Search Results - "Slimane, M N"

Limited mutational heterogeneity in the LDLR gene in familial hypercholesterolemia in Tunisia by Jelassi, A, Jguirim, I, Najah, M, Abid, A.M, Boughamoura, L, Maatouk, F, Rouis, M, Boileau, C, Rabès, J.P, Slimane, M.N, Varret, M

“…Abstract Familial hypercholesterolemia (FH) is an autosomal dominant disease caused by mutations in the low-density lipoprotein receptor ( LDLR ),…”
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Fh-Souassi: a founder frameshift mutation in exon 10 of the LDL-receptor gene, associated with a mild phenotype in Tunisian families by Slimane, M.N., Lestavel, S., Sun, X.-M., Maatouk, F., Soutar, A.K., Ben Farhat, M.H., Clavey, V., Benlian, P., Hammami, M.

“…Familial hypercholesterolemia (FH) has a higher prevalence in central Tunisia together with a milder clinical expression than in western countries. The…”
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Effect of a splice site mutation in LDLR gene and two variations in PCSK9 gene in Tunisian families with familial hypercholesterolaemia by Jelassi, A, Slimani, A, Jguirim, I, Najah, M, Maatouk, F, Varret, M, Slimane, M N

“…Autosomal dominant hypercholesterolaemia (ADH) is due to defects in the LDL receptor gene (LDLR), in the apolipoprotein B-100 gene (APOB) or in the proprotein…”
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A novel splice site mutation of the LDL receptor gene in a Tunisian hypercholesterolemic family by Jelassi, A., Najah, M., Jguirim, I., Maatouk, F., Lestavel, S., Laroussi, O.S., Rouis, M., Boileau, C., Rabès, J.P., Varret, M., Slimane, M.N.

“…Familial hypercholesterolemia (FH) is an autosomal dominant inherited disease caused by mutations in either the low-density lipoprotein receptor, the…”
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Phenotypic expression of familial hypercholesterolaemia in central and southern Tunisia by Slimane, M N, Pousse, H, Maatoug, F, Hammami, M, Ben Farhat, M H

“…We studied 14 families with familial hypercholesterolaemia (FH) from Central and Southern Tunisia. Twenty-six living homozygotes were identified in these areas…”
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294T/C polymorphism in the PPAR-delta gene is associated with risk of coronary artery disease in normolipidemic Tunisians by Jguirim-Souissi, I, Jelassi, A, Hrira, Y, Najah, M, Slimani, A, Addad, F, Hassine, M, Hamda, K B, Maatouk, F, Rouis, M, Slimane, M N

“…Peroxisome proliferator-activated receptor delta (PPAR-delta) is a transcription factor implicated in metabolism and inflammation. The +294T/C polymorphism in…”
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A011 Matrix metalloproteinase-12 gene regulation by PPAR alpha agonist in human monocyte-derived macrophages by Jguirim-Souissi, I, Billiet, L, Cuaz-Perolin, C, Slimane, M.-N, Rouis, M

“…MMP-12, a macrophage-specific matrix metalloproteinase with large substrate specificity, has been reported to be highly expressed in mice, rabbits and human…”
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Association between variants of lipoprotein lipase and coronary heart disease in a Tunisian population by Jelassi, A, Jguirim, I, Slimani, A, Najah, M, Hamda, K B, Addad, F, Hassine, M, Maatouk, F, Varret, M, Slimane, M N

“…Coronary artery disease (CAD) is a complex multifactorial disease due to the interaction of multiple genes variations and environmental factors. Genetic…”
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CYS127S (FH-Kairouan) and D245N (FH-Tozeur) mutations in the LDL receptor gene in Tunisian families with familial hypercholesterolaemia by Slimane, M N, Lestavel, S, Clavey, V, Maatouk, F, Ben Fahrat, M H, Fruchart, J C, Hammami, M, Benlian, P

