Search Results - "Sligl, Wendy I."

Do COVID-19 Infections Result in a Different Form of Secondary Hemophagocytic Lymphohistiocytosis by Chu, Raymond, van Eeden, Charmaine, Suresh, Sneha, Sligl, Wendy I, Osman, Mohammed, Cohen Tervaert, Jan Willem

“…The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in significant morbidity…”
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Safety and Efficacy of Corticosteroids for the Treatment of Septic Shock: A Systematic Review and Meta-Analysis by Sligl, Wendy I., Milner, Danny A., Sundar, Sugantha, Mphatswe, Wendy, Majumdar, Sumit R.

“…Background. Septic shock is common and results in significant morbidity and mortality. Adjunctive treatment with corticosteroids is common, but definitive data…”
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Severe Community-Acquired Pneumonia by Sligl, Wendy I., MD, MSc, FRCPC, Marrie, Thomas J., MD, FRCPC, MACP

“…Severe community-acquired pneumonia necessitating intensive care unit admission is associated with high morbidity, mortality, and health-care cost. This review…”
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Association Between Cytomegalovirus Reactivation and Clinical Outcomes in Immunocompetent Critically Ill Patients: A Systematic Review and Meta-Analysis by Lachance, Philippe, Chen, Justin, Featherstone, Robin, Sligl, Wendy I

“…The aim of our systematic review was to investigate the association between cytomegalovirus (CMV) reactivation and outcomes in immunocompetent critically ill…”
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The Prevention of Critical Care Complications in Coronary Intensive Care Unit: Protocols, Bundles, and Insights from Intensive Care Studies by van Diepen, Sean, MD MSc, Sligl, Wendy I., MD MSc, Washam, Jeffrey B., PhamD, Gilchrist, Ian C., MD, Arora, Rakesh C., MD, PhD, Katz, Jason N., MD, MHS

“…Unstructured Abstract Over the last half century coronary care units have expanded from specialized ischemia arrhythmia monitoring units into intensive care…”
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Epidemiology and Outcomes in Critically Ill Patients with Human Immunodeficiency Virus Infection in the Era of Combination Antiretroviral Therapy by Sligl, Wendy I., Eurich, Dean T., Bagshaw, Sean M., Turvey, Shannon L.

“…Purpose. The impact of critical illness on survival of HIV-infected patients in the era of antiretroviral therapy remains uncertain. We describe the…”
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Antimicrobial stewardship, procalcitonin testing, and rapid blood-culture identification to optimize sepsis care in critically ill adult patients: A quality improvement initiative by Sligl, Wendy I, Chen, Justin Z, Wang, Xiaoming, Boehm, Cheyanne, Fong, Karen, Crick, Katelynn, Garrido Clua, Míriam, Codan, Cassidy, Dingle, Tanis C, Gregson, Daniel, Prosser, Connie, Sadrzadeh, Hossein, Yan, Charles, Chen, Guanmin, Tse-Chang, Alena, Garros, Daniel, Doig, Christopher J, Zygun, David, Opgenorth, Dawn, Conly, John M, Bagshaw, Sean M

“…We examined the effect of an antimicrobial stewardship program (ASP), procalcitonin testing and rapid blood-culture identification on hospital mortality in a…”
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Predicting in-hospital mortality in pneumonia-associated septic shock patients using a classification and regression tree: a nested cohort study by Speiser, Jaime L, Karvellas, Constantine J, Shumilak, Geoffery, Sligl, Wendy I, Mirzanejad, Yazdan, Gurka, Dave, Kumar, Aseem, Kumar, Anand

“…Pneumonia complicated by septic shock is associated with significant morbidity and mortality. Classification and regression tree methodology is an intuitive…”
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Defining COVID-19–associated pulmonary aspergillosis: systematic review and meta-analysis by Kariyawasam, Ruwandi M., Dingle, Tanis C., Kula, Brittany E., Vandermeer, Ben, Sligl, Wendy I., Schwartz, Ilan S.

