Search Results - "Skyler, Jay"

Novel therapies with precision mechanisms for type 2 diabetes mellitus by Perreault, Leigh, Skyler, Jay S., Rosenstock, Julio

“…Type 2 diabetes mellitus (T2DM) is one of the greatest health crises of our time and its prevalence is projected to increase by >50% globally by 2045…”
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Hope vs hype: where are we in type 1 diabetes? by Skyler, Jay S.

“…Much progress has been made in type 1 diabetes research. Biological replacement of islet function has been achieved with pancreas transplantation and with…”
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The Management of Type 1 Diabetes in Adults. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) by Holt, Richard I G, DeVries, J Hans, Hess-Fischl, Amy, Hirsch, Irl B, Kirkman, M Sue, Klupa, Tomasz, Ludwig, Barbara, Nørgaard, Kirsten, Pettus, Jeremy, Renard, Eric, Skyler, Jay S, Snoek, Frank J, Weinstock, Ruth S, Peters, Anne L

“…The American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) convened a writing group to develop a consensus statement…”
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The management of type 1 diabetes in adults. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) by Holt, Richard I. G., DeVries, J. Hans, Hess-Fischl, Amy, Hirsch, Irl B., Kirkman, M. Sue, Klupa, Tomasz, Ludwig, Barbara, Nørgaard, Kirsten, Pettus, Jeremy, Renard, Eric, Skyler, Jay S., Snoek, Frank J., Weinstock, Ruth S., Peters, Anne L.

“…The American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) convened a writing group to develop a consensus statement…”
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Weekly Insulin Becoming a Reality by Skyler, Jay S.

“…Buoyed by the successful use of once-weekly glucagon-like peptide 1 receptor agonists (GLP-1 RA) for the treatment of type 2 diabetes, manufacturers have begun…”
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Prevention and reversal of type 1 diabetes--past challenges and future opportunities by Skyler, Jay S

“…Over the past three decades there have been a number of clinical trials directed at interdicting the type 1 diabetes (T1D) disease process in an attempt to…”
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Practical recommendations for the management of diabetes in patients with COVID-19 by Bornstein, Stefan R, Rubino, Francesco, Khunti, Kamlesh, Mingrone, Geltrude, Hopkins, David, Birkenfeld, Andreas L, Boehm, Bernhard, Amiel, Stephanie, Holt, Richard IG, Skyler, Jay S, DeVries, J Hans, Renard, Eric, Eckel, Robert H, Zimmet, Paul, Alberti, Kurt George, Vidal, Josep, Geloneze, Bruno, Chan, Juliana C, Ji, Linong, Ludwig, Barbara

“…Diabetes is one of the most important comorbidities linked to the severity of all three known human pathogenic coronavirus infections, including severe acute…”
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Empagliflozin as Adjunctive to Insulin Therapy in Type 1 Diabetes: The EASE Trials by Rosenstock, Julio, Marquard, Jan, Laffel, Lori M, Neubacher, Dietmar, Kaspers, Stefan, Cherney, David Z, Zinman, Bernard, Skyler, Jay S, George, Jyothis, Soleymanlou, Nima, Perkins, Bruce A

“…To evaluate the safety and efficacy of empagliflozin 10- and 25-mg doses plus a unique lower dose (2.5 mg) as adjunct to intensified insulin in patients with…”
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Importance of residual insulin secretion in type 1 diabetes by Skyler, Jay S

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The artificial pancreas: current status and future prospects in the management of diabetes by Peyser, Thomas, Dassau, Eyal, Breton, Marc, Skyler, Jay S.

“…Recent advances in insulins, insulin pumps, continuous glucose‐monitoring systems, and control algorithms have resulted in an acceleration of progress in the…”
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Differentiation of Diabetes by Pathophysiology, Natural History, and Prognosis by Skyler, Jay S, Bakris, George L, Bonifacio, Ezio, Darsow, Tamara, Eckel, Robert H, Groop, Leif, Groop, Per-Henrik, Handelsman, Yehuda, Insel, Richard A, Mathieu, Chantal, McElvaine, Allison T, Palmer, Jerry P, Pugliese, Alberto, Schatz, Desmond A, Sosenko, Jay M, Wilding, John P H, Ratner, Robert E

“…The American Diabetes Association, JDRF, the European Association for the Study of Diabetes, and the American Association of Clinical Endocrinologists convened…”
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Staging presymptomatic type 1 diabetes: a scientific statement of JDRF, the Endocrine Society, and the American Diabetes Association by Insel, Richard A, Dunne, Jessica L, Atkinson, Mark A, Chiang, Jane L, Dabelea, Dana, Gottlieb, Peter A, Greenbaum, Carla J, Herold, Kevan C, Krischer, Jeffrey P, Lernmark, Åke, Ratner, Robert E, Rewers, Marian J, Schatz, Desmond A, Skyler, Jay S, Sosenko, Jay M, Ziegler, Anette-G

