Search Results - "Slemmon, R."

Two-Year Prognostic Utility of Plasma p217+tau across the Alzheimer’s Continuum by Feizpour, A., Doré, V., Doecke, J. D., Saad, Z. S., Triana-Baltzer, G., Slemmon, R., Maruff, P., Krishnadas, N., Bourgeat, P., Huang, K., Fowler, C., Rainey-Smith, S. R., Bush, A. I., Ward, L., Robertson, J., Martins, R. N., Masters, C. L., Villemagne, V. L., Fripp, J., Kolb, H. C., Rowe, Christopher C.

“…Background Plasma p217+tau has shown high concordance with cerebrospinal fluid (CSF) and positron emission tomography (PET) measures of amyloid-β (Aβ) and tau…”
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Increased levels of hemoglobin-derived and other peptides in Alzheimer's disease cerebellum by Slemmon, JR, Hughes, CM, Campbell, GA, Flood, DG

“…Several studies point to the importance of peptides and proteolysis in Alzheimer's disease (AD). Because of its ability to study small proteins and peptides,…”
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Partial sequence of human plasma glutathione peroxidase and immunologic identification of milk glutathione peroxidase as the plasma enzyme by Avissar, N, Slemmon, J R, Palmer, I S, Cohen, H J

“…Plasma glutathione peroxidase (p-GSHPx) is a unique selenoglycoprotein. A hepatic cell line synthesizes both this extracellular form for secretion and the…”
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Cloning of Drosophila Choline Acetyltransferase cDNA by Itoh, Nobuyuki, Slemmon, J. Randall, Hawke, David H., Williamson, Rodney, Morita, Elaine, Itakura, Keiichi, Roberts, Eugene, Shively, John E., Crawford, Garrett D., Salvaterra, Paul M.

“…Choline acetyltransferase (EC 2.3.1.6) is the biosynthetic enzyme for the neurotransmitter acetylcholine. To isolate choline acetyltransferase cDNA clones, a…”
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Evidence for the transneuronal regulation of cerebellin biosynthesis in developing Purkinje cells by Slemmon, JR, Goldowitz, D, Blacher, R, Morgan, JI

“…We have investigated the expression of a unique class of neuropeptides, the cerebellins, in normal and neurodevelopmentally mutant mice. Employing HPLC…”
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An Integrated Ten-Pump, Eight-Channel Parallel LC/MS System for Automated High-Throughput Analysis of Proteins by Feng, Bingbing, McQueney, Michael S, Mezzasalma, Tara M, Slemmon, J. Randall

“…An integrated 10-pump eight-channel LC/MS system has been developed for automated high-throughput analysis of intact proteins in recombinant protein…”
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Cerebellin: A Quantifiable Marker for Purkinje Cell Maturation by Slemmon, J. Randall, Danho, Waleed, Hempstead, James L., Morgan, James I.

“…The cerebellum-specific hexadecapeptide cerebellin has been localized by immunocytochemical means to the perikarya and dendrites of cerebellar Purkinje cells…”
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Cerebellin and related postsynaptic peptides in the brain of normal and neurodevelopmentally mutant vertebrates by Morgan, J I, Slemmon, J R, Danho, W, Hempstead, J, Berrebi, A S, Mugnaini, E

“…The rat cerebellum was previously shown to contain two polypeptides, a hexadecapeptide termed cerebellin and an apparent metabolite des-Ser1-cerebellin. The…”
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Monoclonal antibodies selective for Drosophila melanogaster choline acetyltransferase by Crawford, G, Slemmon, J R, Salvaterra, P M

“…The newly developed monoclonal antibody technology was applied to the production of antibodies selective for Drosophila melanogaster choline acetyltransferase…”
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The dendritic peptide neurogranin can regulate a calmodulin-dependent target by Martzen, M R, Slemmon, J R

“…Neurogranin, a peptide capable of binding the calcium-poor form of calmodulin, was tested in vitro for its ability to modulate a typical calmodulin target. The…”
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Purification of choline acetyltransferase from Drosophila melanogaster by Slemmon, J R, Salvaterra, P M, Crawford, G D, Roberts, E

“…Choline acetyltransferase (EC 2.3.1.6) from Drosophila melanogaster (Canton S, wild type) was purified 12,500-fold to a final specific activity of 500 mumol…”
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Profiling of endogenous peptides as a tool for studying development and neurological disease by Slemmon, J. Randall, Wengenack, Thomas M., Flood, Dorothy G.

“…The use of a method to follow changes in endogenous peptide production, as they occur in biological studies, is an excellent complement to other molecular…”
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Quantitative analysis of peptide and protein changes in ischemic hippocampal tissue by HPLC by Wengenack, T M, Slemmon, J R, Ordy, J M

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Sequence analysis of a proteolyzed site in Drosophila choline acetyltransferase by Slemmon, J R

“…The amino terminal sequence of the 13-kilodalton (kD) polypeptide present in purified Drosophila acetyl-CoA: choline-O-acetyltransferase (EC 2.3.1.6) was…”
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Isolation and Sequencing of Two Cerebellum-Specific Peptides by Slemmon, J. Randall, Blacher, Russell, Danho, Waleed, Hempstead, James L., Morgan, James I.

“…By comparing the HPLC elution profiles of peptides isolated from different brain regions, two cerebellum-specific species have been identified. The peptides…”
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Identification of a neuronal calmodulin-binding peptide, CAP-19, containing an IQ motif by Smith, Michael L, Johanson, Roy A, Rogers, Kathryn E, Coleman, Paul D, Slemmon, J.Randall

“…Neurons produce polypeptides which can bind the calcium-poor or pre-activated form of calmodulin. It is expected that this class of peptide will serve an…”
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Vascular and cellular protein changes precede hippocampal pyramidal cell loss following global ischemia in the rat by Wengenack, T M, Slemmon, J R, Ordy, J M, Dunlap, W P, Coleman, P D

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Production of polyclonal antisera to choline acetyltransferase using a fusion protein produced by a cDNA clone by Muñoz-Maines, V J, Slemmon, J R, Panicker, M M, Neighbor, N, Salvaterra, P M

“…A fusion protein containing a Drosophila choline acetyltransferase (ChAT) cDNA insert was purified from a lambda gtll lysate of Escherichia coli. The cDNA…”
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Measurement of Aβ1-42 in cerebrospinal fluid is influenced by matrix effects by Slemmon, J. Randall, Meredith, Jere, Guss, Valerie, Andreasson, Ulf, Andreasen, Niels, Zetterberg, Henrik, Blennow, Kaj

“…J. Neurochem. (2012) 120, 325–333. Aβ1–42 measurement in CSF is an important biochemical marker for Alzheimer disease (AD). However, our understanding of why…”
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Small proteins that modulate calmodulin-dependent signal transduction: effects of PEP-19, neuromodulin, and neurogranin on enzyme activation and cellular homeostasis by Slemmon, J R, Feng, B, Erhardt, J A

“…Neuromodulin (GAP-43), neurogranin (RC3), and PEP-19 are small acid-stable proteins that bind calcium-poor calmodulin through a loosely conserved IQ-motif…”
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