Search Results - "Sliwkowski, Mary B."

Ammonium alters N-glycan structures of recombinant TNFR-IgG: Degradative versus biosynthetic mechanisms by Gawlitzek, Martin, Ryll, Thomas, Lofgren, Jim, Sliwkowski, Mary B.

“…The effect of ammonium on the glycosylation pattern of the recombinant immunoadhesin tumor necrosis factor–IgG (TNFR‐IgG) produced by Chinese hamster ovary…”
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Removal of Sialic Acid from a Glycoprotein in CHO Cell Culture Supernatant by Action of an Extracellular CHO Cell Sialidase by Gramer, Michael J, Goochee, Charles F, Chock, Valerie Y, Brousseau, David T, Sliwkowski, Mary B

“…We have directly tested the hypothesis that Chinese hamster ovary (CHO) cell-produced glycoproteins are subject to extracellular degradation by a sialidase…”
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Biochemical characterization of recombinant human nerve growth factor by Schmelzer, C H, Burton, L E, Chan, W P, Martin, E, Gorman, C, Canova-Davis, E, Ling, V T, Sliwkowski, M B, McCray, G, Briggs, J A

“…Recombinant human nerve growth factor (rhNGF) was expressed and secreted by Chinese hamster ovary cells and purified to homogeneity using ion-exchange and…”
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Assessing Genetic Heterogeneity in Production Cell Lines: Detection by Peptide Mapping of a Low Level Tyr to Gln Sequence Variant in a Recombinant Antibody by Harris, Reed J, Murnane, Amy A, Utter, Shannon L, Wagner, Karen L, Cox, Edward T, Polastri, Gian D, Helder, Judith C, Sliwkowski, Mary B

“…A recombinant antibody directed against the human epidermal growth factor receptor-2 extracellular domain was subjected to detailed structural…”
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Incorporation of 15N from ammonium into the N-linked oligosaccharides of an immunoadhesin glycoprotein expressed in Chinese hamster ovary cells by Gawlitzek, Martin, Papac, Damon I., Sliwkowski, Mary B., Ryll, Thomas

“…Elevated ammonium concentrations in the medium of cultivated cells have been shown to increase the intracellular levels of…”
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Isolation and properties of a soluble sialidase from the culture fluid of Chinese hamster ovary cells by Warner, T G, Chang, J, Ferrari, J, Harris, R, McNerney, T, Bennett, G, Burnier, J, Sliwkowski, M B

“…A soluble sialidase that can degrade recombinant glycoproteins expressed in Chinese hamster ovary (CHO) cells has been isolated and purified to near…”
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Purification and characterization of alpha-L-fucosidase from Chinese hamster ovary cell culture supernatant by Gramer, M J, Schaffer, D V, Sliwkowski, M B, Goochee, C F

“…In this study, alpha-L-fucosidase from Chinese hamster ovary (CHO) cell culture supernatant was purified 11 200-fold to apparent homogeneity to assess the rate…”
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