“…Pulmonary aspergillosis may complicate coronavirus disease 2019 (COVID-19) and contribute to excess mortality in intensive care unit (ICU) patients. The…”
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Macrolides and Mortality in Critically Ill Patients With Community-Acquired Pneumonia: A Systematic Review and Meta-Analysis by Sligl, Wendy I, Asadi, Leyla, Eurich, Dean T, Tjosvold, Lisa, Marrie, Thomas J, Majumdar, Sumit R

“…OBJECTIVE:Some studies suggest better outcomes with macrolide therapy for critically ill patients with community-acquired pneumonia. To further explore this,…”
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Association between Mycoplasma and Ureaplasma airway positivity, ammonia levels, and outcomes post–lung transplantation: A prospective surveillance study by Buzo, Bruno F., Preiksaitis, Jutta K., Halloran, Kieran, Nagendran, Jayan, Townsend, Derek R., Zelyas, Nathan, Sligl, Wendy I.

“…Hyperammonemia syndrome (HS) is a rare complication with high mortality described after lung transplantation. Its pathophysiology is still unclear, but…”
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Adult-onset presentation of a urea cycle disorder necessitating intensive care unit admission by Anderson, Dustin, Jain-Ghai, Shailly, Sligl, Wendy I.

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Macrolide-Based Regimens and Mortality in Hospitalized Patients With Community-Acquired Pneumonia: A Systematic Review and Meta-analysis by Asadi, Leyla, Sligl, Wendy I., Eurich, Dean T., Colmers, Isabelle N., Tjosvold, Lisa, Marrie, Thomas J., Majumdar, Sumit R.

“…Background. Macrolides are used to treat pneumonia despite increasing antimicrobial resistance. However, the immunomodulatory properties of macrolides may have…”
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Hyperammonemia syndrome post‐lung transplantation: Case series and systematic review of literature by Buzo, Bruno Fernando, Preiksaitis, Jutta K., Halloran, Kieran, Nagendran, Jayan, Townsend, Derek R., Zelyas, Nathan, Sligl, Wendy I.

“…Background Hyperammonemia syndrome (HS) is a rare post‐transplant complication associated with high morbidity and mortality. Its incidence appears to be higher…”
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Modelling the potential increase in eligible participants in clinical trials with inclusion of community intensive care unit patients in Alberta, Canada: a decision tree analysis by Quigley, Nicholas, Binnie, Alexandra, Baig, Nadia, Opgenorth, Dawn, Senaratne, Janek, Sligl, Wendy I., Zuege, Danny J., Rewa, Oleksa, Bagshaw, Sean M., Tsang, Jennifer, Lau, Vincent I.

“…Purpose Critical care research in Canada is conducted primarily in academically affiliated intensive care units (ICUs) with established research…”
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Detection of SARS-CoV-2 antibodies formed in response to the BNT162b2 and mRNA-1237 mRNA vaccine by commercial antibody tests by Kanji, Jamil N., Bailey, Ashley, Fenton, Jayne, Ling, Sean H., Rivera, Rafael, Plitt, Sabrina, Sligl, Wendy I., Taylor, Sean, Turnbull, LeeAnn, Tipples, Graham, Charlton, Carmen L.

“…With rapid approval of SARS-CoV-2 vaccines, the ability of clinical laboratories to detect vaccine-induced antibodies with available high-throughput commercial…”
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Macrolide use in the treatment of critically ill patients with pneumonia: Incidence, correlates, timing and outcomes by Sligl, Wendy I, Hoang, Holly, Eurich, Dean T, Malhotra, Atul, Marrie, Thomas J, Majumdar, Sumit R

“…Macrolide antibiotics are commonly used to treat pneumonia despite increasing antimicrobial resistance. Evidence suggests that macrolides may also decrease…”
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Moving Past the Routine Use of Macrolides—Reviewing the Role of Combination Therapy in Community-Acquired Pneumonia by Shumilak, Geoffrey, Sligl, Wendy I.

“…Purpose of Review Despite advances in diagnostic microbiology and sepsis management, community-acquired pneumonia (CAP) remains a significant cause of…”
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Community-acquired pneumonia by Remington, Leah T, Sligl, Wendy I

“…PURPOSE OF REVIEWThis review examines the epidemiology, diagnosis, prognosis, treatment and prevention of community-acquired pneumonia (CAP) in adults. RECENT…”
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Age still matters: Prognosticating short- and long-term mortality for critically ill patients with pneumonia by Sligl, Wendy I, Eurich, Dean T, Marrie, Thomas J, Majumdar, Sumit R

“…OBJECTIVE:To determine the association between age and mortality in critically ill patients with pneumonia. We hypothesized that increasing age would be…”
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