Search Results - "Slagle, Paul"

Exchanging Interleukin-8 and Melanoma Growth-stimulating Activity Receptor Binding Specificities by Lowman, Henry B., Slagle, Paul H., DeForge, Laura E., Wirth, Cynthia M., Gillece-Castro, Beth L., Bourell, James H., Fairbrother, Wayne J.

“…Interleukin-8 (IL-8), a C X C chemokine, is known to bring about chemotaxis and activation of neutrophils through high affinity binding to at least two…”
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AZ17: a new bispecific drug targeting IL-6 and IL-23 with potential clinical use—improves psoriasis in a human xenograft transplantation model by Stenderup, Karin, Rosada, Cecilia, Shanebeck, Kurt, Brady, William, Van Brunt, Michael P., King, Gordon, Marelli, Marcello, Slagle, Paul, Xu, Hengyu, Nairn, Natalie W., Johnson, Jeffrey, Wang, Aijun A., Li, Gary, Thornton, Kenneth C., Dam, Tomas N., Grabstein, Kenneth H.

“…Targeting more than one molecule in multifactorial diseases involving several disease mediators may provide improved therapeutic efficacy. Psoriasis is a…”
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P-080: Medication factors impacting enrollment in Alzheimer’s disease trials: Insight from objective healthcare data by Riordan, Henry, Moore, Christine, Schaeffer, James, Slagle, Paul

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P-080 by Riordan, Henry, Moore, Christine, Schaeffer, James, Slagle, Paul

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Antitumor vaccination with HER‐2‐derived recombinant antigens by Vidovic, Damir, Graddis, Thomas, Chen, Feng, Slagle, Paul, Diegel, Michael, Stepan, Lara, Laus, Reiner

“…Certain types of malignant tumors overexpress HER‐2, a transmembrane glycoprotein of the class I receptor tyrosine kinase erbB family. To develop an effective…”
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Monomeric variants of IL‐8: Effects of side chain substitutions and solution conditions upon dimer formation by Lowman, Henry B., Fairbrother, Wayne J., Slagle, Paul H., Kabakoff, Rhona, Hebert, Caroline A., Liu, Jun, Shire, Steven

“…IL‐8 dimers have been observed in NMR and X‐ray structures of the protein. We have engineered IL‐8 monomers by mutations of residues throughout the dimer…”
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Monomeric variants of IL-8: Effects of side chain substitutions and solution conditions upon dimer formation: Monomeric forms of IL-8 by Lowman, Henry B., Fairbrother, Wayne J., Slagle, Paul H., Kabakoff, Rhona, Hebert, Caroline A., Liu, Jun, Shire, Steven

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