“…2 These frequencies are as high as those found in populations with a high degree of inbreeding, such as Afrikaners in South Africa, 3 Christian Lebanese, 4…”
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Anti-Inflammatory and Antiatherogenic Effects of the NLRP3 Inflammasome Inhibitor Arglabin in ApoE2.Ki Mice Fed a High-Fat Diet by Abderrazak, Amna, Couchie, Dominique, Mahmood, Dler Faieeq Darweesh, Elhage, Rima, Vindis, Cécile, Laffargue, Muriel, Matéo, Véronique, Büchele, Berthold, Ayala, Monica Rubio, El Gaafary, Menna, Syrovets, Tatiana, Slimane, Mohamed-Naceur, Friguet, Bertrand, Fulop, Tamas, Simmet, Thomas, El Hadri, Khadija, Rouis, Mustapha

“…BACKGROUND—This study was designed to evaluate the effect of arglabin on the NLRP3 inflammasome inhibition and atherosclerotic lesion in ApoE2Ki mice fed a…”
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294T/C polymorphism in the PPAR- delta gene is associated with risk of coronary artery disease in normoiipidemic Tunisians by Jguirim-Souissi, I, Jelassi, A, Hrira, Y, Najah, M, Slimani, A, Addad, F, Hassine, M, Hamda, K B, Maatouk, F, Rouis, M, Slimane, M N

“…Peroxisome proliferator-activated receptor delta (PPAR- delta ) is a transcription factor implicated in metabolism and inflammation. The +294T/C polymorphism…”
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Infantile cystinosis. A new Tunisian case by Pousse, H, Besbes, A, Slimane, M N, Hammami, M, Ayadi, A, Sfar, M T

“…A case of cystinosis in a three and a half-year-old is reported. Suggestive manifestations included severe rickets, small stature, and complex renal tubule…”
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Familial hypercholesterolemia in Tunisia by Jelassi, A, Jguirim, I, Najah, M, Maatouk, F, Ben Hamda, K, Slimane, M N

“…Familial hypercholesterolemia or autosomal dominant hypercholesterolemia is characterized by raised serum LDL (low density lipoproteins)-cholesterol levels,…”
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Fh-Souassi: a founder frameshift mutation in exon 10 of the LDL-receptor gene, associated with a mild phenotype in Tunisian families: Genetics and atherosclerosis: broadening the horizon by SLIMANE, M. N, LESTAVEL, S, SUN, X.-M, MAATOUK, F, SOUTAR, A. K, BEN FARHAT, M. H, CLAVEY, V, BENLIAN, P, HAMMAMI, M

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Mother-child transmission of hepatitis B virus in the Tunisian Sahel by Soltani, M S, Bchir, A, Slimane, M N, Mtiraoui, A, Ghanem, H, Hammami, M, El May, M, Gueddiche, M N, Ben Ammar, R, Sidhom, M

“…In order to assess the importance of mother-child transmission of the hepatitis B virus (HBV) in the Tunisian Sahel, 81 HBsAg-positive mothers have been…”
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Association entre des variations de la lipoprotéine lipase et la maladie coronarienne dans une population tunisienne by Jelassi, A., Jguirim, I., Slimani, A., Najah, M., Hamda, K.B., Addad, F., Hassine, M., Maatouk, F., Varret, M., Slimane, M.N.

“…Les variations du gène de la lipoprotéine lipase peuvent contribuer à l’athérosclérose et aux maladies coronariennes. Le but de ce travail est d’examiner les…”
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L’hypercholestérolémie familiale en Tunisie by Jelassi, A., Jguirim, I., Najah, M., Maatouk, F., Hamda, K. Ben, Slimane, M.N.

“…L’hypercholestérolémie familiale ou l’hypercholestérolémie autosomique dominante est une pathologie caractérisée par une augmentation exclusive des…”
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Lipids--lipoproteins--apolipoproteins--risk markers in atherosclerosis by Slimane, M N, Bouslama, A, Maatoug, F, Hammami, M, Ben Farhat, M H

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