldberg, T, Gu, X, Li, J, McGill, J, Yu, C, Slosberg, E

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The α isoform of protein kinase C mediates phorbol ester-induced growth inhibition and p21cip1 induction in HC11 mammary epithelial cells by SLOSBERG, E. D, KLEIN, M. G, YAO YAO, HAN, E. K.-H, SCHIEREN, I, WEINSTEIN, I. B

“…To clarify the roles of specific isoforms of PKC in regulating growth and cell cycle progression of the HC11 mammary epithelial cell line, we investigated the…”
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Sclerotherapy versus banding in the treatment of variceal bleeding by Slosberg, E A, Keeffe, E B

“…Endoscopic sclerotherapy has been the mainstay in the management of esophageal variceal bleeding to control acute bleeding and decrease recurrent bleeding…”
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The successful use of telemedicine in acute variceal hemorrhage by Ahmed, A, Slosberg, E, Prasad, P, Keeffe, E B, Imperial, J C

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Chondrocyte cluster formation in agarose cultures as a functional assay to identify genes expressed in osteoarthritis by Quintavalla, Joseph, Kumar, Chandrika, Daouti, Sherif, Slosberg, Eric, Uziel-Fusi, Susan

“…Understanding altered gene expression in osteoarthritic cartilage can lead to new targets for drug intervention. We established a functional assay based on…”
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The Importance of Disclaimers: Distinction Between Optimal Care and Standard of Care by Slosberg, Eric Joel, Smith, C. Giles, Jr, Esquir

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Congenital nephrotic syndrome detected by hypothyroid screening by Finnegan, J T, Slosberg, E J, Postellon, D C, Primack, W A

“…An infant was evaluated for a low thyroxine value, detected on routine neonatal screening for congenital hypothyroidism. She was found to have the congenital…”
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Interactions of retinol with binding proteins: Studies with retinol-binding protein and with transthyretin by Noy, Noa, Slosberg, Eric, Scarlata, Suzanne

“…The interactions within the molecular complex in which retinol circulates in blood were studied. To monitor binding between retinol-binding protein (RBP) and…”
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Induction of differentiation in mouse erythroleukaemia cells by the action of papain at the cell surface by Slosberg, E A, Scher, B M, Scher, W, Josephson, S, Waxman, S

“…The addition of one of several proteases to cultures of mouse erythroleukaemia (MEL) or human K-562 leukaemia cells can induce a substantial portion of the…”
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