Search Results - "Sletten, Knut"

Fibril protein fragmentation pattern in systemic AL-amyloidosis by Enqvist, Stina, Sletten, Knut, Westermark, Per

“…Immunoglobulin light chain (AL)‐amyloidosis was one of the first types of amyloidosis discovered and still little is known about its pathogenic mechanisms. One…”
Get full text

Germ line origin and somatic mutations determine the target tissues in systemic AL-amyloidosis by Enqvist, Stina, Sletten, Knut, Stevens, Fred J, Hellman, Ulf, Westermark, Per

“…Amyloid is insoluble aggregated proteins deposited in the extra cellular space. About 25 different proteins are known to form amyloid in vivo and are…”
Get full text

Unwinding fibril formation of medin, the peptide of the most common form of human amyloid by Larsson, Annika, Söderberg, Linda, Westermark, Gunilla T., Sletten, Knut, Engström, Ulla, Tjernberg, Lars O., Näslund, Jan, Westermark, Per

“…Medin amyloid affects the medial layer of the thoracic aorta of most people above 50 years of age. The consequences of this amyloid are not completely known…”
Get full text

Elucidation of the Primary and Three-Dimensional Structure of the Uterotonic Polypeptide Kalata B1 by Saether, Olav, Craik, David J, Campbell, Iain D, Sletten, Knut, Juul, Jessie, Norman, David G

“…The amino acid sequence and structure of a uterotonic polypeptide extracted from the African plant Oldenlandia affinis DC have been determined. The peptide,…”
Get full text

Medin: An Integral Fragment of Aortic Smooth Muscle Cell-Produced Lactadherin Forms the Most Common Human Amyloid by Häggqvist, Bo, Näslund, Jan, Sletten, Knut, Westermark, Gunilla T., Mucchiano, Gerd, Tjernberg, Lars O., Nordstedt, Christer, Engström, Ulla, Westermark, Per

“…Aortic medial amyloid is a form of localized amyloid that occurs in virtually all individuals older than 60 years. The importance and impact of the amyloid…”
Get full text

Proteolysis of AA Amyloid Fibril Proteins by Matrix Metalloproteinases-1, -2, and -3 by Stix, Barbara, Kähne, Thilo, Sletten, Knut, Raynes, John, Roessner, Albert, Röcken, Christoph

“…We recently demonstrated the presence of matrix metalloproteinases (MMPs)-1, -2, and -3 in AA amyloid deposits, which lead us to speculate that MMPs may…”
Get full text

Chemical typing of amyloid protein contained in formalin-fixed paraffin-embedded biopsy specimens by MURPHY, Charles L, EULITZ, Manfred, SOLOMON, Alan, HRNCIC, Rudi, SLETTEN, Knut, WESTERMARK, Per, WILLIAMS, Teresa, MACY, Sallie D, WOOLIVER, Craig, WALL, Jonathan, WEISS, Deborah T

“…The human amyloidoses represent a heterogeneous group of disorders characterized by the deposition of fibrillar protein in vital organs. Given the fact that at…”
Get full text

Cleavage of AL amyloid proteins and AL amyloid deposits by cathepsins B, K, and L by Bohne, Silvia, Sletten, Knut, Menard, Robert, Bühling, Frank, Vöckler, Steffi, Wrenger, Eike, Roessner, Albert, Röcken, Christoph

“…Cathepsin (Cath) B, CathK and CathL are cysteine proteases that participate in the lysosomal protein degradation system and are expressed in macrophages,…”
Get full text

A father and his son with systemic AL amyloidosis by Enqvist, Stina, Mellqvist, Ulf-Henrik, Mölne, Johan, Sletten, Knut, Murphy, Charles, Solomon, Alan, Stevens, Fred J, Westermark, Per

Get full text

Lactadherin binds to elastin - a starting point for medin amyloid formation? by Larsson, Annika, Peng, Siwei, Persson, Helena, Rosenbloom, Joel, Abrams, William R., Wassberg, Erik, Thelin, Stefan, Sletten, Knut, Gerwins, Pär, Westermark, Per

“…Medin amyloid is found in the medial layer of the aorta in almost 100% of the Caucasian population over 50 years of age. The medin fragment is 5.5 kDa and…”
Get full text

A novel peptide in the calcitonin gene related peptide family as an amyloid fibril protein in the endocrine pancreas by Westermark, P, Wernstedt, C, Wilander, E, Sletten, K

“…Deposition of amyloid is the most constantly present alteration in the islets of Langerhans in type 2 diabetes mellitus and is also quite common in…”
Get more information

Cyclic Peptides from Oldenlandia affinis DC. Molecular and Biological Properties by Gran, Lorents, Sletten, Knut, Skjeldal, Lars

“…A new isolation procedure for Kalata polypeptides from the tropical plant Oldenlandia affinis DC is described. Fractions were screened by thin‐layer…”
Get full text

Monoclonal Antibodies Against Streptococcus Pneumoniae Detect Epitopes on Eubacterial Ribosomal Proteins L7/L12 and on Streptococcal Elongation Factor Ts by Kolberg, Jan, Hoiby, E. Arne, Lopez, Rodrigo, Sletten, Knut

“…1 National Institute of Public Health, Departments of Vaccinology, PO Box 4404 Torshov, N-0403 Oslo, Norway 2 National Institute of Public Health, Departments…”
Get full text

What is the role of giant cells in AL-amyloidosis? by Olsen, Karen Ege, Sletten, Knut, Sandgren, Ola, Olsson, Hans, Myrvo, Kristina, Westermark, Per

“…AL-amyloidosis is one of the most common amyloidoses and can be found in a localized and a systemic form. The precursor protein is an immunoglobulin light…”
Get full text

Amyloid deposits in transthyretin-derived amyloidosis: cleaved transthyretin is associated with distinct amyloid morphology by Bergström, Joakim, Gustavsson, Åsa, Hellman, Ulf, Sletten, Knut, Murphy, Charles L, Weiss, Deborah T, Solomon, Alan, Olofsson, Bert-Ove, Westermark, Per

“…The pathological fibrillar deposits found in the heart and other organs of patients with senile systemic amyloidosis (SSA) and Swedish familial amyloidotic…”
Get full text

Chemical and clinical classification of amyloidosis 1985 by Husby, G, Sletten, K

Get more information

Isolation of serum amyloid A protein by small-scale hydrophobic interaction chromatography and two-dimensional electrophoresis by Bruun, Cathrine Foyn, Sletten, Knut, Mehlum, Anja, Marhaug, Gudmund

“…A recently introduced technique to isolate serum amyloid A protein is hydrophobic interaction chromatography combined with two-dimensional electrophoresis with…”
Get full text

Apolipoprotein A-1-derived amyloid in atherosclerotic plaques of the human aorta by Mucchiano, Gerd I., Häggqvist, Bo, Sletten, Knut, Westermark, Per

Get full text

Cloning and sequencing of the gene encoding the phosphatidylcholine-preferring phospholipase C of Bacillus cereus by Johansen, T, Holm, T, Guddal, P H, Sletten, K, Haugli, F B, Little, C

“…A synthetic oligodeoxynucleotide probe was used to clone the gene encoding the phosphatidylcholine-preferring phospholipase C of Bacillus cereus. The sequence…”
Get more information

Oldenlandia affinis (R&S) DC : A plant containing uteroactive peptides used in African traditional medicine by Gran, Lorents, Sandberg, Finn, Sletten, Knut

“…A review of the geographical distribution, clinical use, biological activity and phytochemistry of Oldenlandia affinis (R&S) DC. is presented. During an…”
Get full text