Search Results - "Slominsky, Petr A."

Genetics Factors in Major Depression Disease by Shadrina, Maria, Bondarenko, Elena A, Slominsky, Petr A

“…Depressive disorders (DDs) are one of the most widespread forms of psychiatric pathology. According to the World Health Organization, about 350 million people…”
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Genetic Architecture of Parkinson’s Disease by Shadrina, Maria I., Slominsky, Petr A.

“…Year 2022 marks 25 years since the first mutation in familial autosomal dominant Parkinson’s disease was identified. Over the years, our understanding of the…”
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Major Depression: One Brain, One Disease, One Set of Intertwined Processes by Filatova, Elena V., Shadrina, Maria I., Slominsky, Petr A.

“…Major depressive disorder (MDD) is a heterogeneous disease affecting one out of five individuals and is the leading cause of disability worldwide. Presently,…”
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Whole Transcriptome Analysis of Substantia Nigra in Mice with MPTP-Induced Parkinsonism Bearing Defective Glucocerebrosidase Activity by Usenko, Tatiana, Bezrukova, Anastasia, Rudenok, Margarita M, Basharova, Katerina, Shadrina, Maria I, Slominsky, Petr A, Zakharova, Ekaterina, Pchelina, Sofya

“…Mutations in the gene represent the major genetic risk factor for Parkinson's disease (PD). The lysosomal enzyme beta-glucocerebrosidase (GCase) encoded by the…”
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Effects of Age and MPTP-Induced Parkinson's Disease on the Expression of Genes Associated with the Regulation of the Sleep-Wake Cycle in Mice by Semenova, Ekaterina I, Rudenok, Margarita M, Rybolovlev, Ivan N, Shulskaya, Marina V, Lukashevich, Maria V, Partevian, Suzanna A, Budko, Alexander I, Nesterov, Maxim S, Abaimov, Denis A, Slominsky, Petr A, Shadrina, Maria I, Alieva, Anelya Kh

“…Parkinson's disease (PD) is characterized by a long prodromal period, during which patients often have sleep disturbances. The histaminergic system and…”
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Maternal Methyl-Enriched Diet Increases DNMT1, HCN1, and TH Gene Expression and Suppresses Absence Seizures and Comorbid Depression in Offspring of WAG/Rij Rats by Sarkisova, Karine Yu, Fedosova, Ekaterina A, Shatskova, Alla B, Rudenok, Margarita M, Stanishevskaya, Vera A, Slominsky, Petr A

“…The reduced expression of the HCN1 ion channel in the somatosensory cortex (SSC) and mesolimbic dopamine deficiency are thought to be associated with the…”
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Housekeeping Genes for Parkinson’s Disease in Humans and Mice by Alieva, Anelya Kh, Filatova, Elena V., Rudenok, Margarita M., Slominsky, Petr A., Shadrina, Maria I.

“…A critical aspect of real-time PCR is the presence of housekeeping genes (HKGs) as an internal control for the normalization of expression data for genes of…”
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Analysis of LRRN3 , MEF2C , SLC22A , and P2RY12 Gene Expression in the Peripheral Blood of Patients in the Early Stages of Parkinson's Disease by Shulskaya, Marina V, Semenova, Ekaterina I, Rudenok, Margarita M, Partevian, Suzanna A, Lukashevich, Maria V, Karabanov, Alexei V, Fedotova, Ekaterina Yu, Illarioshkin, Sergey N, Slominsky, Petr A, Shadrina, Maria I, Alieva, Anelya Kh

“…Parkinson's disease (PD) is one of the most common human neurodegenerative diseases. Belated diagnoses of PD and late treatment are caused by its elongated…”
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Transcriptome Profiling Reveals Differential Expression of Circadian Behavior Genes in Peripheral Blood of Monozygotic Twins Discordant for Parkinson's Disease by Semenova, Ekaterina I, Vlasov, Ivan N, Partevian, Suzanna A, Rosinskaya, Anna V, Rybolovlev, Ivan N, Slominsky, Petr A, Shadrina, Maria I, Alieva, Anelya Kh

“…Parkinson's disease (PD) is one of the most common neurodegenerative diseases. Investigating individuals with the most identical genetic background is optimal…”
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Expression Analysis of Genes Involved in Transport Processes in Mice with MPTP-Induced Model of Parkinson's Disease by Rudenok, Margarita M, Shadrina, Maria I, Filatova, Elena V, Rybolovlev, Ivan N, Nesterov, Maxim S, Abaimov, Denis A, Ageldinov, Ruslan A, Kolacheva, Anna A, Ugrumov, Michael V, Slominsky, Petr A, Alieva, Anelya Kh

“…Processes of intracellular and extracellular transport play one of the most important roles in the functioning of cells. Changes to transport mechanisms in a…”
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Targeted exome analysis of Russian patients with hypertrophic cardiomyopathy by Filatova, Elena V., Krylova, Natalia S., Vlasov, Ivan N., Maslova, Maria S., Poteshkina, Natalia G., Slominsky, Petr A., Shadrina, Maria I.

