Search Results - "Slavik, Ludek"

Monitoring of fibrinolytic system activity with plasminogen, D-dimers and FDP in primary total knee arthroplasty (TKA) after topical, intravenous or combined administration of tranexamic acid by Lostak, Jiri, Gallo, Jiri, Slavik, Ludek, Zapletalova, Jana, Balaz, Lubos

“…We assessed various ways of tranexamic acid (TXA) administration on the fibrinolytic system. Blood loss, transfusions, drainage and haematoma were secondary…”
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The Modern Pneumatic Tube System Transports with Reduced Speed Does Not Affect Special Coagulation Tests by Slavík, Luděk, Úlehlová, Jana, Bradáčová, Pavla, Chasáková, Kateřina, Hluší, Antonín, Palová, Miroslava, Entrová, Alice

“…Pneumatic tube transport systems (PTS) for delivery of patient samples to a hemostasis laboratory are often used to reduce turnaround time for vital analyses…”
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Current Promising Biomarkers and Methods in the Diagnostics of Antiphospholipid Syndrome: A Review by Bradacova, Pavla, Slavik, Ludek, Ulehlova, Jana, Skoumalova, Adela, Ullrychova, Jana, Prochazkova, Jana, Hlusi, Antonin, Manukyan, Gayane, Kriegova, Eva

“…Antiphospholipid syndrome (APS) is a hypercoagulation condition associated with the incidence of heterogenic antiphospholipid antibodies (aPLs), which…”
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Markers of endothelial activation in preeclampsia by Prochazka, Martin, Procházková, Jana, Lubušký, Marek, Pilka, Radovan, Úlehlová, Jana, Michalec, Igor, Polák, Petr, Kacerovský, Marian, Slavik, Luděk

“…The study aimed at finding a laboratory approach to detect endothelial damage in normal pregnancy as well as in pregnancy complicated by preeclampsia using…”
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The role of tissue factor in normal pregnancy and in the development of preeclampsia: A review by Prochazkova, Jana, Slavik, Ludek, Ulehlova, Jana, Prochazka, Martin

“…Tissue factor (TF) is a key element for normal gestation, especially in the first trimester. TF levels are hence raised in pregnancy, producing an adaptive…”
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17β-Estradiol Promotes Proinflammatory and Procoagulatory Phenotype of Innate Immune Cells in the Presence of Antiphospholipid Antibodies by Manukyan, Gayane, Martirosyan, Anush, Slavik, Ludek, Ulehlova, Jana, Dihel, Martin, Papajik, Tomas, Kriegova, Eva

“…Antiphospholipid syndrome (APS) is the most common cause of acquired thrombophilia and recurrent spontaneous miscarriages associated with extended persistence…”
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Anti-domain 1 β2 glycoprotein antibodies increase expression of tissue factor on monocytes and activate NK Cells and CD8+ cells in vitro by Manukyan, Gayane, Martirosyan, Anush, Slavik, Ludek, Margaryan, Sona, Ulehlova, Jana, Mikulkova, Zuzana, Hlusi, Antonin, Papajik, Tomas, Kriegova, Eva

“…β2-Glycoprotein I (β2GPI) represents the major antigenic target for antiphospholipid antibodies (aPL), with domain 1 (D1) being identified as a risk factor for…”
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Detection of Unknown and Rare Pathogenic Variants in Antithrombin, Protein C and Protein S Deficiency Using High-Throughput Targeted Sequencing by Vrtel, Petr, Slavik, Ludek, Vodicka, Radek, Stellmachova, Julia, Prochazka, Martin, Prochazkova, Jana, Ulehlova, Jana, Rohon, Peter, Simurda, Tomas, Stasko, Jan, Martinkova, Ivana, Vrtel, Radek

“…The deficiency of natural anticoagulants—antithrombin (AT), protein C (PC), and protein S (PS)—is a highly predisposing factor for thrombosis, which is still…”
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The prevalence of activated protein C (APC) resistance and factor V Leiden is significantly higher in patients with retinal vein occlusion without general risk factors. Case-control study and meta-analysis by Rehak, Matus, Rehak, Jiri, Müller, Marc, Faude, Susanne, Faude, Frank, Siegemund, Annelie, Krcova, Vera, Slavik, Ludek, Hasenclever, Dirk, Scholz, Markus, Wiedemann, Peter

“…Several small case-control studies have investigated whether factor V Leiden (FVL) is a risk factor for retinal vein occlusion (RVO) and generated conflicting…”
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The role of thrombophilia in patients with retinal vein occlusion and no systemic risk factors by Rehak, Matus, MD, PhD, Krcova, Vera, MD, PhD, Slavik, Ludek, PhD, Fric, Evzen, MD, Langova, Katerina, Ulehlova, Jana, Rehak, Jiri, MD, PhD