“…Insights from prospective, longitudinal studies of individuals at risk for developing type 1 diabetes have demonstrated that the disease is a continuum that…”
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An Anti-CD3 Antibody, Teplizumab, in Relatives at Risk for Type 1 Diabetes by Herold, Kevan C, Bundy, Brian N, Long, S. Alice, Bluestone, Jeffrey A, DiMeglio, Linda A, Dufort, Matthew J, Gitelman, Stephen E, Gottlieb, Peter A, Krischer, Jeffrey P, Linsley, Peter S, Marks, Jennifer B, Moore, Wayne, Moran, Antoinette, Rodriguez, Henry, Russell, William E, Schatz, Desmond, Skyler, Jay S, Tsalikian, Eva, Wherrett, Diane K, Ziegler, Anette-Gabriele, Greenbaum, Carla J

“…In this trial, high-risk nondiabetic relatives of patients with type 1 diabetes were randomly assigned to receive teplizumab (an anti-CD3 monoclonal antibody)…”
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Cardiovascular Outcomes Trials in Type 2 Diabetes: Where Do We Go From Here? Reflections From a Diabetes Care Editors' Expert Forum by Cefalu, William T, Kaul, Sanjay, Gerstein, Hertzel C, Holman, Rury R, Zinman, Bernard, Skyler, Jay S, Green, Jennifer B, Buse, John B, Inzucchi, Silvio E, Leiter, Lawrence A, Raz, Itamar, Rosenstock, Julio, Riddle, Matthew C

“…In December 2008, the U.S. Food and Drug Administration issued guidance to the pharmaceutical industry setting new expectations for the development of…”
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New insights into halting type 1 diabetes by Skyler, Jay S

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The effect of age on longitudinal measures of beta cell function and insulin sensitivity during the progression of early stage type 1 diabetes by Ferrannini, Ele, Mari, Andrea, Monaco, Gabriela S. F., Skyler, Jay S., Evans-Molina, Carmella

“…Aim/hypothesis The risk of progressing from autoantibody positivity to type 1 diabetes is inversely related to age. Separately, whether age influences patterns…”
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Allogeneic Mesenchymal Precursor Cells in Type 2 Diabetes: A Randomized, Placebo-Controlled, Dose-Escalation Safety and Tolerability Pilot Study by Skyler, Jay S, Fonseca, Vivian A, Segal, Karen R, Rosenstock, Julio

“…To assess the safety, tolerability, and feasibility of adult allogeneic bone marrow-derived mesenchymal precursor cells (MPCs) in type 2 diabetes inadequately…”
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Stopping Type 1 Diabetes: Attempts to Prevent or Cure Type 1 Diabetes in Man by SKYLER, Jay S, RICORDI, Camillo

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International Consensus on Risk Management of Diabetic Ketoacidosis in Patients With Type 1 Diabetes Treated With Sodium-Glucose Cotransporter (SGLT) Inhibitors by Danne, Thomas, Garg, Satish, Peters, Anne L, Buse, John B, Mathieu, Chantal, Pettus, Jeremy H, Alexander, Charles M, Battelino, Tadej, Ampudia-Blasco, F Javier, Bode, Bruce W, Cariou, Bertrand, Close, Kelly L, Dandona, Paresh, Dutta, Sanjoy, Ferrannini, Ele, Fourlanos, Spiros, Grunberger, George, Heller, Simon R, Henry, Robert R, Kurian, Martin J, Kushner, Jake A, Oron, Tal, Parkin, Christopher G, Pieber, Thomas R, Rodbard, Helena W, Schatz, Desmond, Skyler, Jay S, Tamborlane, William V, Yokote, Koutaro, Phillip, Moshe

“…Sodium-glucose cotransporter (SGLT) inhibitors are new oral antidiabetes medications shown to effectively reduce glycated hemoglobin (A1C) and glycemic…”
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Co-stimulation modulation with abatacept in patients with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled trial by Orban, Tihamer, MD, Bundy, Brian, PhD, Becker, Dorothy J, Prof, DiMeglio, Linda A, MD, Gitelman, Stephen E, Prof, Goland, Robin, Prof, Gottlieb, Peter A, Prof, Greenbaum, Carla J, MD, Marks, Jennifer B, Prof, Monzavi, Roshanak, MD, Moran, Antoinette, Prof, Raskin, Philip, Prof, Rodriguez, Henry, Prof, Russell, William E, Prof, Schatz, Desmond, Prof, Wherrett, Diane, MD, Wilson, Darrell M, Prof, Krischer, Jeffrey P, Prof, Skyler, Jay S, Dr, Prof

“…Summary Background The immunopathogenesis of type 1 diabetes mellitus is associated with T-cell autoimmunity. To be fully active, immune T cells need a…”
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