Search Results - "Sleiman, Rayan"

Microskeletal stiffness promotes aortic aneurysm by sustaining pathological vascular smooth muscle cell mechanosensation via Piezo1 by Qian, Weiyi, Hadi, Tarik, Silvestro, Michele, Ma, Xiao, Rivera, Cristobal F., Bajpai, Apratim, Li, Rui, Zhang, Zijing, Qu, Hengdong, Tellaoui, Rayan Sleiman, Corsica, Annanina, Zias, Ariadne L., Garg, Karan, Maldonado, Thomas, Ramkhelawon, Bhama, Chen, Weiqiang

“…Mechanical overload of the vascular wall is a pathological hallmark of life-threatening abdominal aortic aneurysms (AAA). However, how this mechanical stress…”
Get full text

Lung-derived HMGB1 is detrimental for vascular remodeling of metabolically imbalanced arterial macrophages by Boytard, Ludovic, Hadi, Tarik, Silvestro, Michele, Qu, Hengdong, Kumpfbeck, Andrew, Sleiman, Rayan, Fils, Kissinger Hyppolite, Alebrahim, Dornazsadat, Boccalatte, Francesco, Kugler, Matthias, Corsica, Annanina, Gelb, Bruce E., Jacobowitz, Glenn, Miller, George, Bellini, Chiara, Oakes, Jessica, Silvestre, Jean-Sébastien, Zangi, Lior, Ramkhelawon, Bhama

“…Pulmonary disease increases the risk of developing abdominal aortic aneurysms (AAA). However, the mechanism underlying the pathological dialogue between the…”
Get full text

Mapping Semaphorins and Netrins in the Pathogenesis of Human Thoracic Aortic Aneurysms by Alebrahim, Dornazsadat, Nayak, Mangala, Ward, Alison, Ursomanno, Patricia, Shams, Rebecca, Corsica, Annanina, Sleiman, Rayan, Fils, Kissinger Hyppolite, Silvestro, Michele, Boytard, Ludovic, Hadi, Tarik, Gelb, Bruce, Ramkhelawon, Bhama

“…Thoracic aortic aneurysm (TAA) is a complex life-threatening disease characterized by extensive extracellular matrix (ECM) fragmentation and persistent…”
Get full text

The Nonproteolytic Intracellular Domain of Membrane-Type 1 Matrix Metalloproteinase Coordinately Modulates Abdominal Aortic Aneurysm and Atherosclerosis in Mice—Brief Report by Silvestro, Michele, Rivera, Cristobal F., Alebrahim, Dornazsadat, Vlahos, John, Pratama, Muhammad Yogi, Lu, Cuijie, Tang, Claudia, Harpel, Zander, Sleiman Tellaoui, Rayan, Zias, Ariadne L., Maldonado, Delphina J., Byrd, Devon, Attur, Mukundan, Mignatti, Paolo, Ramkhelawon, Bhama

“…MT1-MMP (membrane-type 1 matrix metalloproteinase, MMP-14) is a transmembrane-anchored protein with an extracellular proteinase domain and a cytoplasmic tail…”
Get full text

Abstract 15542: Immuno-Footprint of Myeloid Clusters in Human Abdominal Aortic Aneurysm by Silvestro, Michele, Rivera Martinez, Cristobal, Vlahos, John, Pratama, Muhammad Yogi, Kumari, Puja, Sleiman Tellaoui, Rayan, Maldonado, Thomas, Ramkhelawon, Bhama

“…Inflammation is a hallmark of abdominal aortic aneurysms (AAA) with central roles ascribed to myeloid lineage effector cells. However, the dynamics of…”
Get full text

Abstract 16808: Divergent Mature Vascular Smooth Muscle Cell Fates Are Directed by Platelet-Derived Transcriptomic Codes in Aortic Aneurysms by HADI, Tarik, Silvestro, Michele, Rivera Martinez, Cristobal, Sleiman Tellaoui, Rayan, zias, ariadne, Ramkhelawon, Bhama

“…IntroductionLoss of vascular smooth-muscle cells (vSMC) and subsequent defective replenishment of functional vSMC de novo are pathological hallmarks of…”
Get full text

Abstract 155: Divergent Mature Vascular Smooth Muscle Cell Fates Are Directed By Platelet-derived Transcriptomic Codes In Aortic Aneurysms by Pratama, Muhammad Yogi, Rivera Martinez, Cristobal, Silvestro, Michele, Vlahos, John, Zias, Ariadne, Byrd, Devon, Sleiman Tellaoui, Rayan, Maldonado, Thomas, Rhamkhelawon, Bhama

“…IntroductionLoss of vascular smooth-muscle cells (vSMC) and subsequent defective replenishment of functional vSMC de novo are pathological hallmarks of…”
Get full text

Nonproteolytic Intracellular Domain of MT1-MMP (Membrane-Type 1 Matrix Metalloproteinase) Coordinately Modulates Abdominal Aortic Aneurysm and Atherosclerosis to Mice by Silvestro, Michele, Rivera, Cristobal F., Alebrahim, Dornazsadat, Vlahos, John, Pratama, Muhammad Yogi, Lu, Cuijie, Tang, Claudia, Harpel, Zander, Sleiman Tellaoui, Rayan, Zias, Ariadne L., Maldonado, Delphina J., Byrd, Devon, Attur, Mukundan, Mignatti, Paolo, Ramkhelawon, Bhama

Get full text