Search Results - "Sloot, Yvette J. E."
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Effect of PTEN inactivating germline mutations on innate immune cell function and thyroid cancer-induced macrophages in patients with PTEN hamartoma tumor syndrome
Published in Oncogene (01-05-2019)“…PTEN hamartoma tumor syndrome (PHTS) is caused by inactivating germline PTEN mutations with subsequent activation of Akt-mTOR signaling, leading to an…”
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The Influence of Energy Depletion by Metformin or Hypocaloric Diet on Thyroid Iodine Uptake in Healthy Volunteers: a Randomized Trial
Published in Scientific reports (01-04-2019)“…Sufficient thyroid iodine uptake is needed to ensure effective radioactive iodine (RAI) treatment, which is mediated by the sodium-iodide symporter (NIS)…”
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Divergent Metastatic Patterns Between Subtypes of Thyroid Carcinoma Results From the Nationwide Dutch Pathology Registry
Published in The journal of clinical endocrinology and metabolism (01-03-2020)“…Abstract Background Metastatic disease is the main cause of cancer-related mortality in thyroid carcinoma (TC) patients. Clinical studies have suggested…”
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Thyrotrophin and thyroxine support immune homeostasis in humans
Published in Immunology (01-06-2021)“…Summary The endocrine and the immune systems interact by sharing receptors for hormones and cytokines, cross‐control and feedback mechanisms. To date, no…”
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Insights into the role of IL-32 in cancer
Published in Seminars in immunology (01-08-2018)“…•IL-32 has emerged as a new player with complex roles in cancer and cancer-related inflammation, which are isoform dependent.•IL-32 expression is increased in…”
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Interplay between thyroid cancer cells and macrophages: effects on IL-32 mediated cell death and thyroid cancer cell migration
Published in Cellular oncology (Dordrecht) (01-10-2019)“…Purpose Interleukin 32 (IL-32) is a pro-inflammatory cytokine of which different isoforms have been identified. Recently, IL-32 has been shown to act as a…”
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