Search Results - "Slater, Nigel K.H."

The role of hydrophobic amino acid grafts in the enhancement of membrane-disruptive activity of pH-responsive pseudo-peptides by Chen, Rongjun, Khormaee, Sariah, Eccleston, Mark E, Slater, Nigel K.H

“…Abstract pH-responsive polymers have been synthesised by grafting l -valine (PV-75), l -leucine (PL-75) and l -phenylalanine (PP-75) onto the pendant…”
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Generation and manipulation of magnetic multicellular spheroids by Ho, Vincent H.B, Müller, Karin H, Barcza, Alexander, Chen, Rongjun, Slater, Nigel K.H

“…Abstract Multicellular spheroids have important applications in tumour studies, drug screening and tissue engineering. To enable simple manipulation of…”
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Fluorescence intensity and lifetime imaging of free and micellar-encapsulated doxorubicin in living cells by Dai, Xiaowen, BEng, Yue, Zhilian, PhD, Eccleston, Mark E., PhD, Swartling, Johannes, PhD, Slater, Nigel K.H., PhD, Kaminski, Clemens F., PhD

“…Abstract Frequency domain fluorescence lifetime imaging microscopy (FLIM) has been used in combination with laser scanning confocal microscopy to study the…”
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Protection of live bacteria from bile acid toxicity using bile acid adsorbing resins by Edwards, Alexander D, Slater, Nigel K.H

“…Abstract We previously demonstrated that a dry, room temperature stable formulation of a live bacterial vaccine was highly susceptible to bile, and suggested…”
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Effect of Magnetite Nanoparticle Agglomerates on Ultrasound Induced Inertial Cavitation by Smith, Moira J, Ho, Vincent H.B, Darton, Nicholas J, Slater, Nigel K.H

“…Abstract High intensity focused ultrasound (HIFU) induced inertial cavitation has been shown to improve release and cellular uptake of drugs. The effects of…”
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Enhancing the functionality of a microscale bioreactor system as an industrial process development tool for mammalian perfusion culture by Sewell, David J, Turner, Richard, Field, Ray, Holmes, William, Pradhan, Rahul, Spencer, Christopher, Oliver, Stephen G, Slater, Nigel KH, Dikicioglu, Duygu

“…Without a scale‐down model for perfusion, high resource demand makes cell line screening or process development challenging, therefore, potentially successful…”
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pH-responsive polymers for trehalose loading and desiccation protection of human red blood cells by Lynch, Andrew L, Chen, Rongjun, Slater, Nigel K.H

“…Abstract PP-50, a synthetic pH-responsive biopolymer, is here shown to increase the permeability of the phospholipid bilayer to trehalose, a disaccharide…”
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Cryopreservation of Red Blood Cells by Al-Otaibi, Noha A S, Slater, Nigel K H, Rahmoune, Hassan

“…Glycerol and trehalose are widely used protective agents in the cryopreservation of red blood cells (RBCs). This chapter presents a protocol for use of these…”
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Molecular Characterization of Human Leukemia 60 (HL-60) Cells as a Model of Acute Myelogenous Leukemia Post Cryopreservation by Al-Otaibi, Noha A S, Cassoli, Juliana S, Slater, Nigel K H, Rahmoune, Hassan

“…The use of human leukemic (HL)-60 cells is important for studies of acute myeloid leukemia (AML) and as a model system for investigating how specific types of…”
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Rational Nanotoolbox with Theranostic Potential for Medicated Pro‐Regenerative Corneal Implants by Patra, Hirak K., Azharuddin, Mohammad, Islam, Mohammad M., Papapavlou, Georgia, Deb, Suryyani, Osterrieth, Johannes, Zhu, Geyunjian Harry, Romu, Thobias, Dhara, Ashis K., Jafari, Mohammad J., Ghaderi, Amineh, Hinkula, Jorma, Rajan, Madhavan S., Slater, Nigel K. H.

“…Cornea diseases are a leading cause of blindness and the disease burden is exacerbated by the increasing shortage around the world for cadaveric donor corneas…”
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pH-responsive endosomolytic pseudo-peptides for drug delivery to multicellular spheroids tumour models by Ho, Vincent H.B, Slater, Nigel K.H, Chen, Rongjun

“…Abstract Endosomolytic polymers can aid in the endosomal release of therapeutics to improve intracellular drug delivery. pH-responsive biomimetic…”
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Biopolymer mediated trehalose uptake for enhanced erythrocyte cryosurvival by Lynch, Andrew L, Chen, Rongjun, Dominowski, Paul J, Shalaev, Evgenyi Y, Yancey, Robert J, Slater, Nigel K.H

“…Abstract A biopolymer has been shown to facilitate efficient delivery of trehalose, a bioprotectant normally impermeable to the phospholipid bilayer, into…”
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An esterase-responsive ibuprofen nano-micelle pre-modified embryo derived nucleus pulposus progenitor cells promote the regeneration of intervertebral disc degeneration by Xia, Kai-shun, Li, Dong-dong, Wang, Cheng-gui, Ying, Li-wei, Wang, Jing-kai, Yang, Biao, Shu, Jia-wei, Huang, Xian-peng, Zhang, Yu-ang, Yu, Chao, Zhou, Xiao-peng, Li, Fang-cai, Slater, Nigel K.H., Tang, Jian-bin, Chen, Qi-xin, Liang, Cheng-zhen

“…Stem cell-based transplantation is a promising therapeutic approach for intervertebral disc degeneration (IDD). Current limitations of stem cells include with…”
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A nipple shield delivery system for oral drug delivery to breastfeeding infants: Microbicide delivery to inactivate HIV by Gerrard, Stephen E., Baniecki, Mary Lynn, Sokal, David C., Morris, Mary K., Urdaneta-Hartmann, Sandra, Krebs, Fred C., Wigdahl, Brian, Abrams, Barbara F., Hanson, Carl V., Slater, Nigel K.H., Edwards, Alexander D.

“…Cross sectional diagram of milk leaving breast passing through nipple shield delivery system insert. A new drug delivery method for infants is presented which…”
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Effect of Magnetite Nanoparticle Agglomerates on the Destruction of Tumor Spheroids Using High Intensity Focused Ultrasound by Ho, Vincent H.B, Smith, Moira J, Slater, Nigel K.H

“…Abstract Magnetite (Fe3 O4 ) nanoparticle agglomerates have been shown to enhance the degree of inertial cavitation induced by high-intensity focused…”
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The precise control of cell labelling with streptavidin paramagnetic particles by Ho, Vincent H.B, Barcza, Alexander, Chen, Rongjun, Müller, Karin H, Darton, Nicholas J, Slater, Nigel K.H

“…Abstract A previously developed cell labelling methodology has been evaluated to assess its potential to precisely control the degree of magnetic labelling…”
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Aqueous solution behaviour and membrane disruptive activity of pH-responsive PEGylated pseudo-peptides and their intracellular distribution by Chen, Rongjun, Yue, Zhilian, Eccleston, Mark E, Slater, Nigel K.H

“…Abstract The effect of PEGylation on the aqueous solution properties and cell membrane disruptive activity of a pH-responsive pseudo-peptide, poly( l -lysine…”
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In situ fabrication of a microfluidic device for immobilised metal affinity sensing by Deshpande, Abhishek G., Darton, Nicholas J., Yunus, Kamran, Fisher, Adrian C., Slater, Nigel K.H.

“…► New microfluidic device constructed in situ for high-throughput in-process protein monitoring. ► Device contains smallest co-polymeric immobilised metal…”
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Formulation of a live bacterial vaccine for stable room temperature storage results in loss of acid, bile and bile salt resistance by Edwards, Alexander D, Slater, Nigel K.H

“…Abstract Live bacterial vaccines have great promise both as vaccines against enteric pathogens and as heterologous antigen vectors against diverse diseases…”
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Metabolic Biotinylation of Lentiviral Pseudotypes for Scalable Paramagnetic Microparticle-Dependent Manipulation by Nesbeth, Darren, Williams, Sharon L, Chan, Lucas, Brain, Tony, Slater, Nigel K H, Farzaneh, Farzin, Darling, David

“…Nonviral, host-derived proteins on lentiviral vector surfaces can have a profound effect on the vector's biology as they can both promote infection and provide…”
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