Search Results - "Slater, Josefine"

Concentrations of Co-Administered Meropenem and Vancomycin in Spinal Tissues Relevant for the Treatment of Pyogenic Spondylodiscitis-An Experimental Microdialysis Study by Slater, Josefine, Stilling, Maiken, Hanberg, Pelle, Vittrup, Sofus, Bruun Knudsen, Martin, Kousgaard Tøstesen, Sara, Olsen Kipp, Josephine, Bue, Mats

“…Co-administration of meropenem and vancomycin has been suggested as a systemic empirical antibiotic treatment of pyogenic spondylodiscitis. The aim of this…”
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Flucloxacillin bone and soft tissue concentrations assessed by microdialysis in pigs after intravenous and oral administration by Bendtsen, Mathias A F, Bue, Mats, Hanberg, Pelle, Slater, Josefine, Thomassen, Maja B, Hansen, Jakob, Søballe, Kjeld, Öbrink-Hansen, Kristina, Stilling, Maiken

“…Flucloxacillin is commonly administered intravenously for perioperative antimicrobial prophylaxis, while oral administration is typical for prophylaxis…”
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Moxifloxacin Concentrations in the Knee Joint, Tibial Bone, and Soft Tissue When Combined with Rifampicin: A Randomized Porcine Microdialysis Study by Slater, Josefine, Stilling, Maiken, Hanberg, Pelle, Fichtner Bendtsen, Mathias Alrø, Jørgensen, Andrea René, Søballe, Kjeld, Jørgensen, Nis Pedersen, Bue, Mats

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CD46 is a potent co-stimulatory receptor on CD8+ T cells by Hansen, Aida Solhoej, Slater, Josefine, Biltoft, Mette, Höllsberg, Per

“…Abstract Upon activation CD8+ T cells may proliferate extensively and become specialized effector cells with an important role in clearing viral infections…”
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Population Pharmacokinetics of Flucloxacillin In Bone and Soft Tissue– Standard Dosing is Not Sufficient to Achieve Therapeutic Concentrations by Öbrink-Hansen, Kristina, Pham, Anh Duc, Bue, Mats, Hanberg, Pelle, Bendtsen, Mathias, Slater, Josefine, Friberg, Lena E., Thorsted, Anders, Stilling, Maiken

“…Purpose Flucloxacillin is a β-lactam penicillin commonly used in the treatment of bone and soft tissue infections. In a recent porcine study, we found…”
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Rifampicin does not reduce moxifloxacin concentrations at the site of infection and may not improve treatment outcome of a one-stage exchange surgery protocol of implant-associated osteomyelitis lesions in a porcine model by Vittrup, Sofus, Jensen, Louise Kruse, Hartmann, Katrine Top, Aalbaek, Bent, Hanberg, Pelle, Slater, Josefine, Hvistendahl, Magnus Andreas, Stilling, Maiken, Jørgensen, Nis Pedersen, Bue, Mats

“…We aimed to evaluate moxifloxacin steady-state concentrations in infected bone and soft tissue and to explore the additive microbiological and pathological…”
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Steady-state concentrations of flucloxacillin in porcine vertebral cancellous bone and intervertebral disc following oral and intravenous administration assessed by microdialysis by Bendtsen, Mathias A. F., Hanberg, Pelle, Slater, Josefine, Hansen, Jakob, Öbrink-Hansen, Kristina, Stilling, Maiken, Bue, Mats

“…Aims Flucloxacillin is a frequently used antibiotic in the treatment of spondylodiscitis. We assessed steady-state concentrations and time above minimal…”
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Moxifloxacin Concentrations in the Knee Joint, Tibial Bone, and Soft Tissue When Combined with Rifampicin: A Randomized Porcine Microdialysis Study by Slater, Josefine, Stilling, Maiken, Hanberg, Pelle, Fichtner Bendtsen, Mathias Alrø, Jørgensen, Andrea René, Søballe, Kjeld, Jørgensen, Nis Pedersen, Bue, Mats

“…Peri and postoperative antibiotics are key adjuvant treatment tools in the management of periprosthetic joint infection (PJI). The aim of this study was to…”
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Effects of rifampicin on moxifloxacin concentrations in porcine cervical spine: a randomized microdialysis study by Slater, Josefine, Hanberg, Pelle, Bendtsen, Mathias Alrø Fichtner, Jørgensen, Andrea René, Greibe, Eva, Søballe, Kjeld, Bue, Mats, Pedersen Jørgensen, Nis, Stilling, Maiken

“…Pyogenic spondylodiscitis remains a therapeutic challenge, as demonstrated by divergent treatment guidelines. The combination of moxifloxacin and rifampicin…”
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Oncological results and morbidity following intended curative resection and free jejunal graft reconstruction of cervical esophageal cancer: a retrospective Danish consecutive cohort study by Erichsen, Sune Brinck, Slater, Josefine, Kiil, Birgitte Jul, Petersen, Torben Ingemann, Katballe, Niels, Nielsen, Mette Bak, Pikelis, Arunas, Nordsmark, Marianne, Kjaer, Daniel

“…Summary Background The role of surgery in treatment of locally advanced cervical esophageal cancer (CEC) remains debated. In the European and American…”
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CD46 is a potent co-stimulatory receptor for expansion of human IFN-γ-producing CD8+ T cells by Hansen, Aida S., Slater, Josefine, Biltoft, Mette, Bundgaard, Bettina B., Møller, Bjarne K., Höllsberg, Per

“…•Activation of CD46 induces rapid down-modulation of CD46 expression on the surface of CD8+ T cells.•CD46 co-stimulation potently induces CD8+ T cell…”
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Vancomycin bone and tissue concentrations following tibial intraosseous administration – evaluated in a porcine model by Olsen Kipp, Josephine, Hanberg, Pelle, Slater, Josefine, Møller Nielsen, Line, Storgaard Jakobsen, Stig, Stilling, Maiken, Bue, Mats

“…Introduction. Systemic perioperative vancomycin may not provide sufficient prophylactic target-site concentrations in the prevention of prosthetic joint…”
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