“…Background Hypertrophic cardiomyopathy (HCM), described as the presence of hypertrophy of left ventricular, is the most prevalent heritable cardiovascular…”
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Whole-Exome Sequencing in Searching for New Variants Associated With the Development of Parkinson's Disease by Shulskaya, Marina V, Alieva, Anelya Kh, Vlasov, Ivan N, Zyrin, Vladimir V, Fedotova, Ekaterina Yu, Abramycheva, Natalia Yu, Usenko, Tatiana S, Yakimovsky, Andrei F, Emelyanov, Anton K, Pchelina, Sofya N, Illarioshkin, Sergei N, Slominsky, Petr A, Shadrina, Maria I

“…: Parkinson's disease (PD) is a complex disease with its monogenic forms accounting for less than 10% of all cases. Whole-exome sequencing (WES) technology has…”
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Potential Biomarkers of the Earliest Clinical Stages of Parkinson's Disease by Slominsky, Petr A., Illarioshkin, Sergey N., Karabanov, Aleksey V., Filatova, Elena V., Alieva, Anelya Kh, Shadrina, Maria I.

“…Parkinson’s disease (PD) is a widespread neurodegenerative disorder. Despite the intensive studies of this pathology, in general, the picture of the…”
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GSTM1 copy number variation in the context of single nucleotide polymorphisms in the human GSTM cluster by Khrunin, Andrey V, Filippova, Irina N, Aliev, Aydar M, Tupitsina, Tat'yana V, Slominsky, Petr A, Limborska, Svetlana A

“…GSTM1 gene deletion is one of the most known copy number polymorphisms in human genome. It is most likely caused by homologous recombination between the…”
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Analysis of Expression of the GRIPAP1, DLG4, KIF1B, NGFRAP1, and NRF1 Genes in Peripheral Blood of the Patients with Parkinson’s Disease in the Early Clinical Stages by Lukashevich, Maria V., Rudenok, Margarita M., Semenova, Ekaterina I., Partevian, Suzanna A., Karabanov, Alexey V., Fedotova, Elena Yu, Illarioshkin, Sergey N., Slominsky, Petr A., Shadrina, Maria I., Alieva, Anelya Kh

“…Parkinson’s disease (PD) is one of the most common progressive neurodegenerative diseases. An important feature of the disease is its long latent period, which…”
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miRNA expression is highly sensitive to a drug therapy in Parkinson's disease by Alieva, Anelya Kh, Filatova, Elena V, Karabanov, Aleksey V, Illarioshkin, Sergey N, Limborska, Svetlana A, Shadrina, Maria I, Slominsky, Petr A

“…Abstract Background miRNAs may play a role in the pathogenesis of Parkinson's disease. It is necessary to continue the search for new miRNAs that may affect…”
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A new digital approach to SNP encoding for DNA identification by Garafutdinov, Ravil R., Sakhabutdinova, Assol R., Slominsky, Petr A., Aminev, Farit G., Chemeris, Alexey V.

“…•SNP data are digitized as whole 4-bit boxes in the most convenient binary format.•Digitization of SNP data enables creating unique genetic identification…”
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Effective quantitative real-time polymerase chain reaction analysis of the parkin gene (PARK2) exon 1-12 dosage by Shadrina, Maria I, Semenova, Elena V, Slominsky, Petr A, Bagyeva, Gulbahar H, Illarioshkin, Sergei N, Ivanova-Smolenskaia, Irina I, Limborska, Svetlana A

“…One of the causes of Parkinson's disease is mutations in the PARK2 gene. Deletions and duplications of single exons or exon groups account for a large…”
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Transcriptome Profile Changes in Mice with MPTP-Induced Early Stages of Parkinson’s Disease by Alieva, Anelya Kh, Filatova, Elena V., Kolacheva, Anna A., Rudenok, Margarita M., Slominsky, Petr A., Ugrumov, Mikhail V., Shadrina, Maria I.

“…Parkinson’s disease (PD) is one of the most common neurodegenerative diseases. Despite progress in the study of the molecular, genetic, and pathogenic…”
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Analysis of ADORA2A, MTA1, PTGDS, PTGS2, NSF, and HNMT Gene Expression Levels in Peripheral Blood of Patients with Early Stages of Parkinson’s Disease by Semenova, Ekaterina I., Partevian, Suzanna A., Shulskaya, Marina V., Rudenok, Margarita M., Lukashevich, Maria V., Baranova, Nina M., Doronina, Olga B., Doronina, Kseniya S., Rosinskaya, Anna V., Fedotova, Ekaterina Y., Illarioshkin, Sergey N., Slominsky, Petr A., Shadrina, Maria I., Alieva, Anelya Kh

“…Parkinson’s disease (PD) is a common chronic, age-related neurodegenerative disease. This disease is characterized by a long prodromal period. In this context,…”
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