Search Results - "Slonimskaya, E."
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Somatic-stem transition of tumor cells is a key link in the metastasis
Published in Annals of oncology (01-10-2018)Get full text
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Breast tumour cell subpopulations with expression of the MYC and OCT4 proteins
Published in Journal of molecular histology (01-12-2020)“…The MYC and OCT4 genes are known factors associated with maintaining pluripotency and are linked with a more aggressive course, progression, and resistance to…”
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Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) Contributes to Tamoxifen Resistance in Estrogen-Positive Breast Cancer Patients
Published in Molecular biology (New York) (2021)“…Crosstalk between the estrogen receptors and the receptor tyrosine kinases, including vascular endothelial growth factor receptor type II (VEGFR2), is a key…”
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Genome-wide association study of loss of heterozygosity and metastasis-free survival in breast cancer patients
Published in Experimental oncology (01-07-2017)“…One of the factors providing the diversity and heterogeneity of malignant tumors, particularly breast cancer, are genetic variations, due to gene polymorphism,…”
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Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) Contributes to Tamoxifen Resistance in Estrogen-Positive Breast Cancer Patients
Published in Molekuliarnaia biologiia (01-01-2021)“…Crosstalk between the estrogen receptors and the receptor tyrosine kinases, including vascular endothelial growth factor receptor type II (VEGFR2), is a key…”
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VHL Expression in Kidney Cancer: Relation to Metastasis Development, Transcription and Growth Factors and Component of Akt/m-TOR Signaling Pathway
Published in Bulletin of experimental biology and medicine (01-09-2019)“…Von Hippel—Lindau protein (VHL) is associated with the development and progression of kidney cancer. An increase in VHL expression was found in patients with…”
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Transcription factors NF-kB, HIF-1, HIF-2, growth factor VEGF, VEGFR2 and carboanhydrase IX mRNA and protein level in the development of kidney cancer metastasis
Published in Molecular biology (New York) (01-03-2017)“…Here, we have investigated the participation of nuclear factors NF-kB, HIF-1 and HIF-2, VEGF, VEGFR2, and carboanhydrase IX in clear-cell renal cancer. We have…”
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Clinicopathological features of nonspecific invasive breast cancer according to its molecular subtypes
Published in Experimental oncology (01-06-2016)“…The aim of the present study was to investigate the clinical and morphological features of nonspecific invasive breast cancer according to its molecular…”
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P6
Published in European journal of cancer supplements (01-11-2015)“…Background Tamoxifen, a selective estrogen receptor modulator, remains a standard of endocrine therapy for estrogen receptor alpha (ER α ) positive breast…”
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P13
Published in European journal of cancer supplements (01-11-2015)“…Background The tumor microenvironment plays an important role in the progression of cancer and may be regulated by proteolysis, including the proteasomes. The…”
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P77
Published in European journal of cancer supplements (01-11-2015)“…Background There are numerous evidences suggesting that tumor evolution follows the laws of Darwinian evolution, whereby individual tumor cell clones have…”
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Transcription factors NF-kB, HIF-1, HIF-2, growth factor VEGF, VEGFR2 and carboanhydrase IX mRNA and protein level in the development of kidney cancer metastasis
Published in Molekuliarnaia biologiia (01-03-2017)“…Here, we have investigated the participation of nuclear factors NF-kB, HIF-1 and HIF-2, VEGF, VEGFR2, and carboanhydrase IX in clear-cell renal cancer. We have…”
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TRIM16 transcription factor in prostate cancer
Published in Bi͡u︡lletenʹ Sibirskoĭ medit͡s︡iny (29-09-2018)“…The aim of this investigation was to reveal the expression TRIM16, ERα, ERβ and AR in prostate cancer tissues compared to benign hyperplasia and clinical and…”
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Changes in the Activity of Proteasomes and Calpains in Metastases of Human Lung Cancer and Breast Cancer
Published in Bulletin of experimental biology and medicine (01-08-2017)“…In patients with breast cancer and lung cancer, chymotrypsin-like and caspase-like activities of proteasomes and total activity of calpains in the primary…”
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Effect of Target Therapy on the Content of Transcription and Growth Factors, Protein Kinase TOR, and Activity of Intracellular Proteases in Patients with Metastatic Renal Cell Carcinoma
Published in Bulletin of experimental biology and medicine (01-04-2016)“…We analyzed the dynamics of the expression of transcription factors, VEGF and its receptor VEGFR2, serine-threonine protein kinase mTOR and activity of…”
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P78
Published in European journal of cancer supplements (01-11-2015)“…Background Breast cancer, particularly invasive carcinoma of no special type (IC NST), demonstrates considerable intratumor morphological heterogeneity. Five…”
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A14
Published in European journal of cancer supplements (01-11-2015)“…Background Intratumoral heterogeneity contributes significantly to the effectiveness of cancer treatment and outcome (Ng C.K., Pemberton H.N., Reis-Filho J.S.,…”
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Chymotrypsin-like activity and subunit composition of proteasomes in human cancers
Published in Molecular biology (New York) (01-05-2014)“…The activity of the proteasome, a polyfunctional enzymatic complex, is known to undergo changes during cancer development. This phenomenon is probably caused…”
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Aberrations of the number of copies (CNA) in the genome of luminal B breast tumor
Published in Bi͡u︡lletenʹ Sibirskoĭ medit͡s︡iny (07-10-2020)“…Aim. To describe the CNA (Copy Number Aberration) landscape of luminal B breast tumor before treatment.Materials and methods. The study included 100 patients…”
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