“…Abstract Objective: The role of thrombophilia in the etiology of retinal vein occlusion (RVO) has not been adequately clarified. The aim of this study was to…”
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The pathophysiology of endothelial function in pregnancy and the usefulness of endothelial markers by Slavik, Ludek, Prochazkova, Jana, Prochazka, Martin, Simetka, Ondrej, Hlusi, Antonin, Ulehlova, Jana

“…The aim of this study was to assess coagulation markers of endothelial damage and examine new markers of endothelial activation such as matrix…”
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Hypertriglyceridemic Waist in Patients with Type 2 Diabetes: Its Relationship to Selected Markers of Vascular Damage by Karasek, David, Spurna, Jaromira, Macakova, Dominika, Cibickova, Lubica, Krystynik, Ondrej, Kucerova, Veronika, Ulehlova, Jana, Slavik, Ludek

“…To evaluate the association between hypertriglyceridemic waist (HTGW), a promising marker of visceral adiposity and cardiovascular (CV) risk, and different…”
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The influence of apolipoprotein A5 T-1131C and apolipoprotein E common genetic variants on the levels of hemostatic markers in dyslipidemic patients by Novotny, Dalibor, Karasek, David, Vaverkova, Helena, Slavik, Ludek

“…The aim of this study was to evaluate the relationships of the T-1131C (rs662799) polymorphism variants of apolipoprotein A5 (Apo A5) gene and variants of…”
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A synergy of liquid chromatography with high‐resolution mass spectrometry and coagulation test for determination of direct oral anticoagulants for clinical and toxicological purposes by Maier, Vítězslav, Slavík, Luděk, Ondra, Peter

“…Direct oral anticoagulants are an alternative to anticoagulants based on vitamin K antagonists. Monitoring of direct oral anticoagulant concentration levels is…”
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Antiphospholipid antibody-mediated NK cell cytotoxicity by Manukyan, Gayane, Kriegova, Eva, Slavik, Ludek, Mikulkova, Zuzana, Ulehlova, Jana, Martirosyan, Anush, Papajik, Tomas

“…Antiphospholipid syndrome (APS) is an autoimmune thrombophilia that is characterised by thrombosis and obstetric complications in the presence of…”
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Genetic polymorphisms of platelet receptors in patients with acute myocardial infarction and resistance to antiplatelet therapy by Ulehlova, Jana, Slavik, Ludek, Kucerova, Jana, Krcova, Vera, Vaclavik, Jan, Indrak, Karel

“…The studied group comprises 124 patients with acute myocardial infarction on dual antiplatelet therapy with acetylsalicylic acid (ASA) and thienopyridines…”
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Possibility of Coagulation System Activation Determination with Tissue Factor in Pregnancy Complications by Slavik, Ludek, Novak, Martin, Ulehlova, Jana, Prochazka, Martin, Prochazkova, Jana, Lattova, Veronika, Polak, Petr, Pilka, Radovan

“…In this part of the study, where we determined the causes of preeclampsia and other obstetric complications, we focused on the role of tissue factor (TF) in…”
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Positive association of adiponectin with soluble thrombomodulin, von Willebrand factor and soluble VCAM-1 in dyslipidemic subjects by Vaverkova, Helena, Karasek, David, Novotny, Dalibor, Kovarova, Dagmar, Halenka, Milan, Slavik, Ludek, Frohlich, Jiri

“…Both decreased and increased risk of cardiovascular events/mortality have been reported with high adiponectin levels. Only a few studies have reported an…”
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Determination of Thrombogenicity Levels of Various Antiphospholipid Antibodies by a Modified Thrombin Generation Assay in Patients with Suspected Antiphospholipid Syndrome by Bradáčová, Pavla, Slavík, Luděk, Skoumalová, Adéla, Úlehlová, Jana, Kriegová, Eva, Manukyan, Gayane, Friedecký, David, Piskláková, Barbora, Ullrychová, Jana, Procházková, Jana, Hluší, Antonín

“…Antiphospholipid syndrome (APS) is a hypercoagulable state accompanied by the presence of heterogeneous antiphospholipid antibodies (aPL), which…”
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Polymorphism of the Fcγ Receptor II as a Possible Predisposing Factor for Heparin-Induced Thrombocytopenia by Slavik, Ludek, Svobodova, Gabriela, Ulehlova, Jana, Krcova, Vera, Hlusi, Antonin, Prochazkova, Jana, Hutyra, Martin

“…Heparin-induced thrombocytopenia (HIT) represents a serious complication of heparin treatment. IgG antibodies binding platelet factor 4 (PF4) and heparin…”
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