Search Results - "Slaughter, Malcolm M"

Properties of a Glutamatergic Synapse Controlling Information Output from Retinal Bipolar Cells by Sethuramanujam, Santhosh, Slaughter, Malcolm M

“…One general categorization of retinal ganglion cells is to segregate them into tonically or phasically responding neurons, each conveying discrete aspects of…”
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Saccharin and aspartame excite rat retinal neurons by Yang, Jaeyoung, Myers, Jason, Slaughter, Malcolm M

“…Retinal sensitivity to a variety of artificial sweeteners was tested by monitoring changes in internal free calcium in isolated retinal neurons using Fluo3…”
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Synaptic Transmission Mediated by Internal Calcium Stores in Rod Photoreceptors by Suryanarayanan, Anuradha, Slaughter, Malcolm M

“…Retinal rod photoreceptors are depolarized in darkness to approximately -40 mV, a state in which they maintain sustained glutamate release despite low levels…”
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Caffeine inhibition of ionotropic glycine receptors by Duan, Lei, Yang, Jaeyoung, Slaughter, Malcolm M.

“…We found that caffeine is a structural analogue of strychnine and a competitive antagonist at ionotropic glycine receptors (GlyRs). Docking simulations…”
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Origin of Transient and Sustained Responses in Ganglion Cells of the Retina by Awatramani, Gautam B, Slaughter, Malcolm M

“…Phasic and tonic light responses provide a fundamental division of visual information that is thought to originate in the inner retina. However, evidence…”
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Effects of GABA Receptor Antagonists on Retinal Glycine Receptors and on Homomeric Glycine Receptor Alpha Subunits by Wang, Peiyuan, Slaughter, Malcolm M

“…Department of Physiology and Biophysics, School of Medicine, University at Buffalo, Buffalo, New York Submitted 1 December 2004; accepted in final form 30…”
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GABAB receptor attenuation of GABAA currents in neurons of the mammalian central nervous system by Shen, Wen, Nan, Changlong, Nelson, Peter T, Ripps, Harris, Slaughter, Malcolm M

“…Ionotropic receptors are tightly regulated by second messenger systems and are often present along with their metabotropic counterparts on a neuron's plasma…”
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Synaptic inhibition by glycine acting at a metabotropic receptor in tiger salamander retina by Hou, Mingli, Duan, Lei, Slaughter, Malcolm M.

“…Glycine is the lone fast neurotransmitter for which a metabotropic pathway has not been identified. In retina, we found a strychnine-insensitive glycine…”
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GABAB receptors enhance excitatory responses in isolated rat retinal ganglion cells by Garaycochea, Jay, Slaughter, Malcolm M.

“…Key points GABA is an inhibitory transmitter but can sometimes produce paradoxical excitatory effects through synaptic networks. We found a novel GABA‐mediated…”
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Cholinergic excitation complements glutamate in coding visual information in retinal ganglion cells by Sethuramanujam, Santhosh, Awatramani, Gautam B., Slaughter, Malcolm M.

“…Key points Starburst amacrine cells release GABA and ACh. This study explores the coordinated function of starburst‐mediated cholinergic excitation and…”
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A dark decrement for enhanced dynamic sensitivity of retinal photoreceptors by Hu, Shen, Anastassov, Ivan A, Kreitzer, Matthew A, Slaughter, Malcolm M, Chappell, Richard L

“…The skate retina provides a native all-rod retina suited for investigating a single type of photoreceptor regarding its properties and signaling to second…”
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Kainate receptors: on the dark side by Slaughter, Malcolm M.

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Disinhibitory recruitment of NMDA receptor pathways in retina by Sethuramanujam, Santhosh, Slaughter, Malcolm M

“…Glutamate release at bipolar to ganglion cell synapses activates NMDA and AMPA/kainic acid (KA) ionotropic glutamate receptors. Their relative strength…”
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Golgi meet Cajal: coupling and feedback at retinal photoreceptors by Slaughter, Malcolm M.

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Selective antagonism of rat inhibitory glycine receptor subunits by Han, Yi, Li, Ping, Slaughter, Malcolm M.

“…Retinal ganglion cells exhibit fast and slow inhibitory synaptic glycine currents that can be selectively inhibited by strychnine and 5,7-dichlorokynurenic…”
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Metabotropic GABA receptors facilitate L-type and inhibit N-type calcium channels in single salamander retinal neurons by Shen, Wen, Slaughter, Malcolm M.

“…Whole-cell voltage clamp experiments were performed on isolated spiking retinal neurons from the salamander retina. Calcium channel currents were studied using…”
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Multireceptor GABAergic regulation of synaptic communication in amphibian retina by Shen, Wen, Slaughter, Malcolm M.

“…The synaptic output of retinal bipolar cells was monitored by recording light-evoked EPSCs in ganglion cells. Application of ( RS)-…”
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Mechanism of generation of spontaneous miniature outward currents (SMOCs) in retinal amacrine cells by Mitra, Pratip, Slaughter, Malcolm M

“…A subtype of retinal amacrine cells displayed a distinctive array of K(+) currents. Spontaneous miniature outward currents (SMOCs) were observed in the narrow…”
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Photoreceptor encoding of supersaturating light stimuli in salamander retina by Xu, Jian Wei, Hou, Mingli, Slaughter, Malcolm M.

“…In the dark-adapted salamander retina, spikes could be elicited from rods under normal physiological conditions. Spike activity was observed in rods during the…”
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GABA(B) receptor feedback regulation of bipolar cell transmitter release by Song, Yunbo, Slaughter, Malcolm M

“…GABAergic amacrine cell feedback to bipolar cells in retina has been described, activating both GABA(A) and GABA(C) receptors. We explored whether metabotropic…”
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