Search Results - "Slobodianuk, Tricia L"

Fibronectin binding to von Willebrand factor occurs via the A1 domain by Keesler, Daniel A., Slobodianuk, Tricia L., Kochelek, Caroline E., Skaer, Chad W., Haberichter, Sandra L., Flood, Veronica H.

“…Collagen interactions with von Willebrand factor (VWF) perform an important role in initiation of hemostasis. We hypothesized that in addition to collagen,…”
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von Willebrand factor binding to myosin assists in coagulation by Flood, Veronica H., Slobodianuk, Tricia L., Keesler, Daniel, Lohmeier, Hannah K., Fahs, Scot, Zhang, Liyun, Simpson, Pippa, Montgomery, Robert R.

“…von Willebrand factor (VWF) binds to platelets and collagen as a means of facilitating coagulation at sites of injury. Recent evidence has shown that myosin…”
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Crucial role for the VWF A1 domain in binding to type IV collagen by Flood, Veronica H., Schlauderaff, Abraham C., Haberichter, Sandra L., Slobodianuk, Tricia L., Jacobi, Paula M., Bellissimo, Daniel B., Christopherson, Pamela A., Friedman, Kenneth D., Gill, Joan Cox, Hoffmann, Raymond G., Montgomery, Robert R.

“…Von Willebrand factor (VWF) contains binding sites for platelets and for vascular collagens to facilitate clot formation at sites of injury. Although previous…”
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von Willebrand factor variant D1472H has no effect in mice with humanized VWF-platelet interactions by Lohmeier, Hannah K., Slobodianuk, Tricia L., Kanaji, Sachiko, Haberichter, Sandra L., Montgomery, Robert R., Flood, Veronica H.

“…The von Willebrand factor ristocetin cofactor activity assay (VWF:RCo) is used for diagnosis of von Willebrand disease (VWD) because of its ability to evaluate…”
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Common VWF sequence variants associated with higher VWF and FVIII are less frequent in subjects diagnosed with type 1 VWD by Flood, Veronica H., Johnsen, Jill M., Kochelek, Caroline, Slobodianuk, Tricia L., Christopherson, Pamela A., Haberichter, Sandra L., Udani, Rupa, Bellissimo, Daniel B., Friedman, Kenneth D., Montgomery, Robert R.

“…Unlabelled Box Genetic variation in the VWF gene is associated with von Willebrand factor (VWF) and factor VIII (FVIII) levels in healthy individuals. We…”
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Critical Extracellular Matrix Proteins Besides Collagen Bind Von Willebrand Factor by Keesler, Daniel A, Kochelek, Caroline E, Slobodianuk, Tricia L, Montgomery, Robert R., Flood, Veronica H

“…Introduction: Vascular endothelial injury exposes blood to many extracellular matrix proteins including collagen. Von Willebrand Factor (VWF) is a coagulation…”
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Von Willebrand Factor Binding to Myosin Assists in Coagulation by Flood, Veronica H, Slobodianuk, Tricia L, Keesler, Daniel A, Lohmeier, Hannah, Fahs, Scot A, Montgomery, Robert R

“…Introduction: Von Willebrand factor (VWF) binds to platelets and collagen as a means of facilitating coagulation at sites of injury. Recent evidence has shown…”
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Prevalence of Low VWF, VWD, and Isolated Collagen Binding Defects in Subjects Undergoing Evaluation for VWD by Haberichter, Sandra L, Slobodianuk, Tricia L, Podd, Andrew, Friedman, Kenneth D, Flood, Veronica H

“…Laboratory testing of von Willebrand disease (VWD) continues to be a complicated and much debated subject. There are multiple tests recommended to assess…”
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Defective collagen binding and increased bleeding in a murine model of von Willebrand disease affecting collagen IV binding by Slobodianuk, T. L., Kochelek, C., Foeckler, J., Kalloway, S., Weiler, H., Flood, V. H.

“…Essentials Defective binding to collagen IV has been seen in von Willebrand factor (VWF) A1 domain variants. We developed a murine model of defective…”
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Bleeding Phenotype Observed in Murine Defect of VWF-Collagen 4 Interactions by Flood, Veronica H, Slobodianuk, Tricia L, Doruelo, Ashley, Adams, Derek, Foeckler, Jamie, Kalloway, Shawn, Weiler, Hartmut, Montgomery, Robert R

“…VWF binding to type 4 collagen has recently been shown to occur via the VWF A1 domain, but the clinical implications of this interaction remain to be…”
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VWF Interaction With Type IV Collagen Is Mediated Through Critical VWF A1 Domain Residues by Flood, Veronica H., Schlauderaff, Abraham C., Jacobi, Paula M., Slobodianuk, Tricia L., Montgomery, Robert R., Haberichter, Sandra L., Program Investigators, The Zimmerman

“…Von Willebrand factor (VWF) plays a key role in coagulation by tethering platelets to injured subendothelium via binding sites for platelet glycoprotein Ib and…”
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