Search Results - "Slater, N.K.H."

Bioprocess modelling of biohydrogen production by Rhodopseudomonas palustris: Model development and effects of operating conditions on hydrogen yield and glycerol conversion efficiency by Zhang, D., Xiao, N., Mahbubani, K.T., del Rio-Chanona, E.A., Slater, N.K.H., Vassiliadis, V.S.

“…This research explores the photofermentation of glycerol to hydrogen by Rhodopseudomonas palustris, with the objective to maximise hydrogen production. Two…”
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The development of a weak anion micro-capillary film for protein chromatography by Kouyoumdjian, A.J.M., Lazar, R.A., Slater, N.K.H.

“…•A weak micro-capillary film anion exchanger was developed.•Full characterisation of the membrane and the ion exchanger was conducted.•The exchanger was shown…”
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A microporous walled micro-capillary film module for cation-exchange protein chromatography by Mandal, I., Townsend, M.J., Darton, N.J., Bonyadi, S., Slater, N.K.H.

“…Opportunities exist in preparative chromatography for alternative chromatography media that possess high binding capacity and throughput, but are also…”
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Lentivirus capture directly from cell culture with Q-functionalised microcapillary film chromatography by Darton, N.J., Darling, D., Townsend, M.J., McNally, D.J., Farzaneh, F., Slater, N.K.H.

“…▸ New disposable adsorbent material developed for fast anion-exchange capture of nano-complexes. ▸ No sample prefiltering, clarification or pre-processing…”
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Fast cation-exchange separation of proteins in a plastic microcapillary disc by Darton, N.J., Reis, N.M., Mackley, M.R., Slater, N.K.H.

“…A novel disposable adsorbent material for fast cation-exchange separation of proteins was developed based on plastic microcapillary films (MCFs). A MCF…”
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Dual affinity method for plasmid DNA purification in aqueous two-phase systems by Barbosa, H.S.C., Hine, A.V., Brocchini, S., Slater, N.K.H., Marcos, J.C.

“…The DNA binding fusion protein, LacI–His 6–GFP, together with the conjugate PEG–IDA–Cu(II) (10 kDa) was evaluated as a dual affinity system for the pUC19…”
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Affinity partitioning of plasmid DNA with a zinc finger protein by Barbosa, H., Hine, A.V., Brocchini, S., Slater, N.K.H., Marcos, J.C.

“…The affinity isolation of pre-purified plasmid DNA (pDNA) from model buffer solutions using native and poly(ethylene glycol) (PEG) derivatized zinc finger–GST…”
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A facile route to a polymer-supported IBX reagent by Lei, Z., Denecker, C., Jegasothy, S., Sherrington, D.C., Slater, N.K.H., Sutherland, A.J.

“…A three-step preparation of a polymer-supported IBX reagent from poly( p-methylstyrene) is reported. This reagent has been used successfully for the efficient…”
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Effect of Freezing Rates and Excipients on the Infectivity of a Live Viral Vaccine during Lyophilization by Zhai, Suling, Hansen, Raino K., Taylor, Richard, Skepper, Jeremy N., Sanches, Raquel, Slater, Nigel K. H.

“…Lyophilization is the most popular method for achieving improved stability of labile biopharmaceuticals, but a significant fraction of product activity can be…”
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Membrane permeabilisation for the cryopreservation of mammalian cells by Mercado, S.A., Slater, N.K.H.

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Development of a disposable micro-capillary film grafted with peptide ligands for immunoadsorption by Li, Jiawen, Lin, Dongqiang, Yao, Shanjing, Slater, N.K.H., Zhang, Qilei

“…Traditional chromatographic techniques used in downstream processes of biomolecule manufacturing are often time-consuming and expensive. In this study, a…”
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Oral vaccines: A new formulation that protects live bacterial vaccines from intestinal bile using bile adsorbing resins by Edwards, A.D., Slater, N.K.H.

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The functional and structural effects of an amphipathic pH responsive biopolymer: A comprehensive study in osteosarcoma cells by Mercado, S.A., Slater, N.K.H.

“…[Display omitted] •Cytotoxicity of an amphipathic biopolymer, PP-50, was evaluated in osteosarcoma cells.•Cellular metabolic activity, membrane integrity and…”
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Facile F(ab′) 2 Manufacturing: Strategies for the Production of Snake Antivenoms by Kumpalume, P., Boushaba, R., Jones, R.G.A., Slater, N.K.H.

“…Asimple process for the manufacture of polyclonal F(ab′) 2 fragments that might be adopted for the facile preparation of antivenoms is described. The…”
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Optimised concentration and purification of retroviruses using membrane chromatography by McNally, D.J., Darling, D., Farzaneh, F., Levison, P.R., Slater, N.K.H.

“…•An in investigation in to the use of membrane chromatography for the purification of a γ-retrovirus was undertaken.•The first report of a capacity for…”
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Oxygen Transfer in Stirred Bioreactors Under Animal Cell Culture Conditions by Langheinrich, C., Nienow, A.W., Eddleston, T., Stevenson, N.C., Emery, A.N., Clayton, T.M., Slater, N.K.H.

“…Bioreactors designed for animal cell culture may differ significantly in reactor geometry and operating conditions from those used for microbial fermentations…”
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Fermenter balancing for semi-continuous, multi-tank mammalian cell culture processes by Dey, S., Marshall, C., Slater, N.K.H.

“…Process design and scheduling for optimal economic return from semi-continuous, multi-stage mammalian cell culture processes are considered. Heuristics are…”
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Increased cryosurvival of osteosarcoma cells using an amphipathic pH-responsive polymer for trehalose uptake by Mercado, S.A., Slater, N.K.H.

“…Amphipathic pH-responsive polymers have shown to increase the permeability of cell membranes to trehalose hence improving the cryopreservation of mammalian…”
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Mixing in Process Vessels Used in Biopharmaceutical Manufacturing by Ram, Kripa, Vickroy, T. Bruce, Lamb, Keith A., Slater, Nigel K. H., Dennis, John S., Duffy, Louise E.

“…The use of nonbaffled vessels for mixing applications is becoming common in the biopharmaceutical industry but is not sufficiently well studied. Orientation of…”
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Effect of bore fluid composition on microstructure and performance of a microporous hollow fibre membrane as a cation-exchange substrate by Lazar, R.A., Mandal, I., Slater, N.K.H.

“…•EVOH hollow fibre membranes were produced with different bore fluids.•Fibre surfaces were functionalised into cation-exchange adsorbers.•Membrane pore size…”
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