Search Results - "Sloan, Heather"
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Combined IL-21-primed polyclonal CTL plus CTLA4 blockade controls refractory metastatic melanoma in a patient
Published in The Journal of experimental medicine (27-06-2016)“…Adoptive transfer of peripheral blood-derived, melanoma-reactive CD8(+) cytotoxic T lymphocytes (CTLs) alone is generally insufficient to eliminate bulky…”
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T-Cell Therapy Using Interleukin-21-Primed Cytotoxic T-Cell Lymphocytes Combined With Cytotoxic T-Cell Lymphocyte Antigen-4 Blockade Results in Long-Term Cell Persistence and Durable Tumor Regression
Published in Journal of clinical oncology (01-11-2016)“…Purpose Peripheral blood-derived antigen-specific cytotoxic T cells (CTLs) provide a readily available source of effector cells that can be administered with…”
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Margin-to-Margin Seafloor Spreading in the Eastern Gulf of Aden: A 16 Ma-Long History of Deformation and Magmatism from Seismic Reflection, Gravity and Magnetic Data
Published in Frontiers in earth science (Lausanne) (22-07-2021)“…In this paper we present and analyze spreading-parallel seismic transects that image the oceanic crust in the eastern Gulf of Aden, from the Oman to the…”
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Going the distance, going for speed: Honest signaling and the benefits of exercising with an opposite-sex partner
Published in Evolution and human behavior (01-03-2019)Get full text
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Recent off-axis volcanism in the eastern Gulf of Aden: Implications for plume–ridge interaction
Published in Earth and planetary science letters (01-04-2010)“…Evidence of anomalous volcanism is readily observed in the Gulf of Aden, although, much of this oceanic basin remains as yet unmapped. In this paper, we…”
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Regression of metastatic Merkel cell carcinoma following transfer of polyomavirus-specific T cells and therapies capable of re-inducing HLA class-I
Published in Cancer immunology research (01-01-2014)“…Merkel cell carcinoma (MCC) is an aggressive skin cancer that typically requires the persistent expression of Merkel cell polyomavirus (MCPyV) oncoproteins…”
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Responding to a Multiple-Casualty Incident: Room for Improvement
Published in Journal of emergency nursing (01-09-2011)“…One of the challenges of crafting a disaster response is that plans are based on what is most likely to occur. Because disasters and multiple-casualty…”
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IL-15 mediated expansion of rare durable memory T cells following adoptive cellular therapy
Published in Journal for immunotherapy of cancer (01-05-2021)“…BackgroundSynovial sarcoma (SS) and myxoid/round cell liposarcoma (MRCL) are ideal solid tumors for the development of adoptive cellular therapy (ACT)…”
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Overcoming barriers to engaging socio-economically disadvantaged populations in CHD primary prevention: a qualitative study
Published in BMC public health (02-07-2010)“…Preventative medicine has become increasingly important in efforts to reduce the burden of chronic disease in industrialised countries. However, interventions…”
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Greater Somatosensory Afference With Acupuncture Increases Primary Somatosensory Connectivity and Alleviates Fibromyalgia Pain via Insular γ‐Aminobutyric Acid: A Randomized Neuroimaging Trial
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-07-2021)“…Objective Acupuncture is a complex multicomponent treatment that has shown promise in the treatment of fibromyalgia (FM). However, clinical trials have shown…”
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Greater Somatosensory Afference with Acupuncture Increases Primary Somatosensory Connectivity and Alleviates Fibromyalgia Pain via Insular GABA: A Randomized Neuroimaging Trial
Published in Arthritis & rheumatology (Hoboken, N.J.) (31-05-2021)“…Acupuncture is a complex multi-component treatment that has shown promise for the treatment of Fibromyalgia (FM), however, clinical trials have shown mixed…”
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Hydroclimate reconstruction during the last 1000 years inferred from the mineralogical and geochemical composition of a sediment core from Lake-Azuei (Haiti)
Published in Holocene (Sevenoaks) (01-07-2023)“…This study aims to reconstruct the hydro-climatic variations over the last 1000 years in Haiti using mineralogical and geochemical composition of well dated…”
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Identification of ATR-Chk1 pathway inhibitors that selectively target p53-deficient cells without directly suppressing ATR catalytic activity
Published in Cancer research (Chicago, Ill.) (15-12-2014)“…Resistance to DNA-damaging chemotherapy is a barrier to effective treatment that appears to be augmented by p53 functional deficiency in many cancers. In…”
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Phase Ib/II with expansion of patients at the MTD study of olaparib plus weekly (metronomic) carboplatin and paclitaxel in relapsed ovarian cancer patients
Published in Journal of clinical oncology (20-05-2014)“…Abstract only…”
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The Other World Music: Percussion as Purveyor of Cultural Cues in Exotic Lounge Music
Published in College music symposium (01-01-2009)“…Sloan presents an examination of how percussion is used to signify exotic, non-Western cultures in American popular music. In 1957, pianist Martin Denny…”
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Abstract B04: A chemical genetic screen identifies novel ATM/ATR pathway inhibitors that sensitize p53-deficient cells to DNA-damaging agents without affecting ATR kinase catalytic activity
Published in Molecular cancer therapeutics (01-05-2013)“…Abstract An important goal in cancer therapy has been to selectively sensitize cancers to existing drugs that typically work by inducing DNA damage. In…”
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A phase Ib/II trial with expansion of patients at the MTD trial of olaparib plus weekly (metronomic) carboplatin and paclitaxel in relapsed ovarian cancer patients
Published in Journal of clinical oncology (20-05-2015)“…Abstract only…”
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Recent off-axis volcanism in the eastern Gulf of Aden: Implications for plumea"ridge interaction
Published in Earth and planetary science letters (15-04-2010)“…Evidence of anomalous volcanism is readily observed in the Gulf of Aden, although, much of this oceanic basin remains as yet unmapped. In this paper, we…”
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Abstract PR11: Enhanced in vivo persistence and therapeutic activity of combined transferred polyclonal melanoma-reactive CTL generated in presence of IL-21 and anti-CTLA4
Published in Cancer research (Chicago, Ill.) (01-01-2013)“…Abstract Monotherapy with a blocking human anti-CTLA4 mAb achieves disease control in 20-28% of patients (pts), but failure to benefit in the remaining…”
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