Search Results - "Slater, Nigel"

Pharmaceutical Development of AAV-Based Gene Therapy Products for the Eye by Rodrigues, Gerard A., Shalaev, Evgenyi, Karami, Thomas K., Cunningham, James, Slater, Nigel K. H., Rivers, Hongwen M.

“…A resurgence of interest and investment in the field of gene therapy, driven in large part by advances in viral vector technology, has recently culminated in…”
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A MnO2 Nanoparticle-Dotted Hydrogel Promotes Spinal Cord Repair via Regulating Reactive Oxygen Species Microenvironment and Synergizing with Mesenchymal Stem Cells by Li, Liming, Xiao, Bing, Mu, Jiafu, Zhang, Yu, Zhang, Chenyang, Cao, Hongcui, Chen, Rongjun, Patra, Hirak Kumar, Yang, Bo, Feng, Shiqing, Tabata, Yasuhiko, Slater, Nigel K. H, Tang, Jianbin, Shen, Youqing, Gao, Jianqing

“…Spinal cord injury (SCI) is one of the most debilitating injuries, and transplantation of stem cells in a scaffold is a promising strategy for treatment…”
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Amorphous metal-organic frameworks for drug delivery by Orellana-Tavra, Claudia, Baxter, Emma F, Tian, Tian, Bennett, Thomas D, Slater, Nigel K H, Cheetham, Anthony K, Fairen-Jimenez, David

“…We report the encapsulation of the hydrophilic model molecule calcein in the Zr-based MOF UiO-66, followed by amorphization of the framework by ball-milling…”
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Glutathione-Responsive Magnetic Nanoparticles for Highly Sensitive Diagnosis of Liver Metastases by Xu, Xiaodan, Zhou, Xiaoxuan, Xiao, Bing, Xu, Hongxia, Hu, Doudou, Qian, Yue, Hu, Hongjie, Zhou, Zhuxian, Liu, Xiangrui, Gao, Jianqing, Slater, Nigel K. H, Shen, Youqing, Tang, Jianbin

“…Liver metastasis (LM) occurs in various cancers, and its early and accurate diagnosis is of great importance. However, the detection of small LMs is still a…”
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Nano toolbox in immune modulation and nanovaccines by Azharuddin, Mohammad, Zhu, Geyunjian Harry, Sengupta, Anirban, Hinkula, Jorma, Slater, Nigel K.H., Patra, Hirak K.

“…Despite the great success of vaccines over two centuries, the conventional strategy is based on attenuated/altered microorganisms. However, this is not…”
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Drug delivery from a solid formulation during breastfeeding-A feasibility study with mothers and infants by Maier, Theresa, Peirce, Paula, Baird, Laura, Whitehouse, Sophie L, Slater, Nigel K H, Beardsall, Kathryn

“…Breastfeeding is critical to health outcomes, particularly in low-resource settings where there is little access to clean water. For infants in their first…”
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Salidroside as a Novel Protective Agent to Improve Red Blood Cell Cryopreservation by Alotaibi, Noha A S, Slater, Nigel K H, Rahmoune, Hassan

“…Glycerol and trehalose have been widely examined as protective agents in the cryopreservation of red blood cells (RBCs). However, the effectiveness of these…”
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pH-responsive polymers for trehalose loading and desiccation protection of human red blood cells by Lynch, Andrew L, Chen, Rongjun, Slater, Nigel K.H

“…Abstract PP-50, a synthetic pH-responsive biopolymer, is here shown to increase the permeability of the phospholipid bilayer to trehalose, a disaccharide…”
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Highly Sensitive Imaging of Tumor Metastasis Based on the Targeting and Polarization of M2-like Macrophages by Yuan, Pengcheng, Xu, Xiaodan, Hu, Doudou, Chen, Yong, Fan, Jiaqi, Yao, Shasha, Piao, Ying, Zhou, Zhuxian, Shao, Shiqun, Slater, Nigel K. H., Shen, Youqing, Tang, Jianbin

“…Tumor-associated macrophages, especially M2-like macrophages, are extensively involved in tumor growth and metastasis, suppressing the innate immunity to help…”
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An MRI-trackable therapeutic nanovaccine preventing cancer liver metastasis by Xiao, Bing, Li, Dongdong, Xu, Hongxia, Zhou, Xiaoxuan, Xu, Xiaodan, Qian, Yue, Yu, Feidan, Hu, Hongjie, Zhou, Zhuxian, Liu, Xiangrui, Gao, Jianqing, Slater, Nigel K.H., Shen, Youqing, Tang, Jianbin

“…Cancer vaccines consisting of tumor-associated antigens (TAAs) can initiate a powerful antitumor immune response through antigen-presenting cells, such as…”
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Vanadyl nanocomplexes enhance photothermia-induced cancer immunotherapy to inhibit tumor metastasis and recurrence by Hu, Doudou, Xu, Hongxia, Zhang, Wei, Xu, Xiaodan, Xiao, Bing, Shi, Xueying, Zhou, Zhuxian, Slater, Nigel K.H., Shen, Youqing, Tang, Jianbin

“…Conventional photothermal therapy (PTT) is insufficient to induce a strong and potent anti-tumor immune response. Herein, we present a vanadyl nanocomplex,…”
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Model-based process development of continuous chromatography for antibody capture: A case study with twin-column system by Shi, Ce, Gao, Zong-Ye, Zhang, Qi-Lei, Yao, Shan-Jing, Slater, Nigel K.H., Lin, Dong-Qiang

“…•A mechanistic model was developed to predict breakthrough curves and continuous process performance.•Effects of key operating parameters on continuous capture…”
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In situ formed reactive oxygen species-responsive dipyridamole prodrug hydrogel: Spatiotemporal drug delivery for chemoimmunotherapy by Xiao, Bing, Shi, Xueying, Xu, Xiaodan, Liu, Jiwei, Pan, Yixuan, Xu, Hongxia, Sun, Wenjing, Slater, Nigel K.H., Patra, Hirak K., Gao, Jianqing, Shen, Youqing, Tang, Jianbin

“…In the realm of combined cancer immunotherapy, the strategic combination of therapeutics targeting both cancer cells and macrophages holds immense potential…”
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Model-based process development and evaluation of twin-column continuous capture processes with Protein A affinity resin by Sun, Yan-Na, Shi, Ce, Zhang, Qi-Lei, Yao, Shan-Jing, Slater, Nigel K.H., Lin, Dong-Qiang

“…•A model-based approach was used for continuous capture process development.•Twin-column continuous capture with MabSelect PrismA affinity resin was…”
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Combination of Cryo‐Shocked M1 Macrophages and Lonidamine Nanodrugs Enables Potent Chemo‐Immunotherapy by Shi, Xueying, Xiao, Bing, Xu, Xiaodan, Pan, Yixuan, Xiang, Jiajia, Shao, Shiqun, Zhou, Zhuxian, Huang, Feihe, Gao, Jianqing, Slater, Nigel K. H., Shen, Youqing, Tang, Jianbin

“…Abstract Therapeutics targeting immune checkpoints have achieved astonishing clinical success in cancer treatment. However, these therapies can hardly adapt to…”
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Enhancing the functionality of a microscale bioreactor system as an industrial process development tool for mammalian perfusion culture by Sewell, David J, Turner, Richard, Field, Ray, Holmes, William, Pradhan, Rahul, Spencer, Christopher, Oliver, Stephen G, Slater, Nigel KH, Dikicioglu, Duygu

“…Without a scale‐down model for perfusion, high resource demand makes cell line screening or process development challenging, therefore, potentially successful…”
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Comparison of Protein A affinity resins for twin-column continuous capture processes: Process performance and resin characteristics by Sun, Yan-Na, Shi, Ce, Zhang, Qi-Lei, Slater, Nigel K.H., Jungbauer, Alois, Yao, Shan-Jing, Lin, Dong-Qiang

“…•Four Protein A affinity resins were evaluated for twin-column continuous capture.•Suitable feedstock and operating conditions were determined for different…”
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Multifunctional Nanoassembly for MRI-Trackable Dendritic Cell Dependent and Independent Photoimmunotherapy by Xiao, Bing, Xu, Hongxia, Xu, Xiaodan, Pan, Yixuan, Shi, Xueying, Yuan, Pengcheng, Slater, Nigel K. H., Sun, Wenjing, Tang, Jianbin, Shen, Youqing, Gao, Jianqing

“…Immunotherapy has emerged as a triumph in the treatment of malignant cancers. Nevertheless, current immunotherapeutics are insufficient in addressing tumors…”
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Correction: Middle Eastern nurses' views/experiences of work and well-being with the support measures during past disease outbreaks and COVID-19: a qualitative systematic review by Marair, Sara Ahmed, Slater, Nigel

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Characterisation of zinc delivery from a nipple shield delivery system using a breastfeeding simulation apparatus by Scheuerle, Rebekah L, Bruggraber, Sylvaine F A, Gerrard, Stephen E, Kendall, Richard A, Tuleu, Catherine, Slater, Nigel K H

“…Zinc delivery from a nipple shield delivery system (NSDS), a novel platform for administering medicines to infants during breastfeeding, was characterised